(60 nodes) Nucleotide excision repair network (Patagioenas fasciata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (646 aa)
	RFC2	Replication factor C subunit 2. (355 aa)
	ERCC4	DNA repair endonuclease XPF. (961 aa)
	RFC4	Replication factor C subunit 4. (362 aa)
	ERCC3	TFIIH basal transcription factor complex helicase XPB subunit. (780 aa)
	AV530_014737	HELICc2 domain-containing protein. (147 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	DDX11	Putative ATP-dependent RNA helicase DDX11 isoform A. (1346 aa)
	MNAT1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	RPA3	Replication protein A subunit. (121 aa)
	ZNF608	Zinc finger protein 608. (1503 aa)
	DDB2	DNA damage-binding protein 2 isoform B. (516 aa)
	POLD2	DNA polymerase delta subunit 2. (407 aa)
	OBFC1	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (377 aa)
	ERCC6	DNA excision repair protein ERCC-6. (1554 aa)
	POLD3	DNA polymerase delta subunit 3 isoform B. (405 aa)
	RFC5	Replication factor C subunit 5. (255 aa)
	AV530_007031	Uncharacterized protein. (93 aa)
	CDK7	Cyclin-dependent kinase 7. (226 aa)
	CHRAC1	Chromatin accessibility complex protein 1. (135 aa)
	AV530_008697	Protein kinase domain-containing protein. (86 aa)
	AV530_017641	HELICc2 domain-containing protein. (68 aa)
	POLE2	DNA polymerase epsilon subunit 2. (315 aa)
	AV530_007135	DNA_pol_E_B domain-containing protein. (226 aa)
	AV530_017627	UBA domain-containing protein. (117 aa)
	GTF2H4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (320 aa)
	AV530_003887	CULLIN_2 domain-containing protein; Belongs to the cullin family. (614 aa)
	AV530_003886	Cullin domain-containing protein; Belongs to the cullin family. (200 aa)
	AV530_012303	Cyclin-dependent kinase 20-like. (269 aa)
	ATAD5	ATPase family AAA domain-containing protein 5. (1801 aa)
	MEIOB	Meiosis-specific with OB domain-containing protein isoform B. (493 aa)
	ERCC8	DNA excision repair protein ERCC-8 isoform B. (434 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	RAD23B	UV excision repair RAD23-like protein B. (400 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2276 aa)
	CUL4A	Cullin-4A; Belongs to the cullin family. (770 aa)
	ERCC5	DNA repair protein complementing XP-G cells. (1128 aa)
	XPA	DNA repair protein complementing XP-A cells. (180 aa)
	NAIP	Baculoviral IAP repeat-containing protein 1. (1198 aa)
	POLE3	DNA polymerase epsilon subunit 3. (171 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1. (108 aa)
	RFC1	Replication factor C subunit 1. (1150 aa)
	CLSPN	Claspin isoform A. (1258 aa)
	XPC	DNA repair protein complementing XP-C cells. (959 aa)
	RPA2	Replication protein A subunit. (271 aa)
	GTF2H5	General transcription factor IIH subunit 5. (103 aa)
	GTF3C6	General transcription factor 3C polypeptide 6 isoform A. (221 aa)
	GTF2H1	General transcription factor IIH subunit 1. (581 aa)
	AV530_013466	Uncharacterized protein. (130 aa)
	DDB1	DNA damage-binding protein 1. (1140 aa)
	GTF2H3	General transcription factor IIH subunit 3. (307 aa)
	CCNH	Cyclin-H; Belongs to the cyclin family. (321 aa)
	AV530_011963	Caltractin-like. (171 aa)
	ERCC2	TFIIH basal transcription factor complex helicase XPD subunit. (198 aa)
	PPIL3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
	FBXO18	F-box only protein 18. (1002 aa)
	SASS6	Spindle assembly abnormal 6-like protein. (658 aa)
	AV530_004707	CBFD_NFYB_HMF domain-containing protein. (70 aa)
	CCDC94	Coiled-coil domain-containing protein 94. (294 aa)
	PRKRIP1	PRKR-interacting protein 1. (189 aa)

