(37 nodes) Neural nucleus development network (Aotus nancymaae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	SEC16A	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2225 aa)
	ATF2	Activating transcription factor 2. (287 aa)
	TTBK1	Tau tubulin kinase 1. (1322 aa)
	LRRC1	Leucine rich repeat containing 1. (524 aa)
	LOC105732241	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (366 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (307 aa)
	CDK5R2	Cyclin-dependent kinase 5 activator. (367 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (230 aa)
	ENO3	Uncharacterized protein. (434 aa)
	LOC105707257	Phosphagen kinase C-terminal domain-containing protein; Belongs to the ATP:guanido phosphotransferase family. (190 aa)
	MAG	Myelin associated glycoprotein. (626 aa)
	SYPL2	Synaptophysin like 2. (266 aa)
	CCDC14	Coiled-coil domain containing 14. (912 aa)
	CHRNB2	Cholinergic receptor nicotinic beta 2 subunit. (504 aa)
	HOXB2	Homeobox B2. (356 aa)
	PHOX2A	Paired like homeobox 2A. (285 aa)
	FOXP2	Forkhead box P2. (741 aa)
	ENSANAP00000013693	Uncharacterized protein. (110 aa)
	YWHAE	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
	LOC105709097	Uncharacterized protein. (402 aa)
	PADI2	Peptidyl arginine deiminase 2. (635 aa)
	NKX2-1	NK2 homeobox 1. (402 aa)
	CKB	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (363 aa)
	KIRREL3	Kirre like nephrin family adhesion molecule 3. (779 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (561 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1283 aa)
	ARX	Aristaless related homeobox. (560 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
	LOC105734028	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
	SCRIB	Scribble planar cell polarity protein. (1647 aa)
	PHOX2B	Paired like homeobox 2B. (301 aa)
	G6PD	Glucose-6-phosphate dehydrogenase. (556 aa)
	HOXB1	Homeobox B1. (301 aa)
	BCL2	BCL2 apoptosis regulator. (240 aa)
	KCNC2	Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (618 aa)
	MAOB	Amine oxidase. (520 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A3	MAOB	ENSANAP00000025860	ENSANAP00000034624	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Amine oxidase.	0.404
ASCL1	PHOX2A	ENSANAP00000002350	ENSANAP00000011548	Achaete-scute family bHLH transcription factor 1.	Paired like homeobox 2A.	0.511
ASCL1	PHOX2B	ENSANAP00000002350	ENSANAP00000027405	Achaete-scute family bHLH transcription factor 1.	Paired like homeobox 2B.	0.496
ATF2	ENSANAP00000013693	ENSANAP00000039927	ENSANAP00000013693	Activating transcription factor 2.	Uncharacterized protein.	0.857
CDK5R1	CDK5R2	ENSANAP00000001453	ENSANAP00000001482	Cyclin-dependent kinase 5 activator.	Cyclin-dependent kinase 5 activator.	0.458
CDK5R2	CDK5R1	ENSANAP00000001482	ENSANAP00000001453	Cyclin-dependent kinase 5 activator.	Cyclin-dependent kinase 5 activator.	0.458
ENO3	G6PD	ENSANAP00000004594	ENSANAP00000028214	Uncharacterized protein.	Glucose-6-phosphate dehydrogenase.	0.798
ENSANAP00000013693	ATF2	ENSANAP00000013693	ENSANAP00000039927	Uncharacterized protein.	Activating transcription factor 2.	0.857
FOXP2	NKX2-1	ENSANAP00000012918	ENSANAP00000020931	Forkhead box P2.	NK2 homeobox 1.	0.405
G6PD	ENO3	ENSANAP00000028214	ENSANAP00000004594	Glucose-6-phosphate dehydrogenase.	Uncharacterized protein.	0.798
G6PD	LOC105709097	ENSANAP00000028214	ENSANAP00000018785	Glucose-6-phosphate dehydrogenase.	Uncharacterized protein.	0.672
LOC105709097	G6PD	ENSANAP00000018785	ENSANAP00000028214	Uncharacterized protein.	Glucose-6-phosphate dehydrogenase.	0.672
LOC105734028	YWHAE	ENSANAP00000027112	ENSANAP00000016902	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.	0.927
MAOB	ALDH1A3	ENSANAP00000034624	ENSANAP00000025860	Amine oxidase.	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	0.404
NKX2-1	FOXP2	ENSANAP00000020931	ENSANAP00000012918	NK2 homeobox 1.	Forkhead box P2.	0.405
PHOX2A	ASCL1	ENSANAP00000011548	ENSANAP00000002350	Paired like homeobox 2A.	Achaete-scute family bHLH transcription factor 1.	0.511
PHOX2B	ASCL1	ENSANAP00000027405	ENSANAP00000002350	Paired like homeobox 2B.	Achaete-scute family bHLH transcription factor 1.	0.496
SEC16A	SEC24B	ENSANAP00000033007	ENSANAP00000024731	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	SEC24 homolog B, COPII coat complex component.	0.980
SEC24B	SEC16A	ENSANAP00000024731	ENSANAP00000033007	SEC24 homolog B, COPII coat complex component.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.980
YWHAE	LOC105734028	ENSANAP00000016902	ENSANAP00000027112	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.927