STRINGSTRING
PLA2G4F PLA2G4F SOS1 SOS1 PLCB4 PLCB4 PLCB1 PLCB1 MAP2K4 MAP2K4 ITPR2 ITPR2 AV530_000265 AV530_000265 AV530_009545 AV530_009545 PTK2B PTK2B ATF4 ATF4 ELK3 ELK3 AV530_019451 AV530_019451 CALML4 CALML4 MAP2K1 MAP2K1 KRAS KRAS AV530_019514 AV530_019514 AV530_018824 AV530_018824 MAP3K4 MAP3K4 CGA CGA HRAS HRAS FSHB FSHB PLCB2 PLCB2 AV530_001420 AV530_001420 MAPK1 MAPK1 CAMK2D CAMK2D MAPK10 MAPK10 ADCY1 ADCY1 ADCY6 ADCY6 AV530_009265 AV530_009265 ADCY2 ADCY2 AV530_008567 AV530_008567 JUN JUN PRKACB PRKACB PLA2G4A PLA2G4A RRAD RRAD MMP2 MMP2 ADCY7 ADCY7 MAPK11 MAPK11 MAPK12 MAPK12 RAF1 RAF1 PLD1 PLD1 ADCY5 ADCY5 MAP3K2 MAP3K2 CACNA1C CACNA1C AV530_004298 AV530_004298 CACNA1D CACNA1D AV530_004299 AV530_004299 AV530_009991 AV530_009991 AV530_014098 AV530_014098 GNAQ GNAQ AV530_007127 AV530_007127 AV530_007128 AV530_007128 NRAS NRAS ITPR3 ITPR3 PRKCA PRKCA CSDE1 CSDE1 MAPK14 MAPK14 AV530_018984 AV530_018984 GRB2 GRB2 MAP2K6 MAP2K6 ADCY8 ADCY8 HBEGF HBEGF CAMK2A CAMK2A MAPK9 MAPK9 AV530_017766 AV530_017766 EGR1 EGR1 ADCY9 ADCY9 PRKCB PRKCB MAP2K3 MAP2K3 MAP3K1 MAP3K1 CDC42 CDC42 AV530_006700 AV530_006700 MAP2K2 MAP2K2 ADCY3 ADCY3 PTRHD1 PTRHD1 PTX3 PTX3 AV530_011700 AV530_011700 SRC SRC REM1 REM1 CAMK2G CAMK2G MAPK8 MAPK8 GNRH1 GNRH1 AV530_004041 AV530_004041 AV530_010426 AV530_010426 AV530_004861 AV530_004861 AV530_010422 AV530_010422 AV530_010424 AV530_010424 AV530_010423 AV530_010423 JMJD7 JMJD7 AV530_010417 AV530_010417 AV530_010421 AV530_010421 CACNA1S CACNA1S AV530_010425 AV530_010425 AV530_010418 AV530_010418
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4FPhospholipase A2. (913 aa)
SOS1Son of sevenless-like protein 1. (1345 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1268 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (381 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform A. (2724 aa)
AV530_000265Uncharacterized protein. (319 aa)
AV530_009545Ion_trans domain-containing protein. (134 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform B; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1002 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (357 aa)
ELK3ETS domain-containing protein Elk-3. (422 aa)
AV530_019451Gonadotropin-releasing hormone receptor-like. (409 aa)
CALML4Calmodulin-like protein 4. (153 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
KRASGTPase KRas isoform A. (192 aa)
AV530_019514Gonadotropin-releasing hormone II receptor; Belongs to the G-protein coupled receptor 1 family. (388 aa)
AV530_018824Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4 isoform A. (1561 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
HRASGTPase HRas. (184 aa)
FSHBFollitropin subunit beta. (156 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
AV530_001420Uncharacterized protein. (1006 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (409 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform D. (514 aa)
MAPK10Mitogen-activated protein kinase. (540 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
AV530_009265Uncharacterized protein. (71 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
AV530_008567Calmodulin, striated muscle; Belongs to the calmodulin family. (149 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (314 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (375 aa)
PLA2G4APhospholipase A2. (749 aa)
RRADGTP-binding protein RAD. (328 aa)
MMP2Type IV collagenase. (661 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
MAPK11Mitogen-activated protein kinase. (335 aa)
MAPK12Mitogen-activated protein kinase. (393 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform A. (698 aa)
PLD1Phospholipase. (1365 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1219 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (624 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2198 aa)
AV530_004298Uncharacterized protein. (1851 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2122 aa)
AV530_004299Uncharacterized protein. (1051 aa)
AV530_009991Calmodulin; Belongs to the calmodulin family. (195 aa)
AV530_014098Uncharacterized protein. (213 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (320 aa)
AV530_007127DH domain-containing protein. (370 aa)
AV530_007128Ras-GEF domain-containing protein. (352 aa)
NRASGTPase NRas. (189 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
CSDE1Cold shock domain-containing protein E1. (1129 aa)
MAPK14Mitogen-activated protein kinase. (380 aa)
AV530_018984Mitogen-activated protein kinase. (365 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
HBEGFProheparin-binding EGF-like growth factor. (272 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform B; Belongs to the protein kinase superfamily. (489 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
AV530_017766Uncharacterized protein. (114 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (510 aa)
ADCY9Adenylate cyclase type 9 isoform C; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1307 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3 isoform B; Belongs to the protein kinase superfamily. (348 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1 isoform A. (1375 aa)
CDC42Cell division control 42-like protein isoform A. (191 aa)
AV530_006700Guanine nucleotide-binding protein subunit alpha-11. (350 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (398 aa)
ADCY3Adenylate cyclase type 3 isoform C. (1346 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (125 aa)
PTX3Pentraxin-related protein PTX3. (424 aa)
AV530_011700Mitogen-activated protein kinase kinase kinase 3. (621 aa)
SRCTyrosine-protein kinase. (585 aa)
REM1GTP-binding protein REM 1. (292 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform E. (553 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
GNRH1Progonadoliberin-1. (91 aa)
AV530_004041Protein kinase domain-containing protein. (374 aa)
AV530_010426Phospholipase A2. (1257 aa)
AV530_004861Uncharacterized protein. (379 aa)
AV530_010422Phospholipase A2. (692 aa)
AV530_010424Cytosolic phospholipase A2 epsilon-like. (710 aa)
AV530_010423Phospholipase A2. (856 aa)
JMJD7JmjC domain-containing protein 7. (317 aa)
AV530_010417Phospholipase A2. (700 aa)
AV530_010421Cytosolic phospholipase A2 epsilon. (649 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1889 aa)
AV530_010425Phospholipase A2. (799 aa)
AV530_010418PLA2c domain-containing protein. (203 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.