Your Current Organism:

Patagioenas fasciata

NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	AV530_003886	A0A1V4KX51	A0A1V4KYU7	ATPase family AAA domain-containing protein 5.	Cullin domain-containing protein; Belongs to the cullin family.	0.601
ATAD5	AV530_003887	A0A1V4KX51	A0A1V4KYZ1	ATPase family AAA domain-containing protein 5.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.601
ATAD5	AV530_004707	A0A1V4KX51	A0A1V4JZD4	ATPase family AAA domain-containing protein 5.	CBFD_NFYB_HMF domain-containing protein.	0.720
ATAD5	AV530_007031	A0A1V4KX51	A0A1V4KN60	ATPase family AAA domain-containing protein 5.	Uncharacterized protein.	0.759
ATAD5	AV530_007135	A0A1V4KX51	A0A1V4L075	ATPase family AAA domain-containing protein 5.	DNA_pol_E_B domain-containing protein.	0.780
ATAD5	AV530_013466	A0A1V4KX51	A0A1V4JPW5	ATPase family AAA domain-containing protein 5.	Uncharacterized protein.	0.484
ATAD5	AV530_014737	A0A1V4KX51	A0A1V4K9E1	ATPase family AAA domain-containing protein 5.	HELICc2 domain-containing protein.	0.642
ATAD5	AV530_017627	A0A1V4KX51	A0A1V4L005	ATPase family AAA domain-containing protein 5.	UBA domain-containing protein.	0.475
ATAD5	AV530_017641	A0A1V4KX51	A0A1V4L1B1	ATPase family AAA domain-containing protein 5.	HELICc2 domain-containing protein.	0.642
ATAD5	CLSPN	A0A1V4KX51	A0A1V4JHU8	ATPase family AAA domain-containing protein 5.	Claspin isoform A.	0.847
ATAD5	CUL4A	A0A1V4KX51	A0A1V4J3P5	ATPase family AAA domain-containing protein 5.	Cullin-4A; Belongs to the cullin family.	0.601
ATAD5	DDB1	A0A1V4KX51	A0A1V4JQX0	ATPase family AAA domain-containing protein 5.	DNA damage-binding protein 1.	0.620
ATAD5	DDB2	A0A1V4KX51	A0A1V4KET1	ATPase family AAA domain-containing protein 5.	DNA damage-binding protein 2 isoform B.	0.504
ATAD5	DDX11	A0A1V4KX51	A0A1V4K9M8	ATPase family AAA domain-containing protein 5.	Putative ATP-dependent RNA helicase DDX11 isoform A.	0.807
ATAD5	ERCC2	A0A1V4KX51	A0A1V4JVI3	ATPase family AAA domain-containing protein 5.	TFIIH basal transcription factor complex helicase XPD subunit.	0.642
ATAD5	ERCC4	A0A1V4KX51	A0A1V4K4P2	ATPase family AAA domain-containing protein 5.	DNA repair endonuclease XPF.	0.709
ATAD5	ERCC5	A0A1V4KX51	A0A1V4J3U4	ATPase family AAA domain-containing protein 5.	DNA repair protein complementing XP-G cells.	0.808
ATAD5	FBXO18	A0A1V4KX51	A0A1V4JWB4	ATPase family AAA domain-containing protein 5.	F-box only protein 18.	0.726
ATAD5	GTF2H1	A0A1V4KX51	A0A1V4JNS2	ATPase family AAA domain-containing protein 5.	General transcription factor IIH subunit 1.	0.610
ATAD5	MEIOB	A0A1V4KX51	A0A1V4KSK9	ATPase family AAA domain-containing protein 5.	Meiosis-specific with OB domain-containing protein isoform B.	0.838