20 items (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYT7	Synaptotagmin 7. (686 aa)
	OSBPL2	Oxysterol-binding protein; Belongs to the OSBP family. (480 aa)
	RELCH	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
	SERAC1	Serine active site containing 1. (654 aa)
	PIP4K2A	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (380 aa)
	ARL8A	ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	LDLR	Low density lipoprotein receptor. (786 aa)
	STARD4	StAR related lipid transfer domain containing 4. (205 aa)
	VPS4A	Uncharacterized protein; Belongs to the AAA ATPase family. (492 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (308 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1277 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (603 aa)
	TSPO2	Translocator protein 2. (170 aa)
	TPCN2	Two pore segment channel 2. (752 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (203 aa)
	OSBP	Oxysterol-binding protein; Belongs to the OSBP family. (807 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2220 aa)
	ARL8B	ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (244 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	NPC1	ENSANAP00000031638	ENSANAP00000012524	ATP binding cassette subfamily A member 1.	NPC intracellular cholesterol transporter 1.	0.574
ABCG1	NPC1	ENSANAP00000015403	ENSANAP00000012524	ATP binding cassette subfamily G member 1.	NPC intracellular cholesterol transporter 1.	0.606
LDLR	LDLRAP1	ENSANAP00000037940	ENSANAP00000011745	Low density lipoprotein receptor.	Low density lipoprotein receptor adaptor protein 1.	0.984
LDLRAP1	LDLR	ENSANAP00000011745	ENSANAP00000037940	Low density lipoprotein receptor adaptor protein 1.	Low density lipoprotein receptor.	0.984
NPC1	ABCA1	ENSANAP00000012524	ENSANAP00000031638	NPC intracellular cholesterol transporter 1.	ATP binding cassette subfamily A member 1.	0.574
NPC1	ABCG1	ENSANAP00000012524	ENSANAP00000015403	NPC intracellular cholesterol transporter 1.	ATP binding cassette subfamily G member 1.	0.606
NPC1	NPC2	ENSANAP00000012524	ENSANAP00000034877	NPC intracellular cholesterol transporter 1.	NPC intracellular cholesterol transporter 2.	0.994
NPC2	NPC1	ENSANAP00000034877	ENSANAP00000012524	NPC intracellular cholesterol transporter 2.	NPC intracellular cholesterol transporter 1.	0.994
PIP4K2A	SYT7	ENSANAP00000026285	ENSANAP00000004146	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.	Synaptotagmin 7.	0.566
STAR	STARD4	ENSANAP00000042210	ENSANAP00000001823	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	StAR related lipid transfer domain containing 4.	0.644
STAR	TSPO2	ENSANAP00000042210	ENSANAP00000018704	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	Translocator protein 2.	0.759
STARD4	STAR	ENSANAP00000001823	ENSANAP00000042210	StAR related lipid transfer domain containing 4.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.644
SYT7	PIP4K2A	ENSANAP00000004146	ENSANAP00000026285	Synaptotagmin 7.	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.	0.566
TSPO2	STAR	ENSANAP00000018704	ENSANAP00000042210	Translocator protein 2.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	0.759