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PTPA PTPA TMEM262 TMEM262 CACNG6 CACNG6 CACNB1 CACNB1 CACNA1F CACNA1F CACNA1H CACNA1H LOC105729037 LOC105729037 CATSPER2 CATSPER2 MICU2 MICU2 CACNG7 CACNG7 CACNA2D4 CACNA2D4 ENSANAP00000010339 ENSANAP00000010339 RYR1 RYR1 CATSPER1 CATSPER1 MICU1 MICU1 CACNB3 CACNB3 CACNA1A CACNA1A MICU3 MICU3 TRPV5 TRPV5 PKD1 PKD1 TRPC4 TRPC4 HSPA2 HSPA2 CACNA1D CACNA1D TRPV6 TRPV6 CACNG8 CACNG8 CATSPER3 CATSPER3 MCUB MCUB CACNA1S CACNA1S TMEM249 TMEM249 STAC3 STAC3 FKBP1B FKBP1B CATSPERG CATSPERG CACNG2 CACNG2 PKD1L1 PKD1L1 ASPH ASPH CALM1 CALM1 RYR2 RYR2 CACNA1E CACNA1E EFCAB9 EFCAB9 PDE4D PDE4D CATSPERD CATSPERD CACNB2 CACNB2 CATSPERZ CATSPERZ CACHD1 CACHD1 ENSANAP00000032056 ENSANAP00000032056 TRPC5 TRPC5 MCU MCU PKD2L1 PKD2L1 CACNA2D2 CACNA2D2 AKAP6 AKAP6 CACNA1C CACNA1C CACNA1B CACNA1B CALM3 CALM3 PDE4B PDE4B CACNA2D1 CACNA2D1 CACNB4 CACNB4 ORAI1 ORAI1 CACNA1G CACNA1G CACNG1 CACNG1 CACNA2D3 CACNA2D3 CACNA1I CACNA1I CATSPER4 CATSPER4 ATP2A1 ATP2A1 CATSPERE CATSPERE CACNG4 CACNG4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (380 aa)
TMEM262Transmembrane protein 262. (116 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (659 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1974 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2359 aa)
LOC105729037Uncharacterized protein. (116 aa)
CATSPER2Ion_trans domain-containing protein. (534 aa)
MICU2Mitochondrial calcium uptake 2. (432 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (306 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1138 aa)
ENSANAP00000010339MCU domain-containing protein. (296 aa)
RYR1Ryanodine receptor 1. (4981 aa)
CATSPER1Cation channel sperm associated 1. (756 aa)
MICU1Mitochondrial calcium uptake 1. (482 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2344 aa)
MICU3Mitochondrial calcium uptake family member 3. (530 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4274 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (601 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (765 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (349 aa)
CATSPER3Cation channel sperm associated 3. (397 aa)
MCUBMCU domain-containing protein. (336 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1830 aa)
TMEM249Transmembrane protein 249. (234 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
CATSPERGCation channel sperm associated auxiliary subunit gamma. (1152 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
PKD1L1Polycystin 1 like 1, transient receptor potential channel interacting. (2637 aa)
ASPHAspartate beta-hydroxylase. (764 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
RYR2Ryanodine receptor 2. (4650 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2296 aa)
EFCAB9EF-hand calcium binding domain 9. (197 aa)
PDE4DPhosphodiesterase. (748 aa)
CATSPERDCation channel sperm associated auxiliary subunit delta. (569 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (663 aa)
CATSPERZCatsper channel auxiliary subunit zeta. (218 aa)
CACHD1Cache domain containing 1. (1223 aa)
ENSANAP00000032056Uncharacterized protein. (608 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
MCUMitochondrial calcium uniporter. (350 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (805 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1103 aa)
AKAP6A-kinase anchoring protein 6. (2320 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2078 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2293 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
PDE4BPhosphodiesterase. (736 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2382 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1105 aa)
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2162 aa)
CATSPER4Cation channel sperm associated 4. (469 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1002 aa)
CATSPERECatsper channel auxiliary subunit epsilon. (951 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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