STRINGSTRING
NFKB1 NFKB1 SCAP SCAP GFI1 GFI1 SNAI2 SNAI2 INSIG2 INSIG2 ERLIN1 ERLIN1 ERLIN2 ERLIN2 BMP5 BMP5 INSIG1 INSIG1 MALRD1 MALRD1 FGF19 FGF19 APOE APOE PROX1 PROX1 SNAI1 SNAI1 CYP27B1 CYP27B1 NR0B1 NR0B1 SOD1 SOD1 REST REST DKKL1 DKKL1 ENSANAP00000037159 ENSANAP00000037159 DKK3 DKK3 BMP2 BMP2 WNT4 WNT4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
SCAPUncharacterized protein. (1241 aa)
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (233 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
ERLIN2ER lipid raft associated 2. (369 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (280 aa)
MALRD1MAM and LDL receptor class A domain containing 1. (1851 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (281 aa)
PROX1Prospero homeobox 1. (737 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (152 aa)
RESTRE1 silencing transcription factor. (1109 aa)
DKKL1Dickkopf like acrosomal protein 1. (241 aa)
ENSANAP00000037159WD_REPEATS_REGION domain-containing protein. (508 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (350 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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