22 items (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
	GNA13	G protein subunit alpha 13. (325 aa)
	PRKG1	cGMP-dependent protein kinase. (686 aa)
	RBM10	Uncharacterized protein. (1003 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (244 aa)
	GNA12	G protein subunit alpha 12. (380 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	CCDC142	Coiled-coil domain containing 142. (745 aa)
	PDCD4	Programmed cell death 4. (469 aa)
	LOC105726267	Uncharacterized protein. (920 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	TAFA5	TAFA chemokine like family member 5. (132 aa)
	CNN1	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (299 aa)
	CDKN1B	Cyclin dependent kinase inhibitor 1B. (205 aa)
	EFEMP2	EGF containing fibulin extracellular matrix protein 2. (443 aa)
	CDKN1A	Cyclin dependent kinase inhibitor 1A. (158 aa)
	MYOCD	Myocardin. (984 aa)
	MEF2C	Myocyte enhancer factor 2C. (490 aa)
	NDRG2	NDRG family member 2. (371 aa)
	S1PR2	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	IL10	Interleukin 10. (178 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	IL10	ENSANAP00000019740	ENSANAP00000005430	Adiponectin, C1Q and collagen domain containing.	Interleukin 10.	0.443
CDKN1A	CDKN1B	ENSANAP00000039820	ENSANAP00000036709	Cyclin dependent kinase inhibitor 1A.	Cyclin dependent kinase inhibitor 1B.	0.948
CDKN1B	CDKN1A	ENSANAP00000036709	ENSANAP00000039820	Cyclin dependent kinase inhibitor 1B.	Cyclin dependent kinase inhibitor 1A.	0.948
CDKN1B	PTEN	ENSANAP00000036709	ENSANAP00000031376	Cyclin dependent kinase inhibitor 1B.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.426
CNN1	MYOCD	ENSANAP00000035005	ENSANAP00000039968	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Myocardin.	0.450
GNA12	GNA13	ENSANAP00000021561	ENSANAP00000013993	G protein subunit alpha 12.	G protein subunit alpha 13.	0.954
GNA12	S1PR2	ENSANAP00000021561	ENSANAP00000002230	G protein subunit alpha 12.	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.979
GNA13	GNA12	ENSANAP00000013993	ENSANAP00000021561	G protein subunit alpha 13.	G protein subunit alpha 12.	0.954
GNA13	S1PR2	ENSANAP00000013993	ENSANAP00000002230	G protein subunit alpha 13.	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.989
IL10	ADIPOQ	ENSANAP00000005430	ENSANAP00000019740	Interleukin 10.	Adiponectin, C1Q and collagen domain containing.	0.443
MEF2C	MYOCD	ENSANAP00000040463	ENSANAP00000039968	Myocyte enhancer factor 2C.	Myocardin.	0.432
MYOCD	CNN1	ENSANAP00000039968	ENSANAP00000035005	Myocardin.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.450
MYOCD	MEF2C	ENSANAP00000039968	ENSANAP00000040463	Myocardin.	Myocyte enhancer factor 2C.	0.432
PDCD4	PTEN	ENSANAP00000027974	ENSANAP00000031376	Programmed cell death 4.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.578
PTEN	CDKN1B	ENSANAP00000031376	ENSANAP00000036709	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Cyclin dependent kinase inhibitor 1B.	0.426
PTEN	PDCD4	ENSANAP00000031376	ENSANAP00000027974	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Programmed cell death 4.	0.578
S1PR2	GNA12	ENSANAP00000002230	ENSANAP00000021561	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 12.	0.979
S1PR2	GNA13	ENSANAP00000002230	ENSANAP00000013993	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 13.	0.989