STRINGSTRING
CBX6 CBX6 SYNCRIP SYNCRIP SNRPC-4 SNRPC-4 SRA1 SRA1 DIS3L2 DIS3L2 A1CF A1CF ZCCHC13 ZCCHC13 ENSANAP00000003651 ENSANAP00000003651 ENSANAP00000003594 ENSANAP00000003594 SNRPC-3 SNRPC-3 SNRPC SNRPC LSM14A LSM14A ENSANAP00000002877 ENSANAP00000002877 LACTB2 LACTB2 LOC105732158 LOC105732158 ENSANAP00000002469 ENSANAP00000002469 PABPC4L PABPC4L DLX2 DLX2 ENSANAP00000001377 ENSANAP00000001377 PABPC5 PABPC5 ENSANAP00000015061 ENSANAP00000015061 FXR1 FXR1 TIA1 TIA1 DDX11 DDX11 LOC105720471 LOC105720471 SNRPC-2 SNRPC-2 EIF4A3 EIF4A3 ENSANAP00000017680 ENSANAP00000017680 PABPC1L PABPC1L ILF3 ILF3 FMR1 FMR1 KHDRBS1 KHDRBS1 MSI1 MSI1 LOC105705467 LOC105705467 IGHMBP2 IGHMBP2 AGO2 AGO2 ENSANAP00000019549 ENSANAP00000019549 LOC105727630 LOC105727630 ENSANAP00000020227 ENSANAP00000020227 U2AF2 U2AF2 IFIH1 IFIH1 RBPMS RBPMS MCRS1 MCRS1 PAN3 PAN3 ENSANAP00000005761 ENSANAP00000005761 ENSANAP00000021934 ENSANAP00000021934 DHX58 DHX58 HNRNPDL HNRNPDL ENSANAP00000022689 ENSANAP00000022689 CBX7 CBX7 ENDOV ENDOV CBX4 CBX4 JMJD6 JMJD6 ENSANAP00000037764 ENSANAP00000037764 PUS1 PUS1 DAZAP1 DAZAP1 LOC105705110 LOC105705110 ENSANAP00000036652 ENSANAP00000036652 LARP4 LARP4 LOC105717986 LOC105717986 EIF4H EIF4H ENSANAP00000025204 ENSANAP00000025204 DHX9 DHX9 ENSANAP00000025387 ENSANAP00000025387 LOC105715551 LOC105715551 TLR8 TLR8 CNBP CNBP ELAVL4 ELAVL4 ENSANAP00000026172 ENSANAP00000026172 DDX60 DDX60 AQR AQR ENSANAP00000035642 ENSANAP00000035642 ENSANAP00000035410 ENSANAP00000035410 HNRNPC HNRNPC CBX8 CBX8 RBM11 RBM11 ENSANAP00000032926 ENSANAP00000032926 HNRNPU HNRNPU PPIE PPIE LOC105723312 LOC105723312 PABPC1 PABPC1 LOC110568655 LOC110568655 ADARB2 ADARB2 ENSANAP00000030478 ENSANAP00000030478 ZC3H14 ZC3H14 DDX60L DDX60L LOC105730848 LOC105730848 DDX58 DDX58 RBM7 RBM7 AGO4 AGO4 ENSANAP00000027070 ENSANAP00000027070 ENSANAP00000027062 ENSANAP00000027062 LOC105729974 LOC105729974 EXOSC10 EXOSC10 TLR7 TLR7 RBMS1 RBMS1 KHDRBS2 KHDRBS2 PABPC4 PABPC4 ENSANAP00000014629 ENSANAP00000014629 LONP1 LONP1 PNPT1 PNPT1 PATL1 PATL1 ENSANAP00000008200 ENSANAP00000008200 EIF4B EIF4B SNRPC-6 SNRPC-6 LOC105707075 LOC105707075 SNRPC-5 SNRPC-5 PTBP1 PTBP1 RBMS2 RBMS2 LOC105718527 LOC105718527 DDX1 DDX1 MSI2 MSI2 AGO3 AGO3 AGO1 AGO1 POLR2G POLR2G
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBX6Chromobox 6. (413 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (623 aa)
SNRPC-4U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (171 aa)
SRA1Steroid receptor RNA activator 1. (236 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (880 aa)
A1CFAPOBEC1 complementation factor. (602 aa)
ZCCHC13Zinc finger CCHC-type containing 13. (151 aa)
ENSANAP00000003651Uncharacterized protein. (72 aa)
ENSANAP00000003594Uncharacterized protein. (71 aa)
SNRPC-3U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (163 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (180 aa)
LSM14AUncharacterized protein. (484 aa)
ENSANAP00000002877Uncharacterized protein. (540 aa)
LACTB2Lactamase beta 2. (288 aa)
LOC105732158U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
ENSANAP00000002469RRM domain-containing protein. (250 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (427 aa)
DLX2Distal-less homeobox 2. (328 aa)
ENSANAP00000001377Uncharacterized protein. (71 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
ENSANAP00000015061AXH domain-containing protein. (662 aa)
FXR1FMR1 autosomal homolog 1. (699 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
DDX11DEAD/H-box helicase 11. (925 aa)
LOC105720471RRM domain-containing protein. (515 aa)
SNRPC-2U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
ENSANAP00000017680Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (605 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
ILF3Interleukin enhancer binding factor 3. (898 aa)
FMR1Fragile X mental retardation 1. (632 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (443 aa)
MSI1Musashi RNA binding protein 1. (364 aa)
LOC105705467Uncharacterized protein. (375 aa)
IGHMBP2Immunoglobulin mu DNA binding protein 2. (1002 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (859 aa)
