STRINGSTRING
IFI27 IFI27 MAPK7 MAPK7 EYA3 EYA3 ENSANAP00000012403 ENSANAP00000012403 ENSANAP00000011886 ENSANAP00000011886 TGFBR1 TGFBR1 CTTN CTTN COL2A1 COL2A1 IL1B IL1B LOC105725379 LOC105725379 ITPRIPL2 ITPRIPL2 ENSANAP00000001352 ENSANAP00000001352 THBS1 THBS1 SIAH2 SIAH2 IL7 IL7 GAS1 GAS1 CSF2 CSF2 BRCA1 BRCA1 TMBIM1 TMBIM1 LOC105729267 LOC105729267 EYA2 EYA2 ENSANAP00000005208 ENSANAP00000005208 LGALS3 LGALS3 ITGAV ITGAV SFRP2 SFRP2 SNAI2 SNAI2 ITGA6 ITGA6 MCL1 MCL1 IL19 IL19 ZC3HC1 ZC3HC1 FAIM FAIM ENSANAP00000009508 ENSANAP00000009508 SERPINE1 SERPINE1 IGF1 IGF1 LOC105721445 LOC105721445 EYA4 EYA4 PSME3 PSME3 ARHGEF2 ARHGEF2 FGF10 FGF10 AGAP2 AGAP2 PHIP PHIP ENSANAP00000039808 ENSANAP00000039808 ACVR1 ACVR1 TCF7L2 TCF7L2 GCLC GCLC NOS3 NOS3 BMP4 BMP4 RELA RELA ENSANAP00000035262 ENSANAP00000035262 ITPRIP ITPRIP NRP1 NRP1 IFI6 IFI6 LOC105733239 LOC105733239 SRC SRC PAK5 PAK5 RIPK1 RIPK1 PARK7 PARK7 FGB FGB BCL2L1 BCL2L1 BCL2 BCL2 AR AR PELI3 PELI3 TNF TNF ENSANAP00000029484 ENSANAP00000029484 HMOX1 HMOX1 TERT TERT GATA1 GATA1 NRG1 NRG1 CX3CL1 CX3CL1 GSTP1 GSTP1 HTT HTT GCLM GCLM GFRAL GFRAL CTNNA1 CTNNA1 FGG FGG ENSANAP00000023720 ENSANAP00000023720 YAP1 YAP1 RB1CC1 RB1CC1 TNFAIP3 TNFAIP3 ENSANAP00000022162 ENSANAP00000022162 LMNA LMNA HGF HGF SH3RF1 SH3RF1 NOL3 NOL3 LOC105709597 LOC105709597 GDNF GDNF AKT1 AKT1 STRADB STRADB EYA1 EYA1 FAIM2 FAIM2 ZMYND11 ZMYND11 RNF34 RNF34 LOC105725714 LOC105725714 MAP2K5 MAP2K5 BMP5 BMP5 GSK3B GSK3B RPS6KB1 RPS6KB1 LOC105705221 LOC105705221 BIRC6 BIRC6 UNC5B UNC5B RFFL RFFL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFI27Interferon alpha inducible protein 27. (107 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (572 aa)
ENSANAP00000012403RING-type domain-containing protein. (175 aa)
ENSANAP00000011886Uncharacterized protein. (350 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
CTTNCortactin. (570 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
LOC105725379C-X-C motif chemokine. (102 aa)
ITPRIPL2ITPRIP like 2. (535 aa)
ENSANAP00000001352RING-type domain-containing protein. (181 aa)
THBS1Thrombospondin 1. (1173 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
GAS1Growth arrest specific 1. (342 aa)
CSF2Colony stimulating factor 2. (144 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1827 aa)
TMBIM1Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (311 aa)
LOC105729267Uncharacterized protein. (238 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (543 aa)
ENSANAP00000005208DJ-1_PfpI domain-containing protein. (70 aa)
LGALS3Galectin. (275 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1016 aa)
SFRP2Secreted frizzled related protein 2. (296 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (352 aa)
IL19Interleukin 19. (214 aa)
ZC3HC1Zinc finger C3HC-type containing 1. (503 aa)
FAIMFas apoptotic inhibitory molecule. (204 aa)
ENSANAP00000009508Fib_alpha domain-containing protein. (287 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (366 aa)
IGF1Insulin like growth factor 1. (201 aa)
LOC105721445Uncharacterized protein. (244 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (650 aa)
PSME3Proteasome activator subunit 3. (267 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1175 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1193 aa)
PHIPPleckstrin homology domain interacting protein. (1821 aa)
ENSANAP00000039808Uncharacterized protein. (156 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TCF7L2Transcription factor 7 like 2. (618 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
RELARELA proto-oncogene, NF-kB subunit. (540 aa)
ENSANAP00000035262Uncharacterized protein. (134 aa)
ITPRIPInositol 1,4,5-trisphosphate receptor interacting protein. (536 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
IFI6Interferon alpha inducible protein 6. (137 aa)
LOC105733239Uncharacterized protein. (916 aa)
SRCTyrosine-protein kinase. (542 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
PARK7DJ-1_PfpI domain-containing protein. (189 aa)
FGBFibrinogen beta chain. (488 aa)
BCL2L1BCL2 like 1. (233 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
ARAndrogen receptor. (887 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
ENSANAP00000029484Uncharacterized protein. (182 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1095 aa)
GATA1GATA binding protein 1. (413 aa)
NRG1Neuregulin 1. (713 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (395 aa)
GSTP1Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa)
HTTHuntingtin. (3132 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
GFRALGDNF family receptor alpha like. (394 aa)
CTNNA1Catenin alpha 1. (945 aa)
FGGFibrinogen gamma chain. (453 aa)
ENSANAP00000023720Uncharacterized protein. (108 aa)
YAP1Uncharacterized protein. (508 aa)
RB1CC1RB1 inducible coiled-coil 1. (1562 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
ENSANAP00000022162Uncharacterized protein. (163 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
SH3RF1SH3 domain containing ring finger 1. (889 aa)
NOL3Nucleolar protein 3. (266 aa)
LOC105709597Uncharacterized protein. (530 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
STRADBSTE20 related adaptor beta. (423 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
FAIM2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa)
ZMYND11Uncharacterized protein. (617 aa)
RNF34RING-type domain-containing protein. (495 aa)
LOC105725714DJ-1_PfpI domain-containing protein. (181 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (415 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC105705221DJ-1_PfpI domain-containing protein. (175 aa)
BIRC6Baculoviral IAP repeat containing 6. (4889 aa)
UNC5BUnc-5 netrin receptor B. (946 aa)
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (384 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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