77 items (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EPGN	Epithelial mitogen. (154 aa)
	AP1G1	AP-1 complex subunit gamma. (830 aa)
	ENTHD1	ENTH domain containing 1. (610 aa)
	DAB2	DAB adaptor protein 2. (552 aa)
	LOC105725485	AP complex subunit beta. (903 aa)
	ATP6V0B	ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (252 aa)
	AVP	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
	RAB35	RAB35, member RAS oncogene family. (214 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
	IL7R	Interleukin 7 receptor. (459 aa)
	DENND1A	DENN domain containing 1A. (1013 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (344 aa)
	SCARB2	Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)
	ATP6V1A	ATPase H+ transporting V1 subunit A. (618 aa)
	SYNRG	Synergin gamma. (1253 aa)
	AREG	Amphiregulin. (252 aa)
	AP1G2	AP-1 complex subunit gamma. (785 aa)
	AFTPH	Aftiphilin. (935 aa)
	ENSANAP00000029929	Uncharacterized protein. (890 aa)
	GAD1	Glutamate decarboxylase 1. (676 aa)
	EREG	Epiregulin. (161 aa)
	CLINT1	Clathrin interactor 1. (643 aa)
	IGF2R	Insulin like growth factor 2 receptor. (2480 aa)
	M6PR	Mannose-6-phosphate receptor, cation dependent. (337 aa)
	CLBA1	Clathrin binding box of aftiphilin containing 1. (325 aa)
	SLC18A3	Solute carrier family 18 member A3. (532 aa)
	VAMP4	Vesicle associated membrane protein 4. (141 aa)
	GAD2	Glutamate decarboxylase 2. (585 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	RASSF9	Ras association domain family member 9. (435 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	TGFA	Transforming growth factor alpha. (165 aa)
	TFRC	Transferrin receptor. (680 aa)
	NECAP2	NECAP endocytosis associated 2. (271 aa)
	CD9	Tetraspanin. (247 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
	EPN1	Epsin 1. (655 aa)
	AP3B2	AP-3 complex subunit beta. (1101 aa)
	ATP6V1D	ATPase H+ transporting V1 subunit D. (247 aa)
	SYNJ2	Synaptojanin 2. (1497 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1129 aa)
	LOC105730572	DUF1681 domain-containing protein. (262 aa)
	HBEGF	Heparin binding EGF like growth factor. (208 aa)
	ENSANAP00000015320	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (401 aa)
	ADRB2	Adrenoceptor beta 2. (426 aa)
	ENSANAP00000014453	DUF1681 domain-containing protein. (264 aa)
	BTC	Betacellulin. (138 aa)
	SLC2A8	Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (404 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	ROR2	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (899 aa)
	AP1M2	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (385 aa)
	CEMIP	Cell migration inducing hyaluronidase 1. (1267 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
	SLC18A2	Solute carrier family 18 member A2. (517 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (308 aa)
	DNAJC5	J domain-containing protein. (198 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
	KIAA0319	KIAA0319. (1043 aa)
	AVPR2	Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
	NECAP1	NECAP endocytosis associated 1. (275 aa)
	EPN3	Epsin 3. (640 aa)
	FZD2	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
	ENSANAP00000005848	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
	FZD4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
	LOC105718792	J domain-containing protein. (196 aa)
	AP1M1	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (469 aa)
	LOC105717178	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	AP2B1	Uncharacterized protein. (928 aa)
	LOC105714732	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (112 aa)
	EPN2	Epsin 2. (641 aa)
	AP1B1	AP complex subunit beta. (769 aa)
	RASSF10	Ras association domain family member 10. (504 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	TF	Uncharacterized protein; Belongs to the transferrin family. (699 aa)
	ENSANAP00000000736	Uncharacterized protein. (229 aa)
	NCALD	Neurocalcin delta. (193 aa)
	CGREF1	Cell growth regulator with EF-hand domain 1. (379 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRB2	AVP	ENSANAP00000015275	ENSANAP00000039277	Adrenoceptor beta 2.	Arginine vasopressin; Belongs to the vasopressin/oxytocin family.	0.425
ADRB2	AVPR2	ENSANAP00000015275	ENSANAP00000008955	Adrenoceptor beta 2.	Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.403
AFTPH	AP1B1	ENSANAP00000030857	ENSANAP00000002345	Aftiphilin.	AP complex subunit beta.	0.420
AFTPH	AP1G1	ENSANAP00000030857	ENSANAP00000041879	Aftiphilin.	AP-1 complex subunit gamma.	0.476
AFTPH	AP1G2	ENSANAP00000030857	ENSANAP00000031284	Aftiphilin.	AP-1 complex subunit gamma.	0.509
AFTPH	AP1M1	ENSANAP00000030857	ENSANAP00000004197	Aftiphilin.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.664
AFTPH	AP1M2	ENSANAP00000030857	ENSANAP00000013532	Aftiphilin.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.664
AFTPH	AP2S1	ENSANAP00000030857	ENSANAP00000013752	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.402
AFTPH	AP3B1	ENSANAP00000030857	ENSANAP00000036409	Aftiphilin.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.408
AFTPH	ENSANAP00000005848	ENSANAP00000030857	ENSANAP00000005848	Aftiphilin.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.664
AFTPH	ENSANAP00000015320	ENSANAP00000030857	ENSANAP00000015320	Aftiphilin.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.584
AFTPH	SYNRG	ENSANAP00000030857	ENSANAP00000031657	Aftiphilin.	Synergin gamma.	0.660
AP1B1	AFTPH	ENSANAP00000002345	ENSANAP00000030857	AP complex subunit beta.	Aftiphilin.	0.420
AP1B1	AP1G1	ENSANAP00000002345	ENSANAP00000041879	AP complex subunit beta.	AP-1 complex subunit gamma.	0.995
AP1B1	AP1G2	ENSANAP00000002345	ENSANAP00000031284	AP complex subunit beta.	AP-1 complex subunit gamma.	0.985
AP1B1	AP1M1	ENSANAP00000002345	ENSANAP00000004197	AP complex subunit beta.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.977
AP1B1	AP1M2	ENSANAP00000002345	ENSANAP00000013532	AP complex subunit beta.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.977
AP1B1	AP2A1	ENSANAP00000002345	ENSANAP00000012805	AP complex subunit beta.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.958
AP1B1	AP2A2	ENSANAP00000002345	ENSANAP00000009874	AP complex subunit beta.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.944
AP1B1	AP2B1	ENSANAP00000002345	ENSANAP00000003540	AP complex subunit beta.	Uncharacterized protein.	0.447