STRINGSTRING
VAV1 VAV1 AV530_019256 AV530_019256 SQSTM1 SQSTM1 UBE2D2 UBE2D2 CASP2 CASP2 AV530_012453 AV530_012453 CLIP4 CLIP4 TBK1 TBK1 BIRC2 BIRC2 USP2 USP2 AV530_002751 AV530_002751 AV530_002749 AV530_002749 AV530_002750 AV530_002750 WDR31 WDR31 VAV2 VAV2 TRAF1 TRAF1 ARHGDIA ARHGDIA AV530_018979 AV530_018979 AV530_000265 AV530_000265 AV530_011069 AV530_011069 ARHGEF7 ARHGEF7 MCF2L MCF2L ITSN1 ITSN1 TIAM1 TIAM1 RPS27A RPS27A SOS1 SOS1 ARHGEF33 ARHGEF33 ARHGEF37 ARHGEF37 NGF NGF MAPKAPK2 MAPKAPK2 TRIO TRIO AV530_004017 AV530_004017 ITGB3BP ITGB3BP FASLG FASLG VAV3 VAV3 GSAP GSAP OPTN OPTN SMPD3 SMPD3 AV530_015121 AV530_015121 AATF AATF CYLD CYLD ULK2 ULK2 ABR ABR UBC UBC MCF2L2 MCF2L2 PRKCI PRKCI NCSTN NCSTN AV530_007127 AV530_007127 NGEF NGEF AV530_005130 AV530_005130 AV530_008839 AV530_008839 AV530_008840 AV530_008840 TNFSF10 TNFSF10 ARHGEF12 ARHGEF12 AV530_004092 AV530_004092 AV530_007128 AV530_007128 AV530_003914 AV530_003914 XIAP XIAP KALRN KALRN TMEM198 TMEM198 OBSL1 OBSL1 UBE2D1-2 UBE2D1-2 AV530_002466 AV530_002466 AV530_002465 AV530_002465 SESTD1 SESTD1 AV530_008320 AV530_008320 AV530_009431 AV530_009431 FGD4 FGD4 AV530_017096 AV530_017096 USP4 USP4 PRDM4 PRDM4 ARHGEF5 ARHGEF5 OTUD1 OTUD1 TAX1BP1 TAX1BP1 AV530_008514 AV530_008514 AV530_000206 AV530_000206 AV530_000205 AV530_000205 PSEN1 PSEN1 TRAF6 TRAF6 NSMAF NSMAF IKBKB IKBKB BAG4 BAG4 UBE2L3 UBE2L3 ULK1 ULK1 AV530_019865 AV530_019865 ARHGEF39 ARHGEF39 NFKB1 NFKB1 UBE2D3 UBE2D3 ARHGEF38 ARHGEF38 AV530_018227 AV530_018227 AV530_004016 AV530_004016 CFLAR CFLAR CASP10 CASP10 FGD3 FGD3 AV530_009265 AV530_009265 NET1 NET1 FAM105A FAM105A TNFRSF10B TNFRSF10B AV530_007060 AV530_007060 SPPL2A SPPL2A AV530_007059 AV530_007059 BIRC7 BIRC7 AV530_007062 AV530_007062 FAS FAS ARHGEF6 ARHGEF6 MCF2 MCF2 AV530_010167 AV530_010167 SMPD2 SMPD2 AV530_019127 AV530_019127 SPATA2 SPATA2 MYD88 MYD88 ARHGEF26 ARHGEF26 AV530_009235 AV530_009235 APH1A APH1A AV530_009221 AV530_009221 AV530_018100 AV530_018100 AV530_018210 AV530_018210 PLEKHG5 PLEKHG5 TNFRSF25 TNFRSF25 ARHGEF10L ARHGEF10L TRAF2 TRAF2 AV530_008733 AV530_008733 AV530_016422 AV530_016422 KXD1 KXD1 AV530_008875 AV530_008875 AV530_014219 AV530_014219 STUB1 STUB1 NGFR NGFR AV530_013256 AV530_013256 FADD FADD ADAM17 ADAM17 ARHGEF10 ARHGEF10 TNFAIP3 TNFAIP3 TIAM2 TIAM2 AV530_011470 AV530_011470 PSEN2 PSEN2 ARHGEF3 ARHGEF3 AV530_017808 AV530_017808 AV530_009507 AV530_009507 ARHGEF17 ARHGEF17 AV530_011480 AV530_011480 CASP3 CASP3 AKAP13 AKAP13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VAV1Proto-oncogene vav. (365 aa)
AV530_019256Uncharacterized protein. (141 aa)
SQSTM1Sequestosome-1. (453 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (291 aa)
CASP2Caspase-2; Belongs to the peptidase C14A family. (568 aa)
AV530_012453Tumor necrosis factor receptor superfamily member 1A. (428 aa)
CLIP4CAP-Gly domain-containing linker protein 4. (132 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
BIRC2Baculoviral IAP repeat-containing protein 2 isoform A. (608 aa)
USP2Ubiquitin carboxyl-terminal hydrolase. (589 aa)
AV530_002751PA domain-containing protein. (264 aa)
AV530_002749Uncharacterized protein. (135 aa)
AV530_002750Uncharacterized protein. (213 aa)
WDR31WD repeat-containing protein 31. (340 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform B. (1478 aa)
TRAF1TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
ARHGDIARho GDP-dissociation inhibitor 1. (204 aa)
AV530_018979DH domain-containing protein. (196 aa)
AV530_000265Uncharacterized protein. (319 aa)
AV530_011069DUF4203 domain-containing protein. (258 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (803 aa)
