STRINGSTRING
SLC25A5 SLC25A5 VDAC1 VDAC1 ATP6V1B2 ATP6V1B2 FYCO1 FYCO1 SPTLC2 SPTLC2 KDR KDR NOD1 NOD1 CLN3 CLN3 SCOC SCOC HMOX1 HMOX1 ENSANAP00000029029 ENSANAP00000029029 SESN3 SESN3 IKBKG IKBKG RNF31 RNF31 TMEM39A TMEM39A EPM2A EPM2A UBQLN4 UBQLN4 EXOC7 EXOC7 PINK1 PINK1 WDR24 WDR24 UBQLN2 UBQLN2 HTT HTT ENSANAP00000026489 ENSANAP00000026489 PIP4K2A PIP4K2A ULK1 ULK1 RIPK2 RIPK2 BAG3 BAG3 SMCR8 SMCR8 MTMR8 MTMR8 ATP6V0C ATP6V0C LOC105733430 LOC105733430 MTOR MTOR USP36 USP36 LARP1 LARP1 SESN2 SESN2 ENSANAP00000024200 ENSANAP00000024200 IRGM IRGM SNX7 SNX7 CDK5 CDK5 VPS13C VPS13C POLDIP2 POLDIP2 LOC105727017 LOC105727017 TBK1 TBK1 HSPB8 HSPB8 SLC25A4 SLC25A4 VPS13D VPS13D KIAA1324 KIAA1324 AKT1 AKT1 PIK3CA PIK3CA RUBCN RUBCN ATP6V1C2 ATP6V1C2 WAC WAC PIK3R4 PIK3R4 ENSANAP00000017672 ENSANAP00000017672 DCN-2 DCN-2 ENSANAP00000016051 ENSANAP00000016051 SCFD1 SCFD1 ATP6V0A1 ATP6V0A1 SNX18 SNX18 SNX30 SNX30 PRKAA2 PRKAA2 MAPK3 MAPK3 AMBRA1 AMBRA1 ATP6V0B ATP6V0B ENSANAP00000040170 ENSANAP00000040170 UVRAG UVRAG STING1 STING1 LZTS1 LZTS1 NRBP2 NRBP2 RAB3GAP2 RAB3GAP2 ATG2A ATG2A NUPR1 NUPR1 LRRK2 LRRK2 ENSANAP00000038942 ENSANAP00000038942 TRIM13 TRIM13 ENSANAP00000038876 ENSANAP00000038876 WDR45 WDR45 SMG1 SMG1 CLEC16A CLEC16A SIRT1 SIRT1 SNX5 SNX5 LOC105717376 LOC105717376 PIK3C3 PIK3C3 GPSM1 GPSM1 LRSAM1 LRSAM1 PIP4K2C PIP4K2C VPS35 VPS35 TECPR1 TECPR1 ATP6V0A2 ATP6V0A2 RNF41 RNF41 SPTLC1 SPTLC1 EXOC4 EXOC4 SUPT5H SUPT5H BNIP3L BNIP3L LOC105727016 LOC105727016 FEZ1 FEZ1 TBC1D25 TBC1D25 PIP4K2B PIP4K2B ATG14 ATG14 NPC1 NPC1 TSC2 TSC2 PAFAH1B2 PAFAH1B2 TIGAR TIGAR ENSANAP00000000156 ENSANAP00000000156 NEDD4 NEDD4 ENSANAP00000000365 ENSANAP00000000365 EXOC8 EXOC8 CDK5R1 CDK5R1 ATP6V1H ATP6V1H HIF1A HIF1A SLC25A6 SLC25A6 WIPI1 WIPI1 LOC105714732 LOC105714732 TSC1 TSC1 ENSANAP00000002889 ENSANAP00000002889 ERN1 ERN1 FEZ2 FEZ2 ENSANAP00000003946 ENSANAP00000003946 LOC105717178 LOC105717178 MAPK10 MAPK10 MAPK8 MAPK8 EXOC1 EXOC1 CALCOCO2 CALCOCO2 USP30 USP30 LACRT LACRT BNIP3 BNIP3 ENSANAP00000006275 ENSANAP00000006275 HDAC6 HDAC6 RAB3GAP1 RAB3GAP1 SNX4 SNX4 IL4 IL4 QSOX1 QSOX1 ATP13A2 ATP13A2 VPS26A VPS26A ENSANAP00000008855 ENSANAP00000008855 RHEB RHEB RUFY4 RUFY4 SEC22B SEC22B C9orf72 C9orf72 ATG5 ATG5 DCN DCN CHMP4B CHMP4B TMEM39B TMEM39B EHMT2 EHMT2 ATP6V1G1 ATP6V1G1 CAPNS1 CAPNS1 ADRB2 ADRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
VDAC1Voltage dependent anion channel 1. (292 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (540 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1498 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (560 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
CLN3Battenin. (422 aa)
SCOCShort coiled-coil protein. (158 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ENSANAP00000029029Uncharacterized protein. (362 aa)
SESN3Sestrin 3. (492 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
RNF31Uncharacterized protein. (1072 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
EPM2AEPM2A glucan phosphatase, laforin. (330 aa)
UBQLN4Ubiquilin 4. (601 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (720 aa)
PINK1PTEN induced kinase 1. (525 aa)
WDR24WD repeat domain 24. (914 aa)
UBQLN2Ubiquilin 2. (624 aa)
HTTHuntingtin. (3132 aa)
ENSANAP00000026489Uncharacterized protein. (270 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (380 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1040 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
BAG3BCL2 associated athanogene 3. (575 aa)
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)
MTMR8Myotubularin related protein 8. (716 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
LOC105733430V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (376 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1126 aa)
LARP1La ribonucleoprotein domain family member 1. (1021 aa)
SESN2Sestrin 2. (480 aa)
ENSANAP00000024200Protein kinase domain-containing protein. (279 aa)
IRGMImmunity related GTPase M. (188 aa)
SNX7Sorting nexin 7. (451 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (314 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3721 aa)
POLDIP2ApaG domain-containing protein. (368 aa)
LOC105727017ADP/ATP translocase 3-like. (290 aa)
TBK1TANK binding kinase 1. (690 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (295 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4386 aa)
KIAA1324KIAA1324. (1016 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RUBCNRubicon autophagy regulator. (1004 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (429 aa)
