STRINGSTRING
CACNG2 CACNG2 CREB1 CREB1 AV530_008988 AV530_008988 PIK3R5 PIK3R5 MFSD6L MFSD6L AV530_009659 AV530_009659 ATP1B4 ATP1B4 AGTR2 AGTR2 ATP2B4 ATP2B4 GNAI3 GNAI3 PRKCA PRKCA MAPK14 MAPK14 TPM4 TPM4 AV530_018984 AV530_018984 CACNG1 CACNG1 CACNG5 CACNG5 CACNG4 CACNG4 ADRA1B ADRA1B ADCY8 ADCY8 AV530_008197 AV530_008197 CAMK2A CAMK2A CACNG3 CACNG3 ADRB2 ADRB2 AV530_007944 AV530_007944 ADCY9 ADCY9 AV530_000286 AV530_000286 CREB3L3 CREB3L3 AV530_019715 AV530_019715 ATP2B1 ATP2B1 ADCY3 ADCY3 PTRHD1 PTRHD1 AV530_011548 AV530_011548 AV530_011549 AV530_011549 CREM CREM SCN5A SCN5A AV530_011713 AV530_011713 MYH7B MYH7B ADRA1A ADRA1A CAMK2G CAMK2G ADRB1 ADRB1 PPP2R2A PPP2R2A PPP2R2D PPP2R2D AV530_004041 AV530_004041 AV530_004861 AV530_004861 PPP2R3C PPP2R3C SLC8A3 SLC8A3 CREB3L1 CREB3L1 MYL3 MYL3 AV530_000398 AV530_000398 CACNA1S CACNA1S CREB5 CREB5 SLC39A12 SLC39A12 CACNB2 CACNB2 PPP2R5D PPP2R5D AV530_009991 AV530_009991 SLC8A1 SLC8A1 RPS6KA5 RPS6KA5 AKT1 AKT1 PPP2R5C PPP2R5C PPP2R5E PPP2R5E CACNA2D3 CACNA2D3 CACNA1D CACNA1D CACNA2D2 CACNA2D2 TNNC1 TNNC1 GNAI2 GNAI2 AV530_002801 AV530_002801 AV530_010932 AV530_010932 AV530_010854 AV530_010854 RAPGEF4 RAPGEF4 AV530_010856 AV530_010856 CACNA1C CACNA1C CREB3L2 CREB3L2 PPP1R1C PPP1R1C ATF2 ATF2 AV530_016381 AV530_016381 ADCY5 ADCY5 CACNB4 CACNB4 ATP2A3 ATP2A3 PPP2R3A PPP2R3A MAPK12 MAPK12 MAPK11 MAPK11 ADCY7 ADCY7 PIK3CG PIK3CG AV530_000101 AV530_000101 CACNA2D1 CACNA2D1 TPM3 TPM3 AV530_006914 AV530_006914 AV530_006917 AV530_006917 AV530_015540 AV530_015540 PRKACB PRKACB BCL2 BCL2 AV530_008567 AV530_008567 ADCY2 ADCY2 ATP2B2 ATP2B2 AV530_017131 AV530_017131 ADCY6 ADCY6 AV530_004161 AV530_004161 ADCY1 ADCY1 PPP2R1A PPP2R1A AV530_002806 AV530_002806 AV530_019789 AV530_019789 CAMK2D CAMK2D TPM2 TPM2 CREB3 CREB3 ATP2A2 ATP2A2 PPP1CC PPP1CC AV530_016114 AV530_016114 AV530_001572 AV530_001572 AV530_001297 AV530_001297 AV530_007777 AV530_007777 PLCB2 PLCB2 AV530_013434 AV530_013434 PPP1CA PPP1CA TNNT3 TNNT3 KCNQ1 KCNQ1 AGT AGT AKT3 AKT3 RYR2 RYR2 ADRA1D ADRA1D AV530_007892 AV530_007892 AV530_007882 AV530_007882 AV530_017669 AV530_017669 PPP1CB PPP1CB AV530_018824 AV530_018824 PPP2R5A PPP2R5A AV530_007889 AV530_007889 AV530_007893 AV530_007893 AV530_007883 AV530_007883 AV530_007891 AV530_007891 AV530_007887 AV530_007887 AV530_007886 AV530_007886 AV530_007884 AV530_007884 AV530_007888 AV530_007888 AV530_006876 AV530_006876 AV530_002802 AV530_002802 PPP2R2C PPP2R2C CALML4 CALML4 ATF1 ATF1 RAPGEF3 RAPGEF3 SLC9A1 SLC9A1 PPP2R3B PPP2R3B ATF4 ATF4 SCN4B SCN4B AV530_018224 AV530_018224 AV530_009545 AV530_009545 ATP1B1 ATP1B1 MYH15 MYH15 ATP1A1 ATP1A1 TNNI1 TNNI1 KCNE1 KCNE1 TNNT2 TNNT2 PLCB1 PLCB1 PLCB4 PLCB4
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (303 aa)
AV530_008988Uncharacterized protein. (111 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5. (881 aa)
MFSD6LMajor facilitator superfamily domain-containing protein 6-like. (655 aa)
AV530_009659Myosin-6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2241 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
AGTR2Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (372 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1245 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
MAPK14Mitogen-activated protein kinase. (380 aa)
TPM4Tropomyosin alpha-4 chain isoform B; Belongs to the tropomyosin family. (284 aa)
AV530_018984Mitogen-activated protein kinase. (365 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (226 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (345 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
ADRA1BAlpha-1B adrenergic receptor. (282 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
AV530_008197Serine/threonine-protein phosphatase. (309 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform B; Belongs to the protein kinase superfamily. (489 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
ADRB2Beta-2 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa)
AV530_007944Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (277 aa)
ADCY9Adenylate cyclase type 9 isoform C; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1307 aa)
AV530_000286Uncharacterized protein. (84 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform B. (450 aa)
AV530_019715Uncharacterized protein; Belongs to the tropomyosin family. (256 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1188 aa)
ADCY3Adenylate cyclase type 3 isoform C. (1346 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (125 aa)
AV530_011548Uncharacterized protein. (477 aa)
AV530_011549Uncharacterized protein. (278 aa)
CREMcAMP-responsive element modulator isoform A. (387 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1866 aa)
AV530_011713Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1564 aa)
MYH7BMyosin-7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
ADRA1AAlpha-1A adrenergic receptor. (464 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform E. (553 aa)
ADRB1Beta-1 adrenergic receptor. (380 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (502 aa)
AV530_004041Protein kinase domain-containing protein. (374 aa)
AV530_004861Uncharacterized protein. (379 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (450 aa)
SLC8A3Sodium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (981 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1 isoform B. (506 aa)
MYL3Myosin light chain 3. (193 aa)
AV530_000398Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1362 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1889 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform B. (524 aa)
SLC39A12Zinc transporter ZIP12 isoform F. (666 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform A. (598 aa)
