STRINGSTRING
WNT11 WNT11 ENSANAP00000000168 ENSANAP00000000168 NOG NOG HEY1 HEY1 TGFBR3 TGFBR3 HEYL HEYL SLIT3 SLIT3 SOX11 SOX11 RBM15 RBM15 FZD2 FZD2 FGFRL1 FGFRL1 ROBO1 ROBO1 BMPR1A BMPR1A HEY2 HEY2 TGFBR1 TGFBR1 NKX2-5 NKX2-5 NOTCH1 NOTCH1 SMAD4 SMAD4 TGFBR2 TGFBR2 SMAD7 SMAD7 SAV1 SAV1 PROX1 PROX1 EGLN1 EGLN1 BMPR2 BMPR2 ZFPM2 ZFPM2 WNT5A WNT5A TBX3 TBX3 FGFR2 FGFR2 TGFB2 TGFB2 ROBO2 ROBO2 SLIT2 SLIT2 NSD2 NSD2 BMP4 BMP4 NOS3 NOS3 CITED2 CITED2 ACVR1 ACVR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ENSANAP00000000168Uncharacterized protein. (156 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (376 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
SOX11Transcription factor SOX. (449 aa)
RBM15RNA binding motif protein 15. (978 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
FGFRL1Fibroblast growth factor receptor like 1. (474 aa)
ROBO1Roundabout guidance receptor 1. (1684 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
NKX2-5NK2 homeobox 5. (324 aa)
NOTCH1Notch receptor 1. (2527 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
SMAD7Mothers against decapentaplegic homolog. (489 aa)
SAV1Salvador family WW domain containing protein 1. (413 aa)
PROX1Prospero homeobox 1. (737 aa)
EGLN1Uncharacterized protein. (422 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1019 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TBX3T-box transcription factor 3. (743 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
SLIT2Slit guidance ligand 2. (1541 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1365 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (250 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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