MCF2LGuanine nucleotide exchange factor DBS isoform D. (1312 aa)
ITSN1Intersectin-1 isoform B. (1580 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1 isoform B. (1613 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
SOS1Son of sevenless-like protein 1. (1345 aa)
ARHGEF33Rho guanine nucleotide exchange factor 33. (643 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37 isoform B. (720 aa)
NGFBeta-nerve growth factor isoform A; Belongs to the NGF-beta family. (235 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa)
TRIOTriple functional domain protein isoform A. (3076 aa)
AV530_004017Caspase-8; Belongs to the peptidase C14A family. (490 aa)
ITGB3BPCentromere protein R. (198 aa)
FASLGTumor necrosis factor ligand superfamily member 6 isoform A; Belongs to the tumor necrosis factor family. (269 aa)
VAV3Guanine nucleotide exchange factor VAV3. (781 aa)
GSAPGamma-secretase-activating protein. (846 aa)
OPTNOptineurin isoform B. (603 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (662 aa)
AV530_015121Receptor-interacting serine/threonine-protein kinase 2. (590 aa)
AATFProtein AATF. (571 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD isoform B; Belongs to the peptidase C19 family. (954 aa)
ULK2Serine/threonine-protein kinase ULK2. (1077 aa)
ABRActive breakpoint cluster region-related protein isoform B. (901 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
MCF2L2Putative guanine nucleotide exchange factor MCF2L2 isoform A. (1255 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
NCSTNNicastrin. (703 aa)
AV530_007127DH domain-containing protein. (370 aa)
NGEFEphexin-1 isoform A. (684 aa)
AV530_005130Uncharacterized protein. (1782 aa)
AV530_008839WD_REPEATS_REGION domain-containing protein. (134 aa)
AV530_008840Guanine nucleotide-binding protein subunit beta-2-like 1. (268 aa)
TNFSF10Tumor necrosis factor ligand superfamily member 10 isoform B; Belongs to the tumor necrosis factor family. (295 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (285 aa)
AV530_004092RGS-like domain-containing protein. (127 aa)
AV530_007128Ras-GEF domain-containing protein. (352 aa)
AV530_003914Uncharacterized protein. (1481 aa)
XIAPE3 ubiquitin-protein ligase XIAP isoform A. (574 aa)
KALRNKalirin isoform D. (2951 aa)
TMEM198Transmembrane protein 198. (364 aa)
OBSL1Obscurin-like protein 1. (2197 aa)
UBE2D1-2Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
AV530_002466SAM domain-containing protein. (436 aa)
AV530_002465Mitogen-activated protein kinase kinase kinase MLT. (450 aa)
SESTD1SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
AV530_008320Uncharacterized protein. (198 aa)
AV530_009431Uncharacterized protein. (92 aa)
FGD4FYVE, RhoGEF and PH domain-containing protein 4. (829 aa)
AV530_017096ANK_REP_REGION domain-containing protein. (115 aa)
USP4Ubiquitin carboxyl-terminal hydrolase. (942 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (800 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1758 aa)
OTUD1OTU domain-containing protein 1. (350 aa)
TAX1BP1Tax1-binding protein 1 isoform A. (780 aa)
AV530_008514PH domain-containing protein. (132 aa)
AV530_000206Rho guanine nucleotide exchange factor 11. (912 aa)
AV530_000205RGS-like domain-containing protein. (173 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
NSMAFProtein FAN isoform B. (918 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (757 aa)
BAG4BAG family molecular chaperone regulator 4. (321 aa)
UBE2L3Ubiquitin-conjugating enzyme E2 L3 isoform A; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
ULK1Serine/threonine-protein kinase ULK1 isoform B. (1049 aa)
