STRINGSTRING
EIF2A EIF2A ENSANAP00000037159 ENSANAP00000037159 SREBF2 SREBF2 ENSANAP00000018891 ENSANAP00000018891 INSIG1 INSIG1 ERLIN2 ERLIN2 ERLIN1 ERLIN1 SREBF1 SREBF1 INSIG2 INSIG2 SCAP SCAP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (586 aa)
ENSANAP00000037159WD_REPEATS_REGION domain-containing protein. (508 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1143 aa)
ENSANAP00000018891Uncharacterized protein. (102 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (280 aa)
ERLIN2ER lipid raft associated 2. (369 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1179 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (233 aa)
SCAPUncharacterized protein. (1241 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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