(37 nodes) Regulation of cholesterol efflux network (Aotus nancymaae)

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second shell of interactors

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Predicted Interactions

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Your Input:
	EEPD1	Endonuclease/exonuclease/phosphatase family domain containing 1. (569 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (459 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2220 aa)
	LOC105714098	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (537 aa)
	PON1	Paraoxonase 1. (355 aa)
	PLA2G10	Phospholipase A(2). (165 aa)
	ZDHHC8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (750 aa)
	NFKBIA	NFKB inhibitor alpha. (310 aa)
	PTCH1	Patched 1. (1453 aa)
	ABCA5	ATP binding cassette subfamily A member 5. (1590 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (281 aa)
	PLTP	Phospholipid transfer protein. (548 aa)
	CETP	Cholesteryl ester transfer protein. (521 aa)
	ABCA2	ATP binding cassette subfamily A member 2. (2349 aa)
	CAV1	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
	SREBF2	Sterol regulatory element binding transcription factor 2. (1143 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (244 aa)
	ENSANAP00000018437	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (454 aa)
	YJEFN3	YjeF N-terminal domain containing 3. (288 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (603 aa)
	GPS2	G protein pathway suppressor 2. (327 aa)
	TTC39B	Tetratricopeptide repeat domain 39B. (661 aa)
	LAMTOR1	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (452 aa)
	ABCA3	ATP binding cassette subfamily A member 3. (1722 aa)
	SIRT1	Sirtuin 1. (751 aa)
	ENSANAP00000038778	Uncharacterized protein. (406 aa)
	LRP1	LDL receptor related protein 1. (4544 aa)
	ABCA8	ATP binding cassette subfamily A member 8. (1621 aa)
	ABCA7	ATP binding cassette subfamily A member 7. (2146 aa)
	RXRA	Retinoid X receptor alpha. (532 aa)
	NAXE	NAD(P)HX epimerase. (259 aa)
	ABCG4	ATP binding cassette subfamily G member 4. (646 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	ABCA12	ATP binding cassette subfamily A member 12. (2602 aa)
	TTC39A	Tetratricopeptide repeat domain 39A. (613 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	ABCA3	ENSANAP00000031638	ENSANAP00000036775	ATP binding cassette subfamily A member 1.	ATP binding cassette subfamily A member 3.	0.455
ABCA1	APOE	ENSANAP00000031638	ENSANAP00000021488	ATP binding cassette subfamily A member 1.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.764
ABCA1	CETP	ENSANAP00000031638	ENSANAP00000011865	ATP binding cassette subfamily A member 1.	Cholesteryl ester transfer protein.	0.657
ABCA1	NR1H2	ENSANAP00000031638	ENSANAP00000034385	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 2.	0.849
ABCA1	NR1H3	ENSANAP00000031638	ENSANAP00000041401	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 3.	0.790
ABCA1	PLTP	ENSANAP00000031638	ENSANAP00000021392	ATP binding cassette subfamily A member 1.	Phospholipid transfer protein.	0.581
ABCA1	RXRA	ENSANAP00000031638	ENSANAP00000009132	ATP binding cassette subfamily A member 1.	Retinoid X receptor alpha.	0.665
ABCA1	SREBF2	ENSANAP00000031638	ENSANAP00000019976	ATP binding cassette subfamily A member 1.	Sterol regulatory element binding transcription factor 2.	0.572
ABCA12	NR1H2	ENSANAP00000035585	ENSANAP00000034385	ATP binding cassette subfamily A member 12.	Nuclear receptor subfamily 1 group H member 2.	0.424
ABCA2	ABCA3	ENSANAP00000021360	ENSANAP00000036775	ATP binding cassette subfamily A member 2.	ATP binding cassette subfamily A member 3.	0.490
ABCA2	APOE	ENSANAP00000021360	ENSANAP00000021488	ATP binding cassette subfamily A member 2.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.422
ABCA2	NR1H2	ENSANAP00000021360	ENSANAP00000034385	ATP binding cassette subfamily A member 2.	Nuclear receptor subfamily 1 group H member 2.	0.667
ABCA2	NR1H3	ENSANAP00000021360	ENSANAP00000041401	ATP binding cassette subfamily A member 2.	Nuclear receptor subfamily 1 group H member 3.	0.667
ABCA2	RXRA	ENSANAP00000021360	ENSANAP00000009132	ATP binding cassette subfamily A member 2.	Retinoid X receptor alpha.	0.555
ABCA3	ABCA1	ENSANAP00000036775	ENSANAP00000031638	ATP binding cassette subfamily A member 3.	ATP binding cassette subfamily A member 1.	0.455
ABCA3	ABCA2	ENSANAP00000036775	ENSANAP00000021360	ATP binding cassette subfamily A member 3.	ATP binding cassette subfamily A member 2.	0.490
ABCA5	NR1H2	ENSANAP00000023662	ENSANAP00000034385	ATP binding cassette subfamily A member 5.	Nuclear receptor subfamily 1 group H member 2.	0.403
ABCA5	NR1H3	ENSANAP00000023662	ENSANAP00000041401	ATP binding cassette subfamily A member 5.	Nuclear receptor subfamily 1 group H member 3.	0.403
ABCA7	APOE	ENSANAP00000006596	ENSANAP00000021488	ATP binding cassette subfamily A member 7.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.493
ABCA7	TREM2	ENSANAP00000006596	ENSANAP00000036261	ATP binding cassette subfamily A member 7.	Triggering receptor expressed on myeloid cells 2.	0.572