STRINGSTRING
AV530_004017 AV530_004017 PLK3 PLK3 PIK3R3 PIK3R3 AV530_008567 AV530_008567 AV530_004016 AV530_004016 AV530_019789 AV530_019789 MAPK10 MAPK10 AV530_011960 AV530_011960 PPP3CA PPP3CA NFKB1 NFKB1 PTPN11 PTPN11 AV530_013536 AV530_013536 RRAS2 RRAS2 LSP1 LSP1 HRAS HRAS AKT3 AKT3 AV530_018824 AV530_018824 MAP3K14 MAP3K14 FCER1G FCER1G MALT1 MALT1 KRAS KRAS CALML4 CALML4 IL23A IL23A CLEC4C CLEC4C TMEM52B TMEM52B CARD9 CARD9 SYK SYK CBLB CBLB ITPR2 ITPR2 PPP3R1 PPP3R1 REL REL MAPK9 MAPK9 IL12B-2 IL12B-2 AV530_018984 AV530_018984 MAPK14 MAPK14 CSDE1 CSDE1 ITPR3 ITPR3 RHOC RHOC MAPKAPK2 MAPKAPK2 NRAS NRAS AV530_010984 AV530_010984 PIK3R1 PIK3R1 MRAS MRAS MDM2 MDM2 AV530_004193 AV530_004193 AV530_004298 AV530_004298 AV530_002910 AV530_002910 CHUK CHUK IL12B IL12B AV530_004299 AV530_004299 AKT1 AKT1 AV530_009991 AV530_009991 PIK3CB PIK3CB IL6 IL6 NFATC2 NFATC2 NFATC1 NFATC1 AV530_016372 AV530_016372 NFKBIA NFKBIA AV530_003980 AV530_003980 IL1B IL1B IKBKB IKBKB EGR3 EGR3 MAPK8 MAPK8 NFKB2 NFKB2 PPP3CC PPP3CC PPP3CB PPP3CB REM1 REM1 SRC SRC IL12A IL12A AV530_011288 AV530_011288 PIK3CD PIK3CD PIK3R2 PIK3R2 AV530_008875 AV530_008875 IRF1 IRF1 PIK3CA PIK3CA RAF1 RAF1 MAPK12 MAPK12 MAPK11 MAPK11 CYLD CYLD PLCG2 PLCG2 RRAD RRAD AV530_004700 AV530_004700 PTGS2 PTGS2 BCL10 BCL10 JUN JUN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AV530_004017Caspase-8; Belongs to the peptidase C14A family. (490 aa)
PLK3Serine/threonine-protein kinase PLK. (643 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform A. (731 aa)
AV530_008567Calmodulin, striated muscle; Belongs to the calmodulin family. (149 aa)
AV530_004016Caspase-8; Belongs to the peptidase C14A family. (373 aa)
AV530_019789Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (227 aa)
MAPK10Mitogen-activated protein kinase. (540 aa)
AV530_011960Interleukin; Belongs to the IL-15/IL-21 family. (133 aa)
PPP3CASerine/threonine-protein phosphatase. (510 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform B. (1044 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (581 aa)
AV530_013536NACHT, LRR and PYD domains-containing protein 12. (958 aa)
RRAS2Ras-related protein R-Ras2. (203 aa)
LSP1Lymphocyte-specific protein 1 isoform A. (358 aa)
HRASGTPase HRas. (184 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
AV530_018824Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (941 aa)
FCER1GFc of IgE, high affinity I, receptor for gamma polypeptide. (89 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform B. (770 aa)
KRASGTPase KRas isoform A. (192 aa)
CALML4Calmodulin-like protein 4. (153 aa)
IL23AInterleukin-23 subunit alpha. (180 aa)
CLEC4CC-type lectin domain family 4 member C. (229 aa)
TMEM52BTransmembrane protein 52B. (191 aa)
CARD9Caspase recruitment domain-containing protein 9 isoform A. (720 aa)
SYKTyrosine-protein kinase SYK. (652 aa)
CBLBE3 ubiquitin-protein ligase CBL-B. (1023 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform A. (2724 aa)
PPP3R1Calcineurin subunit B type 1 isoform B. (213 aa)
RELProto-oncogene c-Rel. (573 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
IL12B-2Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (484 aa)
AV530_018984Mitogen-activated protein kinase. (365 aa)
MAPK14Mitogen-activated protein kinase. (380 aa)
CSDE1Cold shock domain-containing protein E1. (1129 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
RHOCRho-related GTP-binding protein RhoC. (196 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa)
NRASGTPase NRas. (189 aa)
AV530_010984MALT1_Ig domain-containing protein. (175 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (746 aa)
MRASRas-related protein M-Ras. (333 aa)
MDM2E3 ubiquitin-protein ligase Mdm2 isoform B. (542 aa)
AV530_004193Uncharacterized protein. (394 aa)
AV530_004298Uncharacterized protein. (1851 aa)
AV530_002910Uncharacterized protein. (209 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (1038 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (243 aa)
AV530_004299Uncharacterized protein. (1051 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
AV530_009991Calmodulin; Belongs to the calmodulin family. (195 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1118 aa)
IL6Interleukin-6. (150 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform A. (927 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1 isoform A. (927 aa)
AV530_016372Hepatic lectin. (208 aa)
NFKBIANF-kappa-B inhibitor alpha. (313 aa)
AV530_003980Transcription factor RelB-like protein. (109 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (269 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (757 aa)
EGR3Early growth response protein 3. (423 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit. (934 aa)
PPP3CCSerine/threonine-protein phosphatase. (566 aa)
PPP3CBSerine/threonine-protein phosphatase. (520 aa)
REM1GTP-binding protein REM 1. (292 aa)
SRCTyrosine-protein kinase. (585 aa)
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (162 aa)
AV530_011288Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
AV530_008875Ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (749 aa)
IRF1Interferon regulatory factor. (305 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform A. (698 aa)
MAPK12Mitogen-activated protein kinase. (393 aa)
MAPK11Mitogen-activated protein kinase. (335 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD isoform B; Belongs to the peptidase C19 family. (954 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1216 aa)
RRADGTP-binding protein RAD. (328 aa)
AV530_004700Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (849 aa)
PTGS2Prostaglandin G/H synthase 2. (603 aa)
BCL10B-cell lymphoma/leukemia 10. (242 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (314 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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