ENSANAP00000019549RRM domain-containing protein. (617 aa)
LOC105727630Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (616 aa)
ENSANAP00000020227Uncharacterized protein. (325 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (406 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
RBPMSRNA binding protein, mRNA processing factor. (219 aa)
MCRS1Microspherule protein 1. (475 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (848 aa)
ENSANAP00000005761Uncharacterized protein. (540 aa)
ENSANAP00000021934Uncharacterized protein. (459 aa)
DHX58DExH-box helicase 58. (678 aa)
HNRNPDLUncharacterized protein. (420 aa)
ENSANAP00000022689Uncharacterized protein. (217 aa)
CBX7Chromobox 7. (252 aa)
ENDOVEndonuclease V. (339 aa)
CBX4Chromobox 4. (553 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (452 aa)
ENSANAP00000037764Uncharacterized protein. (522 aa)
PUS1Pseudouridine synthase 1. (326 aa)
DAZAP1DAZ associated protein 1. (407 aa)
LOC105705110Uncharacterized protein. (517 aa)
ENSANAP00000036652Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (558 aa)
LARP4La ribonucleoprotein domain family member 4. (730 aa)
LOC105717986Uncharacterized protein. (539 aa)
EIF4HEukaryotic translation initiation factor 4H. (247 aa)
ENSANAP00000025204Uncharacterized protein. (428 aa)
DHX9DExH-box helicase 9. (1270 aa)
ENSANAP00000025387Uncharacterized protein. (435 aa)
LOC105715551Uncharacterized protein. (143 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1047 aa)
CNBPCCHC-type zinc finger nucleic acid binding protein. (178 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
ENSANAP00000026172RRM domain-containing protein. (421 aa)
DDX60DExD/H-box helicase 60. (1702 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1480 aa)
ENSANAP00000035642Uncharacterized protein. (300 aa)
ENSANAP00000035410RRM domain-containing protein. (232 aa)
HNRNPCRRM domain-containing protein. (306 aa)
CBX8Chromobox 8. (414 aa)
RBM11RNA binding motif protein 11. (238 aa)
ENSANAP00000032926Uncharacterized protein. (371 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (806 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (313 aa)
LOC105723312Uncharacterized protein. (389 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
LOC110568655Uncharacterized protein. (406 aa)
ADARB2Adenosine deaminase RNA specific B2 (inactive). (738 aa)
ENSANAP00000030478B30.2/SPRY domain-containing protein. (605 aa)
ZC3H14Uncharacterized protein. (724 aa)
DDX60LDExD/H-box 60 like. (1641 aa)
LOC105730848RRM domain-containing protein. (578 aa)
DDX58DExD/H-box helicase 58. (855 aa)
RBM7RRM domain-containing protein. (156 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
ENSANAP00000027070Uncharacterized protein. (76 aa)
ENSANAP00000027062RRM domain-containing protein. (156 aa)
LOC105729974DFDF domain-containing protein. (375 aa)
EXOSC10Exosome component 10. (839 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
RBMS1RNA binding motif single stranded interacting protein 1. (322 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (298 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
ENSANAP00000014629AXH domain-containing protein. (892 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (895 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (784 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (770 aa)
ENSANAP00000008200RRM domain-containing protein. (510 aa)
EIF4BRRM domain-containing protein. (616 aa)
SNRPC-6U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (139 aa)
LOC105707075Uncharacterized protein. (519 aa)
SNRPC-5U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (165 aa)
PTBP1Polypyrimidine tract binding protein 1. (557 aa)
RBMS2RNA binding motif single stranded interacting protein 2. (390 aa)
LOC105718527Uncharacterized protein. (290 aa)
DDX1DEAD-box helicase 1. (740 aa)
MSI2Musashi RNA binding protein 2. (328 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (859 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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