STRINGSTRING
SOX10 SOX10 FGF10 FGF10 NRTN NRTN MAPK3 MAPK3 FOXC2 FOXC2 MEF2C MEF2C ACVR1 ACVR1 OLFM1 OLFM1 BMP7 BMP7 CITED2 CITED2 FOLR1 FOLR1 MSX1 MSX1 BMP4 BMP4 PHACTR4 PHACTR4 TGFB1 TGFB1 FAM172A FAM172A SEMA3C SEMA3C HMGA2 HMGA2 SEMA6B SEMA6B OSR1 OSR1 DDX17 DDX17 SEMA3F SEMA3F SEMA4F SEMA4F SEMA5B SEMA5B ZFP64 ZFP64 BMP2 BMP2 FBXL17 FBXL17 NRP1 NRP1 PITX2 PITX2 ERBB4 ERBB4 RDH10 RDH10 FAM83D FAM83D KLHL12 KLHL12 ROCK1 ROCK1 CTNNB1 CTNNB1 OTUD5 OTUD5 EOMES EOMES NRP2 NRP2 TGFBR3L TGFBR3L RADIL RADIL WNT4 WNT4 ANXA6 ANXA6 EFNB1 EFNB1 SEMA4A SEMA4A SEMA4B SEMA4B SOX8 SOX8 BCL2 BCL2 TGFB2 TGFB2 WNT16 WNT16 ENSANAP00000029410 ENSANAP00000029410 PEF1 PEF1 SEMA3A SEMA3A KBTBD8 KBTBD8 FGF8 FGF8 FGFR2 FGFR2 DACT3 DACT3 NRG1 NRG1 PHOX2B PHOX2B AKNA AKNA RANBP3L RANBP3L GSC GSC ALX1 ALX1 LEF1 LEF1 SEMA6C SEMA6C LOC105707120 LOC105707120 SEMA4G SEMA4G DLG5 DLG5 EDN1 EDN1 TBX3 TBX3 LAMA5 LAMA5 PPP3R1 PPP3R1 WNT5A WNT5A EDNRA EDNRA ADAM15 ADAM15 WWTR1 WWTR1 PDCD6 PDCD6 SEMA3B SEMA3B SEMA3E SEMA3E SEMA3D SEMA3D FOXF2 FOXF2 LOC105709173 LOC105709173 AMER1 AMER1 TBX20 TBX20 HGF HGF SNAI1 SNAI1 GBX2 GBX2 ROCK2 ROCK2 FGF19 FGF19 CUL7 CUL7 STAT1 STAT1 TAPT1 TAPT1 WNT2 WNT2 GDNF GDNF TCOF1 TCOF1 FN1 FN1 TRIM28 TRIM28 TASOR TASOR LOC105725023 LOC105725023 HNRNPAB HNRNPAB SEMA3G SEMA3G FOXC1 FOXC1 WNT10A WNT10A ENSANAP00000017386 ENSANAP00000017386 LOC105714713 LOC105714713 GSK3B GSK3B POLR1B POLR1B SIX2 SIX2 ENSANAP00000015492 ENSANAP00000015492 RPS7 RPS7 SMAD4 SMAD4 SEMA6A SEMA6A MAPK1 MAPK1 NOTCH1 NOTCH1 WNT8A WNT8A HAND2 HAND2 ENSANAP00000013065 ENSANAP00000013065 ENSANAP00000012847 ENSANAP00000012847 TBX1 TBX1 SEMA7A SEMA7A JAG1 JAG1 TGFBR1 TGFBR1 ENG ENG HEY2 HEY2 CYP26C1 CYP26C1 S100A4 S100A4 SOX9 SOX9 WNT11 WNT11 BMPR1A BMPR1A SEMA4D SEMA4D ENSANAP00000009176 ENSANAP00000009176 FRZB FRZB EFNA1 EFNA1 LOXL3 LOXL3 EXT1 EXT1 EPB41L5 EPB41L5 LOC105730226 LOC105730226 SFRP1 SFRP1 HAS2 HAS2 TCF21 TCF21 RFLNB RFLNB FGFR1 FGFR1 ALDH1A2 ALDH1A2 SEMA4C SEMA4C EDNRB EDNRB SEMA5A SEMA5A LOXL2 LOXL2 SNAI2 SNAI2 EDN3 EDN3 RTN4 RTN4 CDH2 CDH2 HTR2B HTR2B SMO SMO LOC105714784 LOC105714784 SPRY1 SPRY1 SOX11 SOX11 NOTCH4 NOTCH4 LOC105722139 LOC105722139 HEYL HEYL ISL1 ISL1 HIF1A HIF1A DDX5 DDX5 PAX2 PAX2 TGFBR3 TGFBR3 CORO1C CORO1C HEY1 HEY1 NOG NOG KITLG KITLG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX10SRY-box transcription factor 10. (466 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NRTNNeurturin. (197 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
FOXC2Forkhead box C2. (489 aa)
MEF2CMyocyte enhancer factor 2C. (490 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
OLFM1Olfactomedin 1. (636 aa)
BMP7Bone morphogenetic protein 7. (410 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (250 aa)
FOLR1Folate receptor alpha. (255 aa)
MSX1Msh homeobox 1. (303 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
PHACTR4Phosphatase and actin regulator. (671 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (378 aa)
FAM172AFamily with sequence similarity 172 member A. (379 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (748 aa)
HMGA2Uncharacterized protein. (118 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (581 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (674 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
SEMA5BSemaphorin 5B. (1077 aa)
ZFP64ZFP64 zinc finger protein. (669 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
FBXL17F-box and leucine rich repeat protein 17. (659 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
PITX2Homeobox protein. (325 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
FAM83DFamily with sequence similarity 83 member D. (587 aa)
KLHL12Kelch like family member 12. (564 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1373 aa)
CTNNB1Catenin beta 1. (781 aa)
OTUD5OTU deubiquitinase 5. (571 aa)
EOMESEomesodermin. (705 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (309 aa)
RADILRap associating with DIL domain. (1072 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ANXA6Annexin. (673 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (761 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (835 aa)
SOX8SRY-box transcription factor 8. (446 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ENSANAP00000029410Protein kinase domain-containing protein. (959 aa)
