STRINGSTRING
TMPRSS3 TMPRSS3 STIM2 STIM2 RRAD RRAD VTI1B VTI1B KCNMB3 KCNMB3 RASA1 RASA1 CALM1 CALM1 CABP2 CABP2 COMMD1 COMMD1 ENSANAP00000025969 ENSANAP00000025969 RSC1A1 RSC1A1 GRM2 GRM2 LOC105707120 LOC105707120 LOC105734028 LOC105734028 KCNAB1 KCNAB1 SUMO1 SUMO1 CRISP1 CRISP1 ATP2B4 ATP2B4 NEDD4 NEDD4 REM1 REM1 SLC30A1 SLC30A1 PRSS8 PRSS8 PHPT1 PHPT1 BSND BSND KCNMB1 KCNMB1 FXYD5 FXYD5 STX7 STX7 CALM3 CALM3 TNNI3 TNNI3 SCN4B SCN4B KCNMB4 KCNMB4 CRISP3 CRISP3 DRD4 DRD4 AKAP9 AKAP9 CABP5 CABP5 WNK4 WNK4 CACNG1 CACNG1 DPP10 DPP10 KCNS1 KCNS1 ENSANAP00000039734 ENSANAP00000039734 MUSTN1 MUSTN1 STX1A STX1A PTPN3 PTPN3 SCN3B SCN3B STIM1 STIM1 CACNG4 CACNG4 KCNS3 KCNS3 AMIGO2 AMIGO2 FXYD1 FXYD1 SLC9A3R1 SLC9A3R1 KCNE3 KCNE3 FXYD7 FXYD7 KCNIP1 KCNIP1 CFTR CFTR ENSANAP00000002902 ENSANAP00000002902 PIAS3 PIAS3 AMIGO1 AMIGO1 FGF12 FGF12 LRRC55 LRRC55 CACNG6 CACNG6 NOS1 NOS1 KCNIP2 KCNIP2 KCNIP4 KCNIP4 PKP2 PKP2 SNTA1 SNTA1 FGF14 FGF14 PRSS41 PRSS41 ENSANAP00000007251 ENSANAP00000007251 CACNG7 CACNG7 NRXN1 NRXN1 SCN1B SCN1B AMBP AMBP VAMP8 VAMP8 CRISP2 CRISP2 SGK2 SGK2 ENSANAP00000010339 ENSANAP00000010339 WNK3 WNK3 WNK2 WNK2 DPP6 DPP6 CACNB3 CACNB3 REM2 REM2 LOC105714684 LOC105714684 PCSK9 PCSK9 CABP1 CABP1 FGF13 FGF13 RANGRF RANGRF ENSANAP00000013465 ENSANAP00000013465 ENSANAP00000013528 ENSANAP00000013528 LOC105722914 LOC105722914 CABP4 CABP4 STX8 STX8 ENSANAP00000014912 ENSANAP00000014912 DLG1 DLG1 ADRB2 ADRB2 HPCAL4 HPCAL4 PRKG1 PRKG1 PRKCZ PRKCZ PDZD4 PDZD4 GPLD1 GPLD1 YWHAE YWHAE LRRC38 LRRC38 CACNG8 CACNG8 PDZD3 PDZD3 FXYD4 FXYD4 KCNIP3 KCNIP3 KCNAB2 KCNAB2 ENSANAP00000018110 ENSANAP00000018110 WNK1 WNK1 ARPP19 ARPP19 KCNK2 KCNK2 FXYD3 FXYD3 MCUB MCUB FGF11 FGF11 CHRNA7 CHRNA7 AKT1 AKT1 VAMP5 VAMP5 CAV3 CAV3 PRKCB PRKCB CAMK2D CAMK2D CNTD1 CNTD1 ITPR1 ITPR1 STOML1 STOML1 TRPV1 TRPV1 SCLT1 SCLT1 CAV1 CAV1 ENSANAP00000021042 ENSANAP00000021042 ENSANAP00000021521 ENSANAP00000021521 NRXN2 NRXN2 SCN2B SCN2B FKBP1B FKBP1B LOC105709173 LOC105709173 LRRC52 LRRC52 NRXN3 NRXN3 GRM3 GRM3 ABCC9 ABCC9 KCNE4 KCNE4 KCNMB2 KCNMB2 ENSA ENSA PACSIN3 PACSIN3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (460 aa)
STIM2Stromal interaction molecule 2. (754 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (293 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (216 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (257 aa)
RASA1RAS p21 protein activator 1. (1049 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
CABP2Calcium binding protein 2. (220 aa)
COMMD1Copper metabolism domain containing 1. (190 aa)
ENSANAP00000025969FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (62 aa)
RSC1A1Regulator of solute carriers 1. (646 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
LOC105707120Uncharacterized protein. (824 aa)
LOC10573402814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
CRISP1Cysteine rich secretory protein 1; Belongs to the CRISP family. (249 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1025 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1292 aa)
REM1RRAD and GEM like GTPase 1. (266 aa)
SLC30A1Solute carrier family 30 member 1. (507 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (344 aa)
PHPT1Phosphohistidine phosphatase 1. (124 aa)
BSNDBarttin CLCNK type accessory beta subunit. (319 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
FXYD5FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (220 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (255 aa)
KCNMB4Uncharacterized protein. (210 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (276 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (407 aa)
AKAP9A-kinase anchoring protein 9. (3897 aa)
CABP5Calcium binding protein 5. (125 aa)
WNK4WNK lysine deficient protein kinase 4. (1229 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (716 aa)
KCNS1Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily. (529 aa)
ENSANAP00000039734Protein kinase domain-containing protein. (394 aa)
MUSTN1Uncharacterized protein. (87 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (292 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (962 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
