STRINGSTRING
SMAD3 SMAD3 TGFBR3 TGFBR3 SMAD9 SMAD9 INHBE INHBE INHA INHA ACVR1C ACVR1C SMAD6 SMAD6 SKI SKI INHBA INHBA TGFBR1 TGFBR1 SKIL SKIL SMAD4 SMAD4 TGFBR2 TGFBR2 FST FST SMAD7 SMAD7 ACVR1B ACVR1B TGFB3 TGFB3 INHBB INHBB INHBC INHBC ACVR2A ACVR2A MSTN MSTN SMAD2 SMAD2 SMURF1 SMURF1 TGFB2 TGFB2 GDF11 GDF11 ZFYVE16 ZFYVE16 ACVR2B ACVR2B SMURF2 SMURF2 ZFYVE9 ZFYVE9 TGFB1 TGFB1 SMAD1 SMAD1 SMAD5 SMAD5 FSTL3 FSTL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
INHBEInhibin subunit beta E. (350 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (365 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
SMAD6Mothers against decapentaplegic homolog. (494 aa)
SKISKI proto-oncogene. (726 aa)
INHBAInhibin subunit beta A. (426 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
SKILSKI like proto-oncogene. (684 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
FSTFollistatin. (344 aa)
SMAD7Mothers against decapentaplegic homolog. (489 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (545 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
INHBBInhibin subunit beta B. (400 aa)
INHBCInhibin subunit beta C. (352 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
MSTNMyostatin. (380 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GDF11Growth differentiation factor 11. (407 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1539 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
SMURF2E3 ubiquitin-protein ligase. (736 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1425 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (378 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
FSTL3Follistatin like 3. (263 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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