STRINGSTRING
LPAR3 LPAR3 UBAP1 UBAP1 KDM5B KDM5B POU4F2 POU4F2 SEMA3A SEMA3A NIN NIN FGFR2 FGFR2 SPART SPART JADE2 JADE2 EIF2AK4 EIF2AK4 SPAG6 SPAG6 SPRY2 SPRY2 ENSANAP00000026571 ENSANAP00000026571 ULK1 ULK1 IMPACT IMPACT EDN1 EDN1 KIF26B KIF26B WNT5A WNT5A EFNA5 EFNA5 FGF1 FGF1 EDNRA EDNRA ENSANAP00000024200 ENSANAP00000024200 WNT7B WNT7B YAP1 YAP1 HOXD13 HOXD13 SSNA1 SSNA1 DVL1 DVL1 RNF6 RNF6 CDK5 CDK5 MAGI2 MAGI2 PTK7 PTK7 ENSANAP00000021712 ENSANAP00000021712 VCL VCL PAK6 PAK6 TRIM28 TRIM28 PLXNA3 PLXNA3 SALL1 SALL1 TGFBR2 TGFBR2 MST1 MST1 PRKCZ PRKCZ NRN1 NRN1 ENSANAP00000016246 ENSANAP00000016246 IQGAP1 IQGAP1 NOTCH1 NOTCH1 TNR TNR ADPRHL1 ADPRHL1 EMX1 EMX1 SEMA7A SEMA7A ENSANAP00000011886 ENSANAP00000011886 ITGA4 ITGA4 MAP1B MAP1B SOX9 SOX9 WNT11 WNT11 TMEM108 TMEM108 CYFIP1 CYFIP1 C9orf72 C9orf72 ULK2 ULK2 ENSANAP00000008178 ENSANAP00000008178 EXT1 EXT1 EPB41L5 EPB41L5 SFRP1 SFRP1 CDH4 CDH4 WNT3A WNT3A SEMA5A SEMA5A HDAC6 HDAC6 ENSANAP00000006275 ENSANAP00000006275 SFRP2 SFRP2 APP APP EDN3 EDN3 ENSANAP00000005288 ENSANAP00000005288 LAMB2 LAMB2 FLRT1 FLRT1 SPRY1 SPRY1 SLIT3 SLIT3 RYK RYK NRN1L NRN1L S1PR1 S1PR1 FLRT3 FLRT3 LHX2 LHX2 ENSANAP00000002233 ENSANAP00000002233 WASF1 WASF1 LLPH LLPH NDN NDN LZTS2 LZTS2 SRF SRF SLC9A6 SLC9A6 BIN3 BIN3 CSF1 CSF1 RND2 RND2 FGF10 FGF10 STK11 STK11 AURKA AURKA RAPH1 RAPH1 MED1 MED1 POU4F3 POU4F3 ENSANAP00000039808 ENSANAP00000039808 EDN2 EDN2 TBX2 TBX2 ALCAM ALCAM LIMK1 LIMK1 PPP3CB PPP3CB DCX DCX MESP1 MESP1 TNN TNN BMP4 BMP4 TGFB1 TGFB1 MED12 MED12 LOC105728530 LOC105728530 RARG RARG ENSANAP00000035975 ENSANAP00000035975 PLXNA1 PLXNA1 SEMA3F SEMA3F SEMA5B SEMA5B NRP1 NRP1 DCLK1 DCLK1 SLIT2 SLIT2 SPG11 SPG11 RDH10 RDH10 ESR1 ESR1 CTNNB1 CTNNB1 SH3GL2 SH3GL2 LHX1 LHX1 SLIT1 SLIT1 NRP2 NRP2 COBL COBL AREG AREG DDR1 DDR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
UBAP1Ubiquitin associated protein 1. (566 aa)
KDM5BLysine demethylase 5B. (1567 aa)
POU4F2POU domain protein. (353 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (766 aa)
NINNinein. (1913 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
SPARTSpartin. (664 aa)
JADE2Jade family PHD finger 2. (834 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
SPAG6Sperm associated antigen 6. (484 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
ENSANAP00000026571Uncharacterized protein. (128 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1040 aa)
IMPACTImpact RWD domain protein. (321 aa)
EDN1Endothelin 1. (212 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1790 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ENSANAP00000024200Protein kinase domain-containing protein. (279 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (274 aa)
YAP1Uncharacterized protein. (508 aa)
HOXD13Homeobox D13. (344 aa)
SSNA1SS nuclear autoantigen 1. (119 aa)
DVL1Dishevelled segment polarity protein 1. (750 aa)
RNF6Ring finger protein 6. (701 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (314 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1283 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1080 aa)
ENSANAP00000021712Uncharacterized protein. (286 aa)
VCLVinculin. (1134 aa)
PAK6Non-specific serine/threonine protein kinase. (708 aa)
TRIM28Tripartite motif containing 28. (834 aa)
PLXNA3Plexin A3. (1873 aa)
SALL1Spalt like transcription factor 1. (1322 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
PRKCZProtein kinase C. (594 aa)
NRN1Neuritin 1. (168 aa)
ENSANAP00000016246BAR domain-containing protein. (225 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