WACWW domain containing adaptor with coiled-coil. (652 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1271 aa)
ENSANAP00000017672PX domain-containing protein. (378 aa)
DCN-2Decorin; May affect the rate of fibrils formation. (97 aa)
ENSANAP00000016051Uncharacterized protein. (205 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (641 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (837 aa)
SNX18Sorting nexin. (624 aa)
SNX30Sorting nexin family member 30. (404 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1289 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (252 aa)
ENSANAP00000040170V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (116 aa)
UVRAGUV radiation resistance associated. (699 aa)
STING1Transmembrane protein 173. (327 aa)
LZTS1Leucine zipper tumor suppressor 1. (595 aa)
NRBP2Nuclear receptor binding protein 2. (499 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1328 aa)
ATG2AAutophagy related 2A. (1966 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
LRRK2Leucine rich repeat kinase 2. (2515 aa)
ENSANAP00000038942Uncharacterized protein. (48 aa)
TRIM13Tripartite motif containing 13. (460 aa)
ENSANAP00000038876Uncharacterized protein. (266 aa)
WDR45Uncharacterized protein. (360 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3664 aa)
CLEC16AC-type lectin domain containing 16A. (1053 aa)
SIRT1Sirtuin 1. (751 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
LOC105717376Uncharacterized protein. (273 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (892 aa)
GPSM1G protein signaling modulator 1. (694 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (722 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (803 aa)
TECPR1Tectonin beta-propeller repeat containing 1. (1234 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (802 aa)
RNF41Ring finger protein 41. (317 aa)
SPTLC1Aminotran_1_2 domain-containing protein. (488 aa)
EXOC4Exocyst complex component 4. (974 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
BNIP3LBCL2 interacting protein 3 like. (212 aa)
LOC105727016Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (290 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
TBC1D25TBC1 domain family member 25. (687 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
ATG14Autophagy related 14. (492 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
TSC2TSC complex subunit 2. (1807 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
ENSANAP00000000156Uncharacterized protein. (254 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1292 aa)
ENSANAP00000000365ApaG domain-containing protein. (346 aa)
EXOC8Exocyst complex component 8. (725 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (475 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
SLC25A6Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (275 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (434 aa)
LOC105714732V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (112 aa)
TSC1TSC complex subunit 1. (1163 aa)
ENSANAP00000002889Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (746 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (1012 aa)
FEZ2Fasciculation and elongation protein zeta 2. (382 aa)
ENSANAP00000003946Uncharacterized protein. (118 aa)
LOC105717178V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
MAPK10Mitogen-activated protein kinase. (533 aa)
MAPK8Mitogen-activated protein kinase. (387 aa)
EXOC1Exocyst complex component 1. (901 aa)
CALCOCO2Uncharacterized protein. (470 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (534 aa)
LACRTLacritin. (137 aa)
BNIP3BCL2 interacting protein 3. (236 aa)
ENSANAP00000006275Uncharacterized protein. (133 aa)
HDAC6Histone deacetylase 6. (1226 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
SNX4Sorting nexin 4. (435 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (152 aa)
QSOX1Sulfhydryl oxidase. (744 aa)
ATP13A2ATPase cation transporting 13A2. (1094 aa)
VPS26AVPS26, retromer complex component A. (327 aa)
ENSANAP00000008855Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (175 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
RUFY4RUN and FYVE domain containing 4. (600 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
DCNDecorin; May affect the rate of fibrils formation. (361 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
TMEM39BTransmembrane protein 39B. (505 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1245 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
CAPNS1Uncharacterized protein. (316 aa)
ADRB2Adrenoceptor beta 2. (426 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (18%) [HD]