PPP2R5DSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (617 aa)
AV530_009991Calmodulin; Belongs to the calmodulin family. (195 aa)
SLC8A1Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1000 aa)
RPS6KA5Ribosomal protein S6 kinase. (789 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (577 aa)
PPP2R5ESerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (564 aa)
CACNA2D3Voltage-dependent calcium channel subunit alpha-2/delta-3 isoform B. (1109 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2122 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2. (1330 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
AV530_002801Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (539 aa)
AV530_010932Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (636 aa)
AV530_010854Uncharacterized protein. (750 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4 isoform C. (1026 aa)
AV530_010856VGCC_alpha2 domain-containing protein. (238 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2198 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (659 aa)
PPP1R1CProtein phosphatase 1 regulatory subunit 1C. (164 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform B. (569 aa)
AV530_016381Myosin_tail_1 domain-containing protein. (158 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1219 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform A. (527 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1048 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha. (1143 aa)
MAPK12Mitogen-activated protein kinase. (393 aa)
MAPK11Mitogen-activated protein kinase. (335 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1128 aa)
AV530_000101Uncharacterized protein. (339 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform C. (1101 aa)
TPM3Tropomyosin alpha-3 chain isoform C; Belongs to the tropomyosin family. (267 aa)
AV530_006914BZIP domain-containing protein. (296 aa)
AV530_006917Uncharacterized protein. (91 aa)
AV530_015540Uncharacterized protein. (113 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (375 aa)
BCL2Apoptosis regulator Bcl-2. (235 aa)
AV530_008567Calmodulin, striated muscle; Belongs to the calmodulin family. (149 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1257 aa)
AV530_017131Uncharacterized protein. (77 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
AV530_004161SH3 domain-containing protein. (476 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform isoform A. (474 aa)
AV530_002806Uncharacterized protein. (141 aa)
AV530_019789Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (227 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform D. (514 aa)
TPM2Tropomyosin beta chain isoform C; Belongs to the tropomyosin family. (311 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (460 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1014 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (595 aa)
AV530_016114Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (576 aa)
AV530_001572RIH_assoc domain-containing protein. (132 aa)
AV530_001297SH3 domain-containing protein. (607 aa)
AV530_007777Cation_ATPase_C domain-containing protein. (199 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
AV530_013434Uncharacterized protein. (294 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
TNNT3Troponin T, fast skeletal muscle. (497 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1 isoform C; Belongs to the potassium channel family. (717 aa)
AGTAngiotensinogen; Belongs to the serpin family. (463 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RYR2Ryanodine receptor 2 isoform B. (4819 aa)
ADRA1DAlpha-1D adrenergic receptor. (511 aa)
AV530_007892Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (583 aa)
AV530_007882Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (808 aa)
AV530_017669Uncharacterized protein. (123 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (418 aa)
AV530_018824Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
PPP2R5ASerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (476 aa)
AV530_007889Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (160 aa)
AV530_007893Myosin-3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1893 aa)
AV530_007883Myosin_tail_1 domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (292 aa)
AV530_007891Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (547 aa)
AV530_007887Myosin_tail_1 domain-containing protein. (167 aa)
AV530_007886Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2062 aa)
AV530_007884Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (818 aa)
AV530_007888Uncharacterized protein. (110 aa)
AV530_006876Uncharacterized protein. (76 aa)
AV530_002802Cation_ATPase_C domain-containing protein. (121 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
CALML4Calmodulin-like protein 4. (153 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (306 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (763 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (802 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform B. (581 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (357 aa)
SCN4BSodium channel subunit beta-4. (233 aa)
AV530_018224Uncharacterized protein. (127 aa)
AV530_009545Ion_trans domain-containing protein. (134 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (282 aa)
MYH15Myosin-15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1024 aa)
TNNI1Troponin I, slow skeletal muscle. (172 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (126 aa)
TNNT2Troponin T, cardiac muscle. (324 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1268 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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