NOTCH1Notch receptor 1. (2527 aa)
TNRTenascin R. (1358 aa)
ADPRHL1ADP-ribosylhydrolase like 1. (354 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (654 aa)
ENSANAP00000011886Uncharacterized protein. (350 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1010 aa)
MAP1BMicrotubule associated protein 1B. (2465 aa)
SOX9SRY-box transcription factor 9. (505 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TMEM108Transmembrane protein 108. (577 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
ULK2Unc-51 like autophagy activating kinase 2. (593 aa)
ENSANAP00000008178Uncharacterized protein. (65 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (822 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SEMA5ASemaphorin 5A. (1074 aa)
HDAC6Histone deacetylase 6. (1226 aa)
ENSANAP00000006275Uncharacterized protein. (133 aa)
SFRP2Secreted frizzled related protein 2. (296 aa)
APPAmyloid beta precursor protein. (741 aa)
EDN3Endothelin 3. (230 aa)
ENSANAP00000005288Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (397 aa)
LAMB2Laminin subunit beta 2. (1816 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (674 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
RYKReceptor like tyrosine kinase. (599 aa)
NRN1LNeuritin 1 like. (167 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
LHX2LIM homeobox 2. (406 aa)
ENSANAP00000002233Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (243 aa)
WASF1WASP family member 1. (559 aa)
LLPHUncharacterized protein. (129 aa)
NDNNecdin, MAGE family member. (321 aa)
LZTS2Leucine zipper tumor suppressor 2. (600 aa)
SRFSerum response factor. (509 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa)
BIN3BAR domain-containing protein. (257 aa)
CSF1Colony stimulating factor 1. (619 aa)
RND2Rho family GTPase 2. (227 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
AURKAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (401 aa)
RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (1305 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
POU4F3POU domain protein. (338 aa)
ENSANAP00000039808Uncharacterized protein. (156 aa)
EDN2Endothelin 2. (178 aa)
TBX2T-box transcription factor 2. (713 aa)
ALCAMActivated leukocyte cell adhesion molecule. (583 aa)
LIMK1LIM domain kinase 1. (593 aa)
PPP3CBSerine/threonine-protein phosphatase. (439 aa)
DCXDoublecortin. (400 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (260 aa)
TNNTenascin N. (1298 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (378 aa)
MED12Mediator complex subunit 12. (2177 aa)
LOC105728530Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (390 aa)
RARGRetinoic acid receptor gamma. (456 aa)
ENSANAP00000035975Uncharacterized protein. (121 aa)
PLXNA1Plexin A1. (1911 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
SEMA5BSemaphorin 5B. (1077 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
DCLK1Uncharacterized protein. (740 aa)
SLIT2Slit guidance ligand 2. (1541 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2437 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
CTNNB1Catenin beta 1. (781 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (344 aa)
LHX1LIM homeobox 1. (406 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
COBLCordon-bleu WH2 repeat protein. (1294 aa)
AREGAmphiregulin. (252 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (913 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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