STRINGSTRING
ARID1A ARID1A NDC80 NDC80 SMARCD1 SMARCD1 SMARCA2 SMARCA2 DUSP1 DUSP1 NUF2 NUF2 SMARCD2 SMARCD2 BCL7A BCL7A ENSANAP00000020964 ENSANAP00000020964 ANAPC15 ANAPC15 XRCC3 XRCC3 CDT1 CDT1 CCNB1 CCNB1 ZWINT ZWINT ANAPC4 ANAPC4 CDC16 CDC16 ENSANAP00000023031 ENSANAP00000023031 NEK6 NEK6 MAD2L2 MAD2L2 TRIP13 TRIP13 CENPE CENPE GEN1 GEN1 LOC105721409 LOC105721409 SMARCC1 SMARCC1 TEX14 TEX14 BUB1B BUB1B CDC6 CDC6 ENSANAP00000026808 ENSANAP00000026808 ENSANAP00000006462 ENSANAP00000006462 BUB1 BUB1 LOC105718674 LOC105718674 BCL7C BCL7C MAD2L1BP MAD2L1BP FBXO5 FBXO5 PRAP1 PRAP1 ENSANAP00000000987 ENSANAP00000000987 KLHL22 KLHL22 RIOK2 RIOK2 SPC25 SPC25 ENSANAP00000002519 ENSANAP00000002519 SMARCD3 SMARCD3 LCMT1 LCMT1 MAD1L1 MAD1L1 APC APC LOC105715186 LOC105715186 RB1 RB1 MAD2L1 MAD2L1 ARID1B ARID1B ENSANAP00000027633 ENSANAP00000027633 ENSANAP00000027891 ENSANAP00000027891 SMARCB1 SMARCB1 ACTL6B ACTL6B SMARCE1 SMARCE1 RAD21 RAD21 USP44 USP44 CDC26 CDC26 HECW2 HECW2 ZW10 ZW10 SPDL1 SPDL1 BIRC5 BIRC5 SMARCC2 SMARCC2 PBRM1 PBRM1 INCENP INCENP NSMCE2 NSMCE2 DPF2 DPF2 CDC20 CDC20 CDC27 CDC27 PHF10 PHF10 ZWILCH ZWILCH SPC24 SPC24 ANAPC7 ANAPC7 BCL7B BCL7B IK IK SMARCA4 SMARCA4 LOC105711628 LOC105711628 DYNC1LI1 DYNC1LI1 KNTC1 KNTC1 PSMG2 PSMG2 CUL3 CUL3 AURKB AURKB DLGAP5 DLGAP5 ARID2 ARID2 ESPL1 ESPL1 ATM ATM DPF1 DPF1 CENPF CENPF PCID2 PCID2 DPF3 DPF3 TPR TPR ENSANAP00000014459 ENSANAP00000014459 ENSANAP00000014488 ENSANAP00000014488 ENSANAP00000015418 ENSANAP00000015418 PLK1 PLK1 CDC23 CDC23 ENSANAP00000016389 ENSANAP00000016389 ANAPC11 ANAPC11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARID1AAT-rich interaction domain 1A. (2018 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
SMARCD1SWIB domain-containing protein. (515 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1587 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (210 aa)
ENSANAP00000020964Uncharacterized protein. (72 aa)
ANAPC15Anaphase promoting complex subunit 15. (161 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (398 aa)
CDT1CDT1 domain-containing protein. (547 aa)
CCNB1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (429 aa)
ZWINTZW10 interacting kinetochore protein. (289 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
CDC16Cell division cycle 16. (453 aa)
ENSANAP00000023031Uncharacterized protein. (999 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (326 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (224 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (409 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2668 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (909 aa)
LOC105721409HMG box domain-containing protein. (390 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1106 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1366 aa)
BUB1BBUB1 N-terminal domain-containing protein. (999 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa)
ENSANAP00000026808HMG box domain-containing protein. (397 aa)
ENSANAP00000006462RING-type domain-containing protein. (77 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1017 aa)
LOC105718674Uncharacterized protein. (43 aa)
BCL7CBAF chromatin remodeling complex subunit BCL7C. (242 aa)
MAD2L1BPMAD2L1 binding protein. (299 aa)
FBXO5F-box protein 5. (422 aa)
PRAP1Uncharacterized protein. (154 aa)
ENSANAP00000000987HMG box domain-containing protein. (391 aa)
KLHL22Kelch like family member 22. (634 aa)
RIOK2RIO kinase 2. (552 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (225 aa)
ENSANAP00000002519Uncharacterized protein. (131 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
LCMT1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (343 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (699 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
LOC105715186HMG box domain-containing protein. (371 aa)
RB1RB transcriptional corepressor 1. (925 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
ARID1BAT-rich interaction domain 1B. (1539 aa)
ENSANAP00000027633SWIB domain-containing protein. (547 aa)
ENSANAP00000027891Uncharacterized protein. (161 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (394 aa)
ACTL6BActin like 6B; Belongs to the actin family. (443 aa)
SMARCE1HMG box domain-containing protein. (414 aa)
RAD21RAD21 cohesin complex component. (631 aa)
USP44Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (712 aa)
CDC26Cell division cycle 26. (85 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
ZW10Zw10 kinetochore protein. (779 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
BIRC5Baculoviral IAP repeat containing 5. (118 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1240 aa)
PBRM1Polybromo 1. (1725 aa)
INCENPInner centromere protein. (911 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (246 aa)
DPF2Double PHD fingers 2. (405 aa)
CDC20Cell division cycle 20. (519 aa)
CDC27Cell division cycle 27. (831 aa)
PHF10PHD finger protein 10. (499 aa)
ZWILCHZwilch kinetochore protein. (589 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (197 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
BCL7BBAF chromatin remodeling complex subunit BCL7B. (202 aa)
IKIK cytokine. (557 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1728 aa)
LOC105711628CULLIN_2 domain-containing protein; Belongs to the cullin family. (596 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
KNTC1Kinetochore associated 1. (2212 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (264 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
DLGAP5DLG associated protein 5. (856 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2051 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
DPF1Double PHD fingers 1. (424 aa)
CENPFCentromere protein F. (3116 aa)
PCID2PCI domain containing 2. (401 aa)
DPF3Double PHD fingers 3. (412 aa)
TPRTranslocated promoter region, nuclear basket protein. (2369 aa)
ENSANAP00000014459HMG box domain-containing protein. (164 aa)
ENSANAP00000014488Uncharacterized protein. (71 aa)
ENSANAP00000015418CDT1 domain-containing protein. (517 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
CDC23Cell division cycle 23. (597 aa)
ENSANAP00000016389Uncharacterized protein; Belongs to the cyclin family. (363 aa)
ANAPC11Anaphase promoting complex subunit 11. (164 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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