18 items (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	SOX9	SRY-box transcription factor 9. (505 aa)
	ENSANAP00000013693	Uncharacterized protein. (110 aa)
	SCUBE2	Signal peptide, CUB domain and EGF like domain containing 2. (1017 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
	RARG	Retinoic acid receptor gamma. (456 aa)
	ENSANAP00000036701	GRIP domain-containing protein. (1606 aa)
	ATF2	Activating transcription factor 2. (287 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3. (655 aa)
	MATN1	Matrilin 1. (496 aa)
	NPPC	Natriuretic peptide C. (126 aa)
	ANXA6	Annexin. (673 aa)
	ENSANAP00000030329	GRIP domain-containing protein. (402 aa)
	AXIN2	Axin 2. (843 aa)
	TRIP11	Thyroid hormone receptor interactor 11. (1980 aa)
	TSKU	Tsukushi, small leucine rich proteoglycan. (381 aa)
	IFT80	Intraflagellar transport 80. (778 aa)
	SERPINH1	Serpin family H member 1; Belongs to the serpin family. (418 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ENSANAP00000013693	ENSANAP00000039927	ENSANAP00000013693	Activating transcription factor 2.	Uncharacterized protein.	0.857
AXIN2	IHH	ENSANAP00000025255	ENSANAP00000042436	Axin 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.571
ENSANAP00000013693	ATF2	ENSANAP00000013693	ENSANAP00000039927	Uncharacterized protein.	Activating transcription factor 2.	0.857
IHH	AXIN2	ENSANAP00000042436	ENSANAP00000025255	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Axin 2.	0.571
IHH	SOX9	ENSANAP00000042436	ENSANAP00000010675	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	SRY-box transcription factor 9.	0.466
SOX9	IHH	ENSANAP00000010675	ENSANAP00000042436	SRY-box transcription factor 9.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.466