PEF1Uncharacterized protein. (284 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (766 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (601 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (606 aa)
NRG1Neuregulin 1. (713 aa)
PHOX2BPaired like homeobox 2B. (301 aa)
AKNAAT-hook transcription factor. (1438 aa)
RANBP3LRAN binding protein 3 like. (487 aa)
GSCGoosecoid homeobox. (257 aa)
ALX1ALX homeobox 1. (326 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (960 aa)
LOC105707120Uncharacterized protein. (824 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1921 aa)
EDN1Endothelin 1. (212 aa)
TBX3T-box transcription factor 3. (743 aa)
LAMA5Laminin subunit alpha 5. (3587 aa)
PPP3R1Uncharacterized protein. (189 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADAM15ADAM metallopeptidase domain 15. (875 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
PDCD6Programmed cell death 6. (159 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (755 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (774 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
FOXF2Forkhead box F2. (415 aa)
LOC105709173Uncharacterized protein. (2229 aa)
AMER1APC membrane recruitment protein 1. (1008 aa)
TBX20T-box transcription factor 20. (447 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
CUL7Cullin 7; Belongs to the cullin family. (1728 aa)
STAT1Signal transducer and activator of transcription. (781 aa)
TAPT1Transmembrane anterior posterior transformation 1. (512 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1403 aa)
FN1Fibronectin 1. (2478 aa)
TRIM28Tripartite motif containing 28. (834 aa)
TASORTranscription activation suppressor. (1612 aa)
LOC105725023Uncharacterized protein. (336 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (332 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (813 aa)
FOXC1Forkhead box C1. (539 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
ENSANAP00000017386Uncharacterized protein. (274 aa)
LOC105714713LisH domain-containing protein. (674 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1163 aa)
SIX2SIX homeobox 2. (293 aa)
ENSANAP00000015492Uncharacterized protein. (175 aa)
RPS7Ribosomal protein S7. (194 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
MAPK1Mitogen-activated protein kinase. (376 aa)
NOTCH1Notch receptor 1. (2527 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
ENSANAP0000001306540S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (181 aa)
ENSANAP00000012847LisH domain-containing protein. (76 aa)
TBX1T-box transcription factor 1. (468 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (654 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
ENGEndoglin. (440 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
SOX9SRY-box transcription factor 9. (505 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
ENSANAP00000009176Reticulon. (340 aa)
FRZBFrizzled related protein. (325 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
LOC105730226Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
HAS2Hyaluronan synthase 2. (552 aa)
TCF21Transcription factor 21. (179 aa)
RFLNBRefilin B. (144 aa)
FGFR1Fibroblast growth factor receptor 1. (962 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (539 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (874 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
SEMA5ASemaphorin 5A. (1074 aa)
LOXL2Lysyl oxidase like 2. (869 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
EDN3Endothelin 3. (230 aa)
RTN4Reticulon. (1153 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
LOC10571478440S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
SOX11Transcription factor SOX. (449 aa)
NOTCH4Uncharacterized protein. (1707 aa)
LOC105722139Uncharacterized protein. (250 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
ISL1Uncharacterized protein. (349 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (661 aa)
PAX2Paired box 2. (416 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (532 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (376 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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