STRINGSTRING
LDLRAP1 LDLRAP1 KDELR1 KDELR1 COPZ2 COPZ2 TSGA13 TSGA13 DNAJC5 DNAJC5 AP2A2 AP2A2 KIAA0319 KIAA0319 SEC31A SEC31A AVPR2 AVPR2 NECAP1 NECAP1 EPN3 EPN3 FZD2 FZD2 ENSANAP00000005848 ENSANAP00000005848 KDELR2 KDELR2 FZD4 FZD4 WDR86 WDR86 LOC105718792 LOC105718792 AP1M1 AP1M1 LOC105717178 LOC105717178 COPG2 COPG2 AP2B1 AP2B1 EPGN EPGN COPB2 COPB2 AP1G1 AP1G1 ENTHD1 ENTHD1 DAB2 DAB2 LOC105725485 LOC105725485 ATP6V0B ATP6V0B AVP AVP DIPK2A DIPK2A RAB35 RAB35 ENSANAP00000037159 ENSANAP00000037159 CNIH3 CNIH3 LMAN1 LMAN1 AP3B1 AP3B1 IL7R IL7R DENND1A DENND1A CGREF1 CGREF1 NCALD NCALD TEPSIN TEPSIN SEC16A SEC16A SEC31B SEC31B ENSANAP00000000736 ENSANAP00000000736 TF TF FZD5 FZD5 RASSF10 RASSF10 AP1B1 AP1B1 MCFD2 MCFD2 SCAP SCAP EPN2 EPN2 COPE COPE LOC105714732 LOC105714732 LOC105722139 LOC105722139 KLHL12 KLHL12 CNIH2 CNIH2 SEC24A SEC24A SH3GL2 SH3GL2 SCARB2 SCARB2 ATP6V1A ATP6V1A SYNRG SYNRG AREG AREG CD59 CD59 AP1G2 AP1G2 ARCN1 ARCN1 AFTPH AFTPH SAR1B SAR1B ENSANAP00000029929 ENSANAP00000029929 SEC24C SEC24C GAD1 GAD1 EREG EREG PEF1 PEF1 CLINT1 CLINT1 COPZ1 COPZ1 IGF2R IGF2R M6PR M6PR CLBA1 CLBA1 SLC18A3 SLC18A3 VAMP4 VAMP4 SAR1A SAR1A GAD2 GAD2 ATP6V0C ATP6V0C RASSF9 RASSF9 SCYL1 SCYL1 WNT5A WNT5A TGFA TGFA TFRC TFRC SEC24B SEC24B VMA21 VMA21 NECAP2 NECAP2 PDCD6 PDCD6 CD9 CD9 STX5 STX5 SEC23A SEC23A SEC24D SEC24D EGF EGF EPN1 EPN1 ENSANAP00000018891 ENSANAP00000018891 AP3B2 AP3B2 ATP6V1D ATP6V1D SYNJ2 SYNJ2 LOC105728056 LOC105728056 HIP1R HIP1R LOC105730572 LOC105730572 HBEGF HBEGF TMEM199 TMEM199 ENSANAP00000015320 ENSANAP00000015320 ADRB2 ADRB2 ENSANAP00000014453 ENSANAP00000014453 BTC BTC SLC2A8 SLC2A8 AP2S1 AP2S1 ENSANAP00000013734 ENSANAP00000013734 ROR2 ROR2 AP1M2 AP1M2 CEMIP CEMIP KDELR3 KDELR3 AP2A1 AP2A1 SLC18A2 SLC18A2 ENSANAP00000012036 ENSANAP00000012036 COPA COPA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
KDELR1ER lumen protein-retaining receptor. (212 aa)
COPZ2Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (210 aa)
TSGA13Testis specific 13. (275 aa)
DNAJC5J domain-containing protein. (198 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
KIAA0319KIAA0319. (1043 aa)
SEC31ASEC31 homolog A, COPII coat complex component. (1226 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
NECAP1NECAP endocytosis associated 1. (275 aa)
EPN3Epsin 3. (640 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
ENSANAP00000005848AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
KDELR2ER lumen protein-retaining receptor. (347 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
WDR86WD repeat domain 86. (464 aa)
LOC105718792J domain-containing protein. (196 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (469 aa)
LOC105717178V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
COPG2Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (871 aa)
AP2B1Uncharacterized protein. (928 aa)
EPGNEpithelial mitogen. (154 aa)
COPB2Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (906 aa)
AP1G1AP-1 complex subunit gamma. (830 aa)
ENTHD1ENTH domain containing 1. (610 aa)
DAB2DAB adaptor protein 2. (552 aa)
LOC105725485AP complex subunit beta. (903 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (252 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
DIPK2ADivergent protein kinase domain 2A. (430 aa)
RAB35RAB35, member RAS oncogene family. (214 aa)
ENSANAP00000037159WD_REPEATS_REGION domain-containing protein. (508 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (160 aa)
LMAN1Lectin, mannose binding 1. (518 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
IL7RInterleukin 7 receptor. (459 aa)
DENND1ADENN domain containing 1A. (1013 aa)
CGREF1Cell growth regulator with EF-hand domain 1. (379 aa)
NCALDNeurocalcin delta. (193 aa)
