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LOC105705093 LOC105705093 TECR TECR PDHA1 PDHA1 TPST1 TPST1 OXSM OXSM ACOT8 ACOT8 ACSM5 ACSM5 ELOVL6 ELOVL6 ACSM6 ACSM6 ACOT12 ACOT12 PPCDC PPCDC ENSANAP00000030707 ENSANAP00000030707 MLYCD MLYCD DGAT2 DGAT2 GPAM GPAM ENSANAP00000031573 ENSANAP00000031573 PMVK PMVK PANK4 PANK4 DLAT DLAT HSD17B4 HSD17B4 LOC110568288 LOC110568288 ENSANAP00000014530 ENSANAP00000014530 ENSANAP00000014264 ENSANAP00000014264 SULT2B1 SULT2B1 FITM2 FITM2 SULT1B1 SULT1B1 SLC26A2 SLC26A2 DGAT1 DGAT1 PANK3 PANK3 TDO2 TDO2 ACSM2B ACSM2B DCAKD DCAKD BPNT1 BPNT1 FAR2 FAR2 LOC105725511 LOC105725511 ENPP1 ENPP1 ACSBG2 ACSBG2 PPT2 PPT2 ACSF3 ACSF3 LOC105725504 LOC105725504 HMGCS1 HMGCS1 MVD MVD ACSS1 ACSS1 NUDT19 NUDT19 ABCD1 ABCD1 LOC105708316 LOC105708316 PANK2 PANK2 PAPSS2 PAPSS2 ACACB ACACB DLST DLST ACACA ACACA ACLY ACLY ACOT7 ACOT7 ELOVL7 ELOVL7 ACSL4 ACSL4 ELOVL3 ELOVL3 AASS AASS ACOT9 ACOT9 LOC105725420 LOC105725420 CCDC30 CCDC30 ACSS2 ACSS2 DIP2A DIP2A LOC105725505 LOC105725505 ELOVL4 ELOVL4 NUDT7 NUDT7 GLYAT GLYAT ACOT4 ACOT4 SULT1C4 SULT1C4 ACOT11 ACOT11 SLC25A16 SLC25A16 SUCLG1 SUCLG1 OGDH OGDH PDHB PDHB LOC105723049 LOC105723049 ACSL6 ACSL6 LOC105724312 LOC105724312 AADAT AADAT THEM5 THEM5 PDHX PDHX ACOT6 ACOT6 SULT1E1 SULT1E1 SULT2A1 SULT2A1 ACSL5 ACSL5 SULT1C3 SULT1C3 SUCLG2 SUCLG2 PIPOX PIPOX NUDT8 NUDT8 ELOVL5 ELOVL5 PANK1 PANK1 SLC25A1 SLC25A1 CROT CROT MPC2 MPC2 MCCC2 MCCC2 SLC26A1 SLC26A1 HDDC3 HDDC3 HMGCS2 HMGCS2 ACAT1 ACAT1 COASY COASY ELOVL2 ELOVL2 MVK MVK ENSANAP00000024505 ENSANAP00000024505 BAAT BAAT HMGCR HMGCR PAPSS1 PAPSS1 ACSL1 ACSL1 MCEE MCEE
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC105705093DFP domain-containing protein. (213 aa)
TECRTrans-2,3-enoyl-CoA reductase. (308 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (433 aa)
TPST1Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (370 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa)
ACOT8Acyl-CoA thioesterase 8. (320 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (579 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
ACSM6Acyl-CoA synthetase medium chain family member 6. (480 aa)
ACOT12Acyl-CoA thioesterase 12. (554 aa)
PPCDCPhosphopantothenoylcysteine decarboxylase. (221 aa)
ENSANAP00000030707Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (345 aa)
MLYCDMalonyl-CoA decarboxylase. (493 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (388 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
ENSANAP00000031573Uncharacterized protein. (91 aa)
PMVKPhosphomevalonate kinase. (192 aa)
PANK44'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. (773 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (761 aa)
LOC110568288MaoC-like domain-containing protein. (158 aa)
ENSANAP00000014530Uncharacterized protein. (383 aa)
ENSANAP00000014264Uncharacterized protein. (362 aa)
SULT2B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (331 aa)
FITM2Fat storage inducing transmembrane protein 2. (262 aa)
SULT1B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (283 aa)
SLC26A2Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (739 aa)
DGAT1O-acyltransferase. (491 aa)
PANK3Pantothenate kinase 3. (370 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
ACSM2BUncharacterized protein. (576 aa)
DCAKDDephospho-CoA kinase domain containing. (231 aa)
BPNT13'(2'), 5'-bisphosphate nucleotidase 1. (308 aa)
FAR2Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
LOC105725511Sulfotransferase; Belongs to the sulfotransferase 1 family. (294 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (898 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (477 aa)
