STRINGSTRING
NFRKB NFRKB POLE3 POLE3 NAIP NAIP RCBTB1 RCBTB1 XPA XPA SPATS2 SPATS2 AV530_017028 AV530_017028 ERCC5 ERCC5 CHD1L CHD1L CUL4A CUL4A POLE POLE HMGN1 HMGN1 AV530_004421 AV530_004421 RAD23B RAD23B RPS27A RPS27A CDK7 CDK7 AV530_008697 AV530_008697 AV530_017641 AV530_017641 INO80D INO80D POLK POLK USP40 USP40 POLE2 POLE2 AV530_007135 AV530_007135 AV530_017627 AV530_017627 AV530_000249 AV530_000249 GTF2H4 GTF2H4 AV530_003887 AV530_003887 AV530_003886 AV530_003886 KCTD2 KCTD2 ATAD5 ATAD5 SUMO2 SUMO2 AV530_016344 AV530_016344 USP7 USP7 UBE2I UBE2I MEIOB MEIOB COPS3 COPS3 AV530_009546 AV530_009546 ERCC8 ERCC8 PCNA PCNA KXD1 KXD1 POLR2E POLR2E AV530_018941 AV530_018941 POLD3 POLD3 AV530_007031 AV530_007031 UBE2N UBE2N RFC5 RFC5 COPS7B COPS7B ACTR5 ACTR5 ERCC6 ERCC6 TCEA2 TCEA2 POLD2 POLD2 POLR2K POLR2K PPP1R42 PPP1R42 COPS5 COPS5 TCEA1 TCEA1 UBE2V2 UBE2V2 AV530_013625 AV530_013625 AV530_013971 AV530_013971 AQR AQR DDB2 DDB2 INO80 INO80 YY1-2 YY1-2 RPA3 RPA3 NRDE2 NRDE2 YY1 YY1 MNAT1 MNAT1 RFC3 RFC3 AV530_014737 AV530_014737 ACTR8 ACTR8 PARP3 PARP3 COPS8 COPS8 ERCC3 ERCC3 POLR2D POLR2D RFC4 RFC4 GPS1 GPS1 ERCC4 ERCC4 VWA5B2 VWA5B2 POLR2H POLR2H ISY1 ISY1 POLR2J POLR2J RFC2 RFC2 LIG3 LIG3 RPA1 RPA1 UBC UBC COQ9 COQ9 AV530_004707 AV530_004707 AV530_009474 AV530_009474 TCEANC2 TCEANC2 SUMO1 SUMO1 ERCC2 ERCC2 COPS4 COPS4 CETN3 CETN3 CCNH CCNH POLR2B POLR2B AV530_010142 AV530_010142 GTF2H3 GTF2H3 DDB1 DDB1 AV530_013466 AV530_013466 PRPF19 PRPF19 GTF2H1 GTF2H1 POLR2L POLR2L PHF3 PHF3 AV530_005781 AV530_005781 USP45 USP45 GTF2H5 GTF2H5 RPA2 RPA2 PARP1 PARP1 RUVBL1 RUVBL1 XPC XPC PPIE PPIE RFC1 RFC1 COPS2 COPS2 UVSSA UVSSA AV530_017169 AV530_017169 PIAS1 PIAS1 RNF111 RNF111 TCEANC TCEANC TCEA3 TCEA3 VTCN1 VTCN1 COPS7A COPS7A RBX1 RBX1 RPAP3 RPAP3 EP300 EP300 POLR2F POLR2F INO80C INO80C ZNF830 ZNF830
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFRKBNuclear factor related to kappa-B-binding protein isoform A. (1408 aa)
POLE3DNA polymerase epsilon subunit 3. (171 aa)
NAIPBaculoviral IAP repeat-containing protein 1. (1198 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (531 aa)
XPADNA repair protein complementing XP-A cells. (180 aa)
SPATS2Spermatogenesis-associated serine-rich protein 2. (799 aa)
AV530_017028RCC1 and BTB domain-containing protein 2. (591 aa)
ERCC5DNA repair protein complementing XP-G cells. (1128 aa)
CHD1LChromodomain-helicase-DNA-binding protein 1-like. (887 aa)
CUL4ACullin-4A; Belongs to the cullin family. (770 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2276 aa)
HMGN1Non-histone chromosomal protein HMG-14. (102 aa)
AV530_004421Uncharacterized protein. (606 aa)
RAD23BUV excision repair RAD23-like protein B. (400 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
CDK7Cyclin-dependent kinase 7. (226 aa)
AV530_008697Protein kinase domain-containing protein. (86 aa)
AV530_017641HELICc2 domain-containing protein. (68 aa)
INO80DINO80 complex subunit D. (1030 aa)
POLKDNA polymerase kappa isoform B. (944 aa)
USP40Ubiquitin carboxyl-terminal hydrolase 40; Belongs to the peptidase C19 family. (1289 aa)
POLE2DNA polymerase epsilon subunit 2. (315 aa)
AV530_007135DNA_pol_E_B domain-containing protein. (226 aa)
AV530_017627UBA domain-containing protein. (117 aa)
AV530_000249Short transient receptor potential channel 2-like. (325 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (320 aa)
AV530_003887CULLIN_2 domain-containing protein; Belongs to the cullin family. (614 aa)
AV530_003886Cullin domain-containing protein; Belongs to the cullin family. (200 aa)
KCTD2BTB/POZ domain-containing protein KCTD2 isoform A. (309 aa)
ATAD5ATPase family AAA domain-containing protein 5. (1801 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
AV530_016344Von Willebrand factor A domain-containing protein 5A-like. (757 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1103 aa)
UBE2ISUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform B. (493 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
AV530_009546PAPA-1 domain-containing protein. (380 aa)
ERCC8DNA excision repair protein ERCC-8 isoform B. (434 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
KXD1KxDL motif-containing protein 1. (190 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
AV530_018941Uncharacterized protein. (216 aa)
POLD3DNA polymerase delta subunit 3 isoform B. (405 aa)
