node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACVR1 | AMH | ENSANAP00000039650 | ENSANAP00000027844 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Anti-Mullerian hormone. | 0.907 |
ACVR1 | AMHR2 | ENSANAP00000039650 | ENSANAP00000031493 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. | 0.935 |
ACVR1 | BMP10 | ENSANAP00000039650 | ENSANAP00000022879 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 10. | 0.880 |
ACVR1 | BMP2 | ENSANAP00000039650 | ENSANAP00000034120 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 2. | 0.982 |
ACVR1 | GDF2 | ENSANAP00000039650 | ENSANAP00000025480 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Growth differentiation factor 2. | 0.909 |
ACVR1 | GDF6 | ENSANAP00000039650 | ENSANAP00000023139 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Growth differentiation factor 6. | 0.711 |
ACVR1 | GDF7 | ENSANAP00000039650 | ENSANAP00000035778 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Growth differentiation factor 7. | 0.781 |
ACVR1 | SMAD7 | ENSANAP00000039650 | ENSANAP00000020600 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.779 |
ACVR1 | TGFB1 | ENSANAP00000039650 | ENSANAP00000036725 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.719 |
ACVR1 | TGFB2 | ENSANAP00000039650 | ENSANAP00000029512 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.591 |
ACVR1 | TGFBR1 | ENSANAP00000039650 | ENSANAP00000011578 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.714 |
ACVR1 | TGFBR2 | ENSANAP00000039650 | ENSANAP00000017484 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.877 |
AMH | ACVR1 | ENSANAP00000027844 | ENSANAP00000039650 | Anti-Mullerian hormone. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.907 |
AMH | AMHR2 | ENSANAP00000027844 | ENSANAP00000031493 | Anti-Mullerian hormone. | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. | 0.946 |
AMH | TGFBR1 | ENSANAP00000027844 | ENSANAP00000011578 | Anti-Mullerian hormone. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.518 |
AMH | TGFBR2 | ENSANAP00000027844 | ENSANAP00000017484 | Anti-Mullerian hormone. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.538 |
AMHR2 | ACVR1 | ENSANAP00000031493 | ENSANAP00000039650 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.935 |
AMHR2 | AMH | ENSANAP00000031493 | ENSANAP00000027844 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. | Anti-Mullerian hormone. | 0.946 |
AMHR2 | BMP2 | ENSANAP00000031493 | ENSANAP00000034120 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. | Bone morphogenetic protein 2. | 0.904 |
AMHR2 | GDF6 | ENSANAP00000031493 | ENSANAP00000023139 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. | Growth differentiation factor 6. | 0.829 |