STRINGSTRING
CSF1 CSF1 DHRS3 DHRS3 ATP2B1 ATP2B1 PTPN11 PTPN11 SMAD7 SMAD7 VDR VDR KL KL ATRAID ATRAID ENSANAP00000022622 ENSANAP00000022622 TGFB3 TGFB3 CYP27B1 CYP27B1 BMPR2 BMPR2 LTBP3 LTBP3 ZBTB16 ZBTB16 ALOX5 ALOX5 SLC8A1 SLC8A1 INTU INTU WNT5A WNT5A ACVR2A ACVR2A EGR2 EGR2 FGF23 FGF23 ENSANAP00000026192 ENSANAP00000026192 MDK MDK PTN PTN SGMS2 SGMS2 ECM1 ECM1 ISG15 ISG15 WNT10B WNT10B GATA1 GATA1 KREMEN2 KREMEN2 BMP2K BMP2K ENSANAP00000029453 ENSANAP00000029453 TGFB2 TGFB2 SRGN SRGN PHOSPHO1 PHOSPHO1 ACTN3 ACTN3 BCL2 BCL2 WNT4 WNT4 ESRRA ESRRA PTK2B PTK2B OSR2 OSR2 RUNX2 RUNX2 ACVR2B ACVR2B BMP6 BMP6 LTF LTF BMP2 BMP2 IFITM5 IFITM5 BGLAP BGLAP OSR1 OSR1 OMD OMD TGFB1 TGFB1 BMP4 BMP4 AHSG AHSG KREMEN1 KREMEN1 RXRB RXRB BMP7 BMP7 TACR1 TACR1 ANO6 ANO6 ACVR1 ACVR1 MEF2C MEF2C RFLNA RFLNA PKDCC PKDCC SIX2 SIX2 NELL1 NELL1 SCUBE2 SCUBE2 ADRB2 ADRB2 MAPK1 MAPK1 NOTCH1 NOTCH1 FBN2 FBN2 TENT5A TENT5A BMPR1B BMPR1B P2RX7 P2RX7 COMP COMP NIPBL NIPBL SOX9 SOX9 BMPR1A BMPR1A PTGER4 PTGER4 MAPK3 MAPK3 OXT OXT SOST SOST MAPK14 MAPK14 CHSY1 CHSY1 LRP4 LRP4 GFRA4 GFRA4 ZMPSTE24 ZMPSTE24 GDF10 GDF10 DDR2 DDR2 RXRA RXRA ENPP1 ENPP1 SFRP1 SFRP1 NOTUM NOTUM TXLNG TXLNG RFLNB RFLNB TFAP2A TFAP2A CCN1 CCN1 DKK1 DKK1 SMAD6 SMAD6 FZD9 FZD9 CALCR CALCR BCOR BCOR FAM20C FAM20C SOX11 SOX11 ANKH ANKH S1PR1 S1PR1 TPH1 TPH1 HIF1A HIF1A ADGRV1 ADGRV1 GPM6B GPM6B MATN1 MATN1 SMAD3 SMAD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF1Colony stimulating factor 1. (619 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
SMAD7Mothers against decapentaplegic homolog. (489 aa)
VDRVitamin D receptor. (400 aa)
KLKlotho. (998 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
ENSANAP00000022622PTN_MK_N domain-containing protein. (72 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1265 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
ALOX5Arachidonate 5-lipoxygenase. (699 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
INTUInturned planar cell polarity protein. (932 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
EGR2Early growth response 2. (473 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
ENSANAP00000026192Uncharacterized protein. (31 aa)
MDKUncharacterized protein. (144 aa)
PTNPleiotrophin. (168 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
ECM1Extracellular matrix protein 1. (557 aa)
ISG15ISG15 ubiquitin like modifier. (166 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
GATA1GATA binding protein 1. (413 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)
BMP2KBMP2 inducible kinase. (1132 aa)
ENSANAP00000029453Uncharacterized protein. (284 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SRGNSerglycin. (158 aa)
PHOSPHO1Uncharacterized protein. (267 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (943 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ESRRAEstrogen related receptor alpha. (435 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
OSR2Odd-skipped related transciption factor 2. (415 aa)
RUNX2RUNX family transcription factor 2. (587 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
BMP6Bone morphogenetic protein 6. (508 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (100 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
OMDOsteomodulin. (432 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (378 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
AHSGAlpha 2-HS glycoprotein. (357 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (460 aa)
RXRBRetinoid X receptor beta. (533 aa)
BMP7Bone morphogenetic protein 7. (410 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ANO6Anoctamin. (929 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
MEF2CMyocyte enhancer factor 2C. (490 aa)
RFLNARefilin A. (216 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (479 aa)
SIX2SIX homeobox 2. (293 aa)
NELL1Neural EGFL like 1. (810 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1017 aa)
ADRB2Adrenoceptor beta 2. (426 aa)
MAPK1Mitogen-activated protein kinase. (376 aa)
NOTCH1Notch receptor 1. (2527 aa)
FBN2Fibrillin 2. (2912 aa)
TENT5ATerminal nucleotidyltransferase 5A. (508 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
NIPBLNipped-B protein. (2804 aa)
SOX9SRY-box transcription factor 9. (505 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
OXTOxytocin/neurophysin I prepropeptide. (125 aa)
SOSTSclerostin. (213 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CHSY1Hexosyltransferase. (807 aa)
LRP4LDL receptor related protein 4. (1948 aa)
GFRA4GDNF family receptor alpha 4. (295 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (879 aa)
RXRARetinoid X receptor alpha. (532 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (898 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (496 aa)
TXLNGTaxilin gamma. (524 aa)
RFLNBRefilin B. (144 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
CCN1Cellular communication network factor 1. (381 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
SMAD6Mothers against decapentaplegic homolog. (494 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (474 aa)
BCORBCL6 corepressor. (1761 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (565 aa)
SOX11Transcription factor SOX. (449 aa)
ANKHANKH inorganic pyrophosphate transport regulator. (492 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6245 aa)
GPM6BGlycoprotein M6B. (305 aa)
MATN1Matrilin 1. (496 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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