(7 nodes) Serine/threonine-protein kinase N, first HR1 domain, and Rho Binding network (Aotus nancymaae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RHOB	Ras homolog family member B. (196 aa)
	RHOC	Ras homolog family member C. (193 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
	PKN1	Protein kinase N1. (954 aa)
	PKN2	Protein kinase N2. (983 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
	PKN3	Protein kinase N3. (879 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PKN1	PKN2	ENSANAP00000025687	ENSANAP00000027807	Protein kinase N1.	Protein kinase N2.	0.908
PKN1	PKN3	ENSANAP00000025687	ENSANAP00000032945	Protein kinase N1.	Protein kinase N3.	0.906
PKN1	RHOB	ENSANAP00000025687	ENSANAP00000002366	Protein kinase N1.	Ras homolog family member B.	0.943
PKN1	RHOC	ENSANAP00000025687	ENSANAP00000005709	Protein kinase N1.	Ras homolog family member C.	0.977
PKN1	ROCK1	ENSANAP00000025687	ENSANAP00000032501	Protein kinase N1.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.434
PKN1	ROCK2	ENSANAP00000025687	ENSANAP00000021535	Protein kinase N1.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.489
PKN2	PKN1	ENSANAP00000027807	ENSANAP00000025687	Protein kinase N2.	Protein kinase N1.	0.908
PKN2	PKN3	ENSANAP00000027807	ENSANAP00000032945	Protein kinase N2.	Protein kinase N3.	0.906
PKN2	RHOB	ENSANAP00000027807	ENSANAP00000002366	Protein kinase N2.	Ras homolog family member B.	0.886
PKN2	RHOC	ENSANAP00000027807	ENSANAP00000005709	Protein kinase N2.	Ras homolog family member C.	0.936
PKN2	ROCK1	ENSANAP00000027807	ENSANAP00000032501	Protein kinase N2.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.460
PKN2	ROCK2	ENSANAP00000027807	ENSANAP00000021535	Protein kinase N2.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.664
PKN3	PKN1	ENSANAP00000032945	ENSANAP00000025687	Protein kinase N3.	Protein kinase N1.	0.906
PKN3	PKN2	ENSANAP00000032945	ENSANAP00000027807	Protein kinase N3.	Protein kinase N2.	0.906
PKN3	RHOB	ENSANAP00000032945	ENSANAP00000002366	Protein kinase N3.	Ras homolog family member B.	0.791
PKN3	RHOC	ENSANAP00000032945	ENSANAP00000005709	Protein kinase N3.	Ras homolog family member C.	0.812
PKN3	ROCK1	ENSANAP00000032945	ENSANAP00000032501	Protein kinase N3.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.511
PKN3	ROCK2	ENSANAP00000032945	ENSANAP00000021535	Protein kinase N3.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.511
RHOB	PKN1	ENSANAP00000002366	ENSANAP00000025687	Ras homolog family member B.	Protein kinase N1.	0.943
RHOB	PKN2	ENSANAP00000002366	ENSANAP00000027807	Ras homolog family member B.	Protein kinase N2.	0.886