STIM1Stromal interaction molecule 1. (790 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (105 aa)
FXYD7FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (115 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (246 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1226 aa)
ENSANAP00000002902Uncharacterized protein. (232 aa)
PIAS3Uncharacterized protein. (628 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
LRRC55Leucine rich repeat containing 55. (316 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1393 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (307 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (250 aa)
PKP2Plakophilin 2. (842 aa)
SNTA1Syntrophin alpha 1. (505 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
PRSS41Serine protease 41; Belongs to the peptidase S1 family. (294 aa)
ENSANAP00000007251Uncharacterized protein. (86 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (306 aa)
NRXN1Neurexin 1. (1507 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (215 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (352 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
CRISP2Cysteine rich secretory protein 2; Belongs to the CRISP family. (243 aa)
SGK2Non-specific serine/threonine protein kinase. (411 aa)
ENSANAP00000010339MCU domain-containing protein. (296 aa)
WNK3WNK lysine deficient protein kinase 3. (1717 aa)
WNK2WNK lysine deficient protein kinase 2. (2258 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (810 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
LOC105714684Uncharacterized protein. (591 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (690 aa)
CABP1Calcium binding protein 1. (358 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
ENSANAP00000013465Small ubiquitin-related modifier. (108 aa)
ENSANAP00000013528FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)
LOC105722914Uncharacterized protein. (294 aa)
CABP4Calcium binding protein 4. (246 aa)
STX8Syntaxin 8. (263 aa)
ENSANAP00000014912Small ubiquitin-related modifier. (75 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
ADRB2Adrenoceptor beta 2. (426 aa)
HPCAL4Hippocalcin like 4. (191 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
PRKCZProtein kinase C. (594 aa)
PDZD4PDZ domain containing 4. (777 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
LRRC38Leucine rich repeat containing 38. (298 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (349 aa)
PDZD3PDZ domain containing 3. (571 aa)
FXYD4FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (257 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (405 aa)
ENSANAP00000018110Ion_trans domain-containing protein. (466 aa)
WNK1WNK lysine deficient protein kinase 1. (2831 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (130 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (145 aa)
MCUBMCU domain-containing protein. (336 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
CHRNA7Uncharacterized protein. (537 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
VAMP5Vesicle associated membrane protein 5. (115 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CAMK2DProtein kinase domain-containing protein. (544 aa)
CNTD1Cyclin N-terminal domain containing 1. (330 aa)
ITPR1Uncharacterized protein. (1010 aa)
STOML1Stomatin like 1. (398 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (798 aa)
SCLT1Sodium channel and clathrin linker 1. (688 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
ENSANAP00000021042Uncharacterized protein. (136 aa)
ENSANAP00000021521Rad60-SLD domain-containing protein. (94 aa)
NRXN2Neurexin 2. (1704 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
LOC105709173Uncharacterized protein. (2229 aa)
LRRC52Leucine rich repeat containing 52. (313 aa)
NRXN3Neurexin 3. (1664 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (217 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (263 aa)
ENSAUncharacterized protein. (132 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (465 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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