TEPSINTEPSIN adaptor related protein complex 4 accessory protein. (589 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2225 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1184 aa)
ENSANAP00000000736Uncharacterized protein. (229 aa)
TFUncharacterized protein; Belongs to the transferrin family. (699 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
RASSF10Ras association domain family member 10. (504 aa)
AP1B1AP complex subunit beta. (769 aa)
MCFD2Multiple coagulation factor deficiency 2. (146 aa)
SCAPUncharacterized protein. (1241 aa)
EPN2Epsin 2. (641 aa)
COPECoatomer protein complex subunit epsilon. (332 aa)
LOC105714732V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (112 aa)
LOC105722139Uncharacterized protein. (250 aa)
KLHL12Kelch like family member 12. (564 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
SEC24ASEC24 homolog A, COPII coat complex component. (975 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (344 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (618 aa)
SYNRGSynergin gamma. (1253 aa)
AREGAmphiregulin. (252 aa)
CD59UPAR/Ly6 domain-containing protein. (128 aa)
AP1G2AP-1 complex subunit gamma. (785 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (550 aa)
AFTPHAftiphilin. (935 aa)
SAR1BSecretion associated Ras related GTPase 1B. (165 aa)
ENSANAP00000029929Uncharacterized protein. (890 aa)
SEC24CUncharacterized protein. (1118 aa)
GAD1Glutamate decarboxylase 1. (676 aa)
EREGEpiregulin. (161 aa)
PEF1Uncharacterized protein. (284 aa)
CLINT1Clathrin interactor 1. (643 aa)
COPZ1Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (197 aa)
IGF2RInsulin like growth factor 2 receptor. (2480 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (337 aa)
CLBA1Clathrin binding box of aftiphilin containing 1. (325 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
RASSF9Ras association domain family member 9. (435 aa)
SCYL1SCY1 like pseudokinase 1. (808 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TGFATransforming growth factor alpha. (165 aa)
TFRCTransferrin receptor. (680 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1283 aa)
VMA21Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. (120 aa)
NECAP2NECAP endocytosis associated 2. (271 aa)
PDCD6Programmed cell death 6. (159 aa)
CD9Tetraspanin. (247 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (361 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
SEC24DSEC24 homolog D, COPII coat complex component. (1038 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
EPN1Epsin 1. (655 aa)
ENSANAP00000018891Uncharacterized protein. (102 aa)
AP3B2AP-3 complex subunit beta. (1101 aa)
ATP6V1DATPase H+ transporting V1 subunit D. (247 aa)
SYNJ2Synaptojanin 2. (1497 aa)
LOC105728056Ig-like domain-containing protein; Belongs to the MHC class I family. (408 aa)
HIP1RHuntingtin interacting protein 1 related. (1129 aa)
LOC105730572DUF1681 domain-containing protein. (262 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
TMEM199Transmembrane protein 199. (208 aa)
ENSANAP00000015320AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (401 aa)
ADRB2Adrenoceptor beta 2. (426 aa)
ENSANAP00000014453DUF1681 domain-containing protein. (264 aa)
BTCBetacellulin. (138 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (404 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
ENSANAP00000013734Uncharacterized protein. (502 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (899 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (385 aa)
CEMIPCell migration inducing hyaluronidase 1. (1267 aa)
KDELR3ER lumen protein-retaining receptor. (228 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
ENSANAP00000012036Adaptin_N domain-containing protein. (130 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1231 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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