STRINGSTRING
JPH1 JPH1 BAX BAX LIME1 LIME1 ITGB3 ITGB3 CAMK2D CAMK2D JPH4 JPH4 NTSR1 NTSR1 ANK2 ANK2 CORO1A CORO1A ENSANAP00000041954 ENSANAP00000041954 CAPN3 CAPN3 CYBA CYBA ENSANAP00000039734 ENSANAP00000039734 F2 F2 CASQ1 CASQ1 TGFB1 TGFB1 JSRP1 JSRP1 JPH2 JPH2 CHD7 CHD7 BDKRB1 BDKRB1 CD19 CD19 CALM3 CALM3 NPSR1 NPSR1 CACNA1C CACNA1C AKAP6 AKAP6 F2RL3 F2RL3 PTK2B PTK2B THY1 THY1 CLIC2 CLIC2 DIAPH1 DIAPH1 GSTO1 GSTO1 PRKD1 PRKD1 PDE4D PDE4D ENSANAP00000030194 ENSANAP00000030194 CX3CL1 CX3CL1 PTPN6 PTPN6 PLN PLN HTT HTT RYR2 RYR2 CALM1 CALM1 TMEM38A TMEM38A ASPH ASPH CXCL9 CXCL9 SLC8A1 SLC8A1 ABL1 ABL1 CXCR3 CXCR3 METTL21C METTL21C CXCL11 CXCL11 PKD2 PKD2 FKBP1B FKBP1B JPH3 JPH3 PLCG1 PLCG1 ENSANAP00000000512 ENSANAP00000000512 GPER1 GPER1 APLNR APLNR P2RY6 P2RY6 TMEM38B TMEM38B NOS1 NOS1 F2R F2R SELENON SELENON TRPC1 TRPC1 PDPK1 PDPK1 HRC HRC UBASH3B UBASH3B LACRT LACRT LYN LYN ENSANAP00000008458 ENSANAP00000008458 CXCL10 CXCL10 SRI SRI ATG5 ATG5 CASQ2 CASQ2 PRKCE PRKCE CEMIP CEMIP DHRS7C DHRS7C DMD DMD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
BAXBCL2 associated X, apoptosis regulator. (193 aa)
LIME1Uncharacterized protein. (291 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
CAMK2DProtein kinase domain-containing protein. (544 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (629 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
ANK2Ankyrin 2. (3962 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
ENSANAP00000041954EF-hand domain-containing protein. (448 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (823 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (193 aa)
ENSANAP00000039734Protein kinase domain-containing protein. (394 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (401 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (378 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (336 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2983 aa)
BDKRB1Bradykinin receptor B1. (282 aa)
CD19CD19 molecule. (565 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (385 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2078 aa)
AKAP6A-kinase anchoring protein 6. (2320 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
THY1Thy-1 cell surface antigen. (161 aa)
CLIC2Chloride intracellular channel 2. (236 aa)
DIAPH1Diaphanous related formin 1. (1281 aa)
GSTO1Glutathione S-transferase omega 1; Belongs to the GST superfamily. (241 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (863 aa)
PDE4DPhosphodiesterase. (748 aa)
ENSANAP00000030194GST N-terminal domain-containing protein. (199 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (395 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (600 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
HTTHuntingtin. (3132 aa)
RYR2Ryanodine receptor 2. (4650 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
TMEM38ATransmembrane protein 38A. (299 aa)
ASPHAspartate beta-hydroxylase. (764 aa)
CXCL9C-X-C motif chemokine. (126 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (367 aa)
METTL21CMethyltransferase like 21C. (264 aa)
CXCL11C-X-C motif chemokine. (96 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (951 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
ENSANAP00000000512Uncharacterized protein. (185 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
TMEM38BTransmembrane protein 38B. (290 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1393 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
SELENONEF-hand domain-containing protein. (540 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (572 aa)
HRCHistidine rich calcium binding protein. (701 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
LACRTLacritin. (137 aa)
LYNLYN proto-oncogene, Src family tyrosine kinase. (498 aa)
ENSANAP00000008458Uncharacterized protein. (1994 aa)
CXCL10C-X-C motif chemokine. (97 aa)
SRIUncharacterized protein. (162 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (404 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CEMIPCell migration inducing hyaluronidase 1. (1267 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
DMDUncharacterized protein. (1243 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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