AV530_007031Uncharacterized protein. (93 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
RFC5Replication factor C subunit 5. (255 aa)
COPS7BCOP9 signalosome complex subunit 7b. (259 aa)
ACTR5Actin-related protein 5; Belongs to the actin family. (607 aa)
ERCC6DNA excision repair protein ERCC-6. (1554 aa)
TCEA2Transcription elongation factor A protein 2. (325 aa)
POLD2DNA polymerase delta subunit 2. (407 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (128 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (334 aa)
COPS5COP9 signalosome complex subunit 5 isoform B. (342 aa)
TCEA1Transcription elongation factor A protein 1 isoform B. (304 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (144 aa)
AV530_013625MitMem_reg domain-containing protein. (103 aa)
AV530_013971RNA_pol_Rpb1_7 domain-containing protein. (101 aa)
AQRIntron-binding protein aquarius. (1467 aa)
DDB2DNA damage-binding protein 2 isoform B. (516 aa)
INO80DNA helicase INO80. (1471 aa)
YY1-2Transcriptional repressor protein YY1. (226 aa)
RPA3Replication protein A subunit. (121 aa)
NRDE2NRDE2-like protein. (1170 aa)
YY1Transcriptional repressor protein YY1. (269 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
RFC3Replication factor C subunit 3. (356 aa)
AV530_014737HELICc2 domain-containing protein. (147 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
PARP3Poly [ADP-ribose] polymerase. (180 aa)
COPS8COP9 signalosome complex subunit 8. (207 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (780 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
RFC4Replication factor C subunit 4. (362 aa)
GPS1COP9 signalosome complex subunit 1. (471 aa)
ERCC4DNA repair endonuclease XPF. (961 aa)
VWA5B2Von Willebrand factor A domain-containing protein 5B2. (1106 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ISY1Pre-mRNA-splicing factor ISY1-like protein. (310 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
RFC2Replication factor C subunit 2. (355 aa)
LIG3DNA ligase. (904 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (646 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
COQ9Ubiquinone biosynthesis protein COQ9, mitochondrial. (634 aa)
AV530_004707CBFD_NFYB_HMF domain-containing protein. (70 aa)
AV530_009474Uncharacterized protein. (74 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (177 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (198 aa)
COPS4COP9 signalosome complex subunit 4. (406 aa)
CETN3Centrin-3. (167 aa)
CCNHCyclin-H; Belongs to the cyclin family. (321 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
AV530_010142Small ubiquitin-related modifier. (102 aa)
GTF2H3General transcription factor IIH subunit 3. (307 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
AV530_013466Uncharacterized protein. (130 aa)
PRPF19Pre-mRNA-processing factor 19. (504 aa)
GTF2H1General transcription factor IIH subunit 1. (581 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
PHF3PHD finger protein 3. (954 aa)
AV530_005781Uncharacterized protein. (1136 aa)
USP45Ubiquitin carboxyl-terminal hydrolase. (818 aa)
GTF2H5General transcription factor IIH subunit 5. (103 aa)
RPA2Replication protein A subunit. (271 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
XPCDNA repair protein complementing XP-C cells. (959 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
RFC1Replication factor C subunit 1. (1150 aa)
COPS2COP9 signalosome complex subunit 2 isoform B. (450 aa)
UVSSAUV-stimulated scaffold protein A isoform A. (429 aa)
AV530_017169Uncharacterized protein. (338 aa)
PIAS1E3 SUMO-protein ligase PIAS1. (651 aa)
RNF111E3 ubiquitin-protein ligase Arkadia isoform A. (1051 aa)
TCEANCTranscription elongation factor A N-terminal and central domain-containing protein. (360 aa)
TCEA3Transcription elongation factor A protein 3. (413 aa)
VTCN1V-set domain-containing T-cell activation inhibitor 1. (79 aa)
COPS7ACOP9 signalosome complex subunit 7a. (266 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
RPAP3RNA polymerase II-associated protein 3. (718 aa)
EP300Histone acetyltransferase p300. (1778 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
INO80CINO80 complex subunit C. (185 aa)
ZNF830Zinc finger protein 830. (362 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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