AV530_019865Gamma-secretase subunit Aph-1b. (256 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (338 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform B. (1044 aa)
UBE2D3Ubiquitin-conjugating enzyme E2 D3 isoform B; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
ARHGEF38Rho guanine nucleotide exchange factor 38. (347 aa)
AV530_018227RGS-like domain-containing protein. (314 aa)
AV530_004016Caspase-8; Belongs to the peptidase C14A family. (373 aa)
CFLARCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (443 aa)
CASP10Caspase-10; Belongs to the peptidase C14A family. (467 aa)
FGD3FYVE, RhoGEF and PH domain-containing protein 3. (867 aa)
AV530_009265Uncharacterized protein. (71 aa)
NET1Neuroepithelial cell-transforming 1 protein. (537 aa)
FAM105AInactive ubiquitin thioesterase FAM105A. (370 aa)
TNFRSF10BTumor necrosis factor receptor superfamily member 10A. (390 aa)
AV530_007060Calponin-homology (CH) domain-containing protein. (367 aa)
SPPL2ASignal peptide peptidase-like 2A isoform B. (534 aa)
AV530_007059DH domain-containing protein. (158 aa)
BIRC7Baculoviral IAP repeat-containing protein 7. (311 aa)
AV530_007062Uncharacterized protein. (97 aa)
FASTumor necrosis factor receptor superfamily member 6. (368 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6. (766 aa)
MCF2Proto-oncogene DBL. (1103 aa)
AV530_010167RGS-like domain-containing protein. (90 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (410 aa)
AV530_019127DH domain-containing protein. (365 aa)
SPATA2Spermatogenesis-associated protein 2. (523 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (276 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26 isoform A. (916 aa)
AV530_009235Uncharacterized protein. (665 aa)
APH1AGamma-secretase subunit APH-1A. (248 aa)
AV530_009221OTU domain-containing protein. (134 aa)
AV530_018100Protein-glutamine gamma-glutamyltransferase 6. (696 aa)
AV530_018210Protein-glutamine gamma-glutamyltransferase E. (692 aa)
PLEKHG5Pleckstrin-like proteiny domain-containing family G member 5 isoform B. (1076 aa)
TNFRSF25Tumor necrosis factor receptor superfamily member 25. (427 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10-like protein isoform A. (1278 aa)
TRAF2TNF receptor-associated factor. (472 aa)
AV530_008733RanBP-type and C3HC4-type zinc finger-containing protein 1-like. (363 aa)
AV530_016422IBR domain-containing protein. (170 aa)
KXD1KxDL motif-containing protein 1. (190 aa)
AV530_008875Ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (749 aa)
AV530_014219Uncharacterized protein. (179 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (313 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (392 aa)
AV530_013256Uncharacterized protein. (417 aa)
FADDFAS-associated death domain protein. (139 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (829 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10 isoform B. (1354 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (840 aa)
TIAM2T-lymphoma invasion and metastasis-inducing protein 2 isoform A. (1670 aa)
AV530_011470Uncharacterized protein. (92 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (457 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3 isoform A. (564 aa)
AV530_017808Ubiquitin carboxyl-terminal hydrolase. (587 aa)
AV530_009507PH domain-containing protein. (249 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17. (1015 aa)
AV530_011480Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (249 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (334 aa)
AKAP13A-kinase anchor protein 13 isoform D. (2716 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.