Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGER | APP | ENSANAP00000031416 | ENSANAP00000006013 | Advanced glycosylation end-product specific receptor. | Amyloid beta precursor protein. | 0.669 |
| AGER | IL1B | ENSANAP00000031416 | ENSANAP00000000520 | Advanced glycosylation end-product specific receptor. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.434 |
| AGER | RELA | ENSANAP00000031416 | ENSANAP00000036604 | Advanced glycosylation end-product specific receptor. | RELA proto-oncogene, NF-kB subunit. | 0.420 |
| APP | AGER | ENSANAP00000006013 | ENSANAP00000031416 | Amyloid beta precursor protein. | Advanced glycosylation end-product specific receptor. | 0.669 |
| APP | CALR | ENSANAP00000006013 | ENSANAP00000006562 | Amyloid beta precursor protein. | Calreticulin. | 0.742 |
| APP | EGFR | ENSANAP00000006013 | ENSANAP00000037076 | Amyloid beta precursor protein. | Epidermal growth factor receptor. | 0.534 |
| APP | EP300 | ENSANAP00000006013 | ENSANAP00000015649 | Amyloid beta precursor protein. | E1A binding protein p300. | 0.536 |
| APP | IL1B | ENSANAP00000006013 | ENSANAP00000000520 | Amyloid beta precursor protein. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.434 |
| APP | TNF | ENSANAP00000006013 | ENSANAP00000029597 | Amyloid beta precursor protein. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.428 |
| APP | TREM2 | ENSANAP00000006013 | ENSANAP00000036261 | Amyloid beta precursor protein. | Triggering receptor expressed on myeloid cells 2. | 0.522 |
| CALR | APP | ENSANAP00000006562 | ENSANAP00000006013 | Calreticulin. | Amyloid beta precursor protein. | 0.742 |
| CD14 | TLR3 | ENSANAP00000034161 | ENSANAP00000009875 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] | Toll like receptor 3; Belongs to the Toll-like receptor family. | 0.553 |
| CD14 | TLR7 | ENSANAP00000034161 | ENSANAP00000026575 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] | Toll like receptor 7; Belongs to the Toll-like receptor family. | 0.548 |
| CD14 | TRAF6 | ENSANAP00000034161 | ENSANAP00000020369 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.430 |
| CD27 | CD86 | ENSANAP00000038705 | ENSANAP00000012264 | CD27 molecule. | CD86 molecule. | 0.583 |
| CD86 | CD27 | ENSANAP00000012264 | ENSANAP00000038705 | CD86 molecule. | CD27 molecule. | 0.583 |
| CD86 | HAVCR2 | ENSANAP00000012264 | ENSANAP00000024607 | CD86 molecule. | Hepatitis A virus cellular receptor 2. | 0.559 |
| CD86 | IL18 | ENSANAP00000012264 | ENSANAP00000028062 | CD86 molecule. | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. | 0.459 |
| CD86 | IL1B | ENSANAP00000012264 | ENSANAP00000000520 | CD86 molecule. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.608 |
| CD86 | TLR3 | ENSANAP00000012264 | ENSANAP00000009875 | CD86 molecule. | Toll like receptor 3; Belongs to the Toll-like receptor family. | 0.576 |
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