PPT2Palmitoyl-protein thioesterase 2. (308 aa)
ACSF3Acyl-CoA synthetase family member 3. (577 aa)
LOC105725504Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
MVDDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (433 aa)
ACSS1Acetyl-coenzyme A synthetase. (688 aa)
NUDT19Nudix hydrolase 19. (376 aa)
ABCD1ATP binding cassette subfamily D member 1. (675 aa)
LOC105708316AMP-binding domain-containing protein. (656 aa)
PANK2Pantothenate kinase 2. (547 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (645 aa)
ACACBAcetyl-CoA carboxylase beta. (2435 aa)
DLSTDihydrolipoamide S-succinyltransferase. (456 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1123 aa)
ACOT7Uncharacterized protein. (381 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (670 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
AASSAminoadipate-semialdehyde synthase. (896 aa)
ACOT9Acyl-CoA thioesterase 9. (434 aa)
LOC105725420Sulfotransferase; Belongs to the sulfotransferase 1 family. (245 aa)
CCDC30Coiled-coil domain containing 30. (808 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (714 aa)
DIP2ADisco interacting protein 2 homolog A. (1571 aa)
LOC105725505Sulfotransferase; Belongs to the sulfotransferase 1 family. (301 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
NUDT7Nudix hydrolase 7. (232 aa)
GLYATGlycine-N-acyltransferase. (296 aa)
ACOT4Acyl-CoA thioesterase 4. (421 aa)
SULT1C4Sulfotransferase; Belongs to the sulfotransferase 1 family. (302 aa)
ACOT11Acyl-CoA thioesterase 11. (536 aa)
SLC25A16Solute carrier family 25 member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family. (292 aa)
SUCLG1Succinate-CoA ligase alpha subunit. (203 aa)
OGDHOxoglutarate dehydrogenase. (1034 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
LOC105723049Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (457 aa)
ACSL6AMP-binding domain-containing protein. (722 aa)
LOC105724312MaoC-like domain-containing protein. (168 aa)
AADATAminoadipate aminotransferase. (429 aa)
THEM5Thioesterase superfamily member 5. (246 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (478 aa)
ACOT6Uncharacterized protein. (429 aa)
SULT1E1Sulfotransferase; Belongs to the sulfotransferase 1 family. (276 aa)
SULT2A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (242 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)
SULT1C3Sulfotransferase; Belongs to the sulfotransferase 1 family. (304 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (440 aa)
PIPOXPipecolic acid and sarcosine oxidase. (390 aa)
NUDT8Nudix hydrolase domain-containing protein. (230 aa)
ELOVL5Elongation of very long chain fatty acids protein. (325 aa)
PANK1Pantothenate kinase 1. (607 aa)
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
CROTCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (623 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2. (519 aa)
SLC26A1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (717 aa)
HDDC3HD domain containing 3. (179 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (511 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
COASYCoenzyme A synthase. (593 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (296 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
ENSANAP00000024505Uncharacterized protein. (319 aa)
BAATBile acid-CoA:amino acid N-acyltransferase. (418 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (920 aa)
PAPSS13'-phosphoadenosine 5'-phosphosulfate synthase 1. (562 aa)
ACSL1Uncharacterized protein. (698 aa)
MCEEMethylmalonyl-CoA epimerase. (176 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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