STRINGSTRING
HMOX1 HMOX1 TMEM39A TMEM39A UBQLN4 UBQLN4 PINK1 PINK1 MTOR MTOR SMCR8 SMCR8 USP36 USP36 POLDIP2 POLDIP2 AKT1 AKT1 PIK3CA PIK3CA RUBCN RUBCN SCFD1 SCFD1 EHMT2 EHMT2 FEZ1 FEZ1 NPC1 NPC1 TSC2 TSC2 TIGAR TIGAR TMEM39B TMEM39B CHMP4B CHMP4B SEC22B SEC22B QSOX1 QSOX1 USP30 USP30 FEZ2 FEZ2 TSC1 TSC1 ENSANAP00000000365 ENSANAP00000000365 LZTS1 LZTS1 NRBP2 NRBP2 NUPR1 NUPR1 LRRK2 LRRK2 SMG1 SMG1 CLEC16A CLEC16A RNF41 RNF41
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
UBQLN4Ubiquilin 4. (601 aa)
PINK1PTEN induced kinase 1. (525 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1126 aa)
POLDIP2ApaG domain-containing protein. (368 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RUBCNRubicon autophagy regulator. (1004 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (641 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1245 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
TSC2TSC complex subunit 2. (1807 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
TMEM39BTransmembrane protein 39B. (505 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
QSOX1Sulfhydryl oxidase. (744 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (534 aa)
FEZ2Fasciculation and elongation protein zeta 2. (382 aa)
TSC1TSC complex subunit 1. (1163 aa)
ENSANAP00000000365ApaG domain-containing protein. (346 aa)
LZTS1Leucine zipper tumor suppressor 1. (595 aa)
NRBP2Nuclear receptor binding protein 2. (499 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
LRRK2Leucine rich repeat kinase 2. (2515 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3664 aa)
CLEC16AC-type lectin domain containing 16A. (1053 aa)
RNF41Ring finger protein 41. (317 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.