STRINGSTRING
FNIP2 FNIP2 CAB39 CAB39 HUNK HUNK ENSANAP00000002754 ENSANAP00000002754 TSC1 TSC1 LOC105733215 LOC105733215 LOC105707993 LOC105707993 TSSK6 TSSK6 TRIB1 TRIB1 PDPK1 PDPK1 TSSK3 TSSK3 KIAA1671 KIAA1671 RRAGB RRAGB FLCN FLCN FNIP1 FNIP1 AKT2 AKT2 DEPDC5 DEPDC5 BMT2 BMT2 RHEB RHEB PPM1N PPM1N RRAGD RRAGD LAMTOR3 LAMTOR3 ENSANAP00000011109 ENSANAP00000011109 TSC2 TSC2 AIF1L AIF1L CAB39L CAB39L LOC105719409 LOC105719409 LOC105730229 LOC105730229 DEPTOR DEPTOR RHEBL1 RHEBL1 PIM1 PIM1 PPM1B PPM1B C12orf66 C12orf66 PIM2 PIM2 SLC38A9 SLC38A9 MLST8 MLST8 RPS6KB1 RPS6KB1 LOC105726279 LOC105726279 CAMKK1 CAMKK1 STK40 STK40 SESN1 SESN1 STRADB STRADB AKT1 AKT1 NPRL3 NPRL3 TBC1D7 TBC1D7 SEH1L SEH1L PRKAG1 PRKAG1 TRIB2 TRIB2 RPTOR RPTOR LAMTOR4 LAMTOR4 RPS6KB2 RPS6KB2 CASTOR1 CASTOR1 SESN2 SESN2 STK32C STK32C NPRL2 NPRL2 MTOR MTOR KPTN KPTN ENSANAP00000026451 ENSANAP00000026451 WDR24 WDR24 WDR59 WDR59 PPM1A PPM1A CRYGN CRYGN RRAGA RRAGA MIOS MIOS CAMKK2 CAMKK2 PRKAG3 PRKAG3 SESN3 SESN3 PRKAB2 PRKAB2 ENSANAP00000029587 ENSANAP00000029587 PRKAA1 PRKAA1 DMRTC2 DMRTC2 PRKAB1 PRKAB1 MAP3K15 MAP3K15 RICTOR RICTOR ITFG2 ITFG2 LAMTOR2 LAMTOR2 CALN1 CALN1 STRADA STRADA CASTOR2 CASTOR2 LAMTOR5 LAMTOR5 LAMTOR1 LAMTOR1 AKT1S1 AKT1S1 MAPKAP1 MAPKAP1 CRYBB3 CRYBB3 PRKAA2 PRKAA2 STK11 STK11 RRAGC RRAGC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FNIP2Folliculin interacting protein 2. (1172 aa)
CAB39Calcium binding protein 39. (341 aa)
HUNKProtein kinase domain-containing protein. (714 aa)
ENSANAP00000002754Uncharacterized protein. (121 aa)
TSC1TSC complex subunit 1. (1163 aa)
LOC105733215Uncharacterized protein. (303 aa)
LOC105707993Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (451 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (345 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (572 aa)
TSSK3Testis specific serine kinase 3. (268 aa)
KIAA1671KIAA1671. (1799 aa)
RRAGBRas related GTP binding B. (374 aa)
FLCNFolliculin. (579 aa)
FNIP1Folliculin interacting protein 1. (1166 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
DEPDC5DEP domain-containing protein. (1579 aa)
BMT2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
PPM1NProtein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (429 aa)
RRAGDRas related GTP binding D. (402 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
ENSANAP00000011109Uncharacterized protein. (170 aa)
TSC2TSC complex subunit 2. (1807 aa)
AIF1LAllograft inflammatory factor 1 like. (164 aa)
CAB39LCalcium binding protein 39 like. (337 aa)
LOC105719409Uncharacterized protein; Belongs to the parvalbumin family. (109 aa)
LOC105730229PPM-type phosphatase domain-containing protein. (310 aa)
DEPTORDEP domain containing MTOR interacting protein. (329 aa)
RHEBL1RHEB like 1. (192 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (402 aa)
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
C12orf66Chromosome 12 open reading frame 66. (494 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
MLST8MTOR associated protein, LST8 homolog. (338 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC105726279Protein kinase domain-containing protein. (711 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (576 aa)
STK40Serine/threonine kinase 40. (435 aa)
SESN1Sestrin 1. (551 aa)
STRADBSTE20 related adaptor beta. (423 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
TBC1D7TBC1 domain family member 7. (293 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (422 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (285 aa)
TRIB2Tribbles pseudokinase 2. (371 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1327 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (128 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (483 aa)
CASTOR1Uncharacterized protein. (329 aa)
SESN2Sestrin 2. (480 aa)
STK32CSerine/threonine kinase 32C; Belongs to the protein kinase superfamily. (468 aa)
NPRL2NPR2 like, GATOR1 complex subunit. (381 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
KPTNKaptin, actin binding protein. (397 aa)
ENSANAP00000026451Uncharacterized protein. (356 aa)
WDR24WD repeat domain 24. (914 aa)
WDR59WD repeat domain 59. (942 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (454 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (143 aa)
RRAGAUncharacterized protein. (313 aa)
MIOSMeiosis regulator for oocyte development. (875 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (555 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
SESN3Sestrin 3. (492 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (266 aa)
ENSANAP00000029587Uncharacterized protein. (291 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
DMRTC2DMRT like family C2. (412 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
MAP3K15Mitogen-activated protein kinase kinase kinase 15. (1302 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
ITFG2Integrin alpha FG-GAP repeat containing 2. (444 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (149 aa)
CALN1Calneuron 1. (261 aa)
STRADASTE20 related adaptor alpha. (500 aa)
CASTOR2Uncharacterized protein. (291 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (145 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
AKT1S1AKT1 substrate 1. (276 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
RRAGCRas related GTP binding C. (349 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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