STRINGSTRING
NTRK1 NTRK1 RAF1 RAF1 ENSANAP00000029410 ENSANAP00000029410 KDR KDR DDR1 DDR1 MUSK MUSK MAP3K20 MAP3K20 MAP3K11 MAP3K11 FGFR1 FGFR1 ENSANAP00000006266 ENSANAP00000006266 LYN LYN IRAK4 IRAK4 MAP3K13 MAP3K13 MAP3K12 MAP3K12 ACVR1C ACVR1C GUCY2F GUCY2F TESK1 TESK1 RYK RYK LIMK2 LIMK2 TNNI3K TNNI3K JAK3 JAK3 ILK ILK EPHB3 EPHB3 MAP3K9 MAP3K9 FGFR3 FGFR3 JAK2 JAK2 MAP3K7 MAP3K7 EPHB2 EPHB2 ITK ITK FLT1 FLT1 NPR1 NPR1 EPHB4 EPHB4 CSF1R CSF1R LTK LTK ACVR1B ACVR1B PTK7 PTK7 ANKK1 ANKK1 TNK1 TNK1 BMX BMX AXL AXL EPHB1 EPHB1 NEK6 NEK6 MLKL MLKL NRBP1 NRBP1 ROS1 ROS1 ABL1 ABL1 TEX14 TEX14 LMTK2 LMTK2 GUCY2C GUCY2C KIT KIT RIPK2 RIPK2 FLT4 FLT4 BRAF BRAF EPHB6 EPHB6 MAP3K21 MAP3K21 TXK TXK TEK TEK FGFR2 FGFR2 GUCY2D GUCY2D POMK POMK ERBB4 ERBB4 PTK2B PTK2B NTRK2 NTRK2 EPHA6 EPHA6 TNK2 TNK2 EPHA4 EPHA4 ARAF ARAF LCK LCK YES1 YES1 INSRR INSRR ALK ALK MERTK MERTK NTRK3 NTRK3 EPHA10 EPHA10 BTK BTK PTK2 PTK2 TEC TEC FRK FRK MATK MATK PDGFRB PDGFRB TESK2 TESK2 EPHA1 EPHA1 LMTK3 LMTK3 JAK1 JAK1 LIMK1 LIMK1 TYK2 TYK2 VRK3 VRK3 FES FES IGF1R IGF1R HCK HCK ACVR1 ACVR1 TYRO3 TYRO3 EPHA2 EPHA2 MAP3K10 MAP3K10 ABL2 ABL2 FYN FYN FGR FGR AATK AATK RIPK1 RIPK1 STYK1 STYK1 SRC SRC RIPK3 RIPK3 SRMS SRMS DSTYK DSTYK ACVRL1 ACVRL1 MST1R MST1R TGFBR2 TGFBR2 ENSANAP00000017314 ENSANAP00000017314 EPHA5 EPHA5 EPHA7 EPHA7 ERBB3 ERBB3 ROR1 ROR1 NEK7 NEK7 KSR2 KSR2 FLT3 FLT3 ZAP70 ZAP70 ERBB2 ERBB2 BLK BLK ROR2 ROR2 PTK6 PTK6 NPR2 NPR2 SCYL3 SCYL3 KSR1 KSR1 PDGFRA PDGFRA BMPR1B BMPR1B FER FER CSK CSK SYK SYK MET MET BMPR1A BMPR1A TIE1 TIE1 DDR2 DDR2 FGFR4 FGFR4 INSR INSR LOC105730226 LOC105730226
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NTRK1Tyrosine-protein kinase receptor. (796 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
ENSANAP00000029410Protein kinase domain-containing protein. (959 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (913 aa)
MUSKMuscle associated receptor tyrosine kinase. (866 aa)
MAP3K20Protein kinase domain-containing protein. (461 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
FGFR1Fibroblast growth factor receptor 1. (962 aa)
ENSANAP00000006266Non-specific serine/threonine protein kinase. (483 aa)
LYNLYN proto-oncogene, Src family tyrosine kinase. (498 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (965 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
GUCY2FGuanylate cyclase. (1108 aa)
TESK1Testis associated actin remodelling kinase 1. (544 aa)
RYKReceptor like tyrosine kinase. (599 aa)
LIMK2LIM domain kinase 2. (638 aa)
TNNI3KUncharacterized protein. (835 aa)
JAK3Tyrosine-protein kinase. (1119 aa)
ILKIntegrin linked kinase. (452 aa)
EPHB3EPH receptor B3. (1000 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (1103 aa)
FGFR3Fibroblast growth factor receptor. (798 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
EPHB2EPH receptor B2. (1114 aa)
ITKTyrosine-protein kinase. (620 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
NPR1Guanylate cyclase. (1061 aa)
EPHB4EPH receptor B4. (876 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (959 aa)
LTKTyrosine-protein kinase receptor. (863 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (545 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1080 aa)
ANKK1Ankyrin repeat and kinase domain containing 1. (765 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (666 aa)
BMXTyrosine-protein kinase. (679 aa)
AXLAXL receptor tyrosine kinase. (869 aa)
EPHB1EPH receptor B1. (967 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (326 aa)
MLKLMixed lineage kinase domain like pseudokinase. (471 aa)
NRBP1Nuclear receptor binding protein 1. (543 aa)
ROS1Tyrosine-protein kinase receptor. (2259 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1366 aa)
LMTK2Lemur tyrosine kinase 2. (1503 aa)
GUCY2CGuanylate cyclase. (1074 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (787 aa)
EPHB6EPH receptor B6. (1032 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase 21. (992 aa)
TXKTyrosine-protein kinase. (527 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
GUCY2DGuanylate cyclase. (1103 aa)
POMKProtein O-mannose kinase. (350 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
EPHA6EPH receptor A6. (1130 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1087 aa)
EPHA4EPH receptor A4. (986 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (618 aa)
LCKTyrosine-protein kinase Lck; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T- cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen- bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein [...] (541 aa)
YES1Tyrosine-protein kinase. (464 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
ALKTyrosine-protein kinase receptor. (1196 aa)
MERTKMER proto-oncogene, tyrosine kinase. (957 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
EPHA10EPH receptor A10. (897 aa)
BTKTyrosine-protein kinase. (659 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1077 aa)
TECTyrosine-protein kinase. (635 aa)
FRKTyrosine-protein kinase. (505 aa)
MATKTyrosine-protein kinase. (508 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1110 aa)
TESK2Testis associated actin remodelling kinase 2. (554 aa)
EPHA1EPH receptor A1. (969 aa)
LMTK3Lemur tyrosine kinase 3. (1405 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
LIMK1LIM domain kinase 1. (593 aa)
TYK2Tyrosine-protein kinase. (1226 aa)
VRK3VRK serine/threonine kinase 3. (424 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (808 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
HCKTyrosine-protein kinase. (505 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
EPHA2EPH receptor A2. (978 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (952 aa)
ABL2Tyrosine-protein kinase. (1103 aa)
FYNTyrosine-protein kinase. (537 aa)
FGRTyrosine-protein kinase. (514 aa)
AATKApoptosis associated tyrosine kinase. (1363 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
STYK1Serine/threonine/tyrosine kinase 1. (440 aa)
SRCTyrosine-protein kinase. (542 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (494 aa)
SRMSTyrosine-protein kinase. (482 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (929 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
MST1RMacrophage stimulating 1 receptor. (1399 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
ENSANAP00000017314Protein kinase domain-containing protein. (167 aa)
EPHA5EPH receptor A5. (1038 aa)
EPHA7EPH receptor A7. (998 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1359 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (303 aa)
KSR2Kinase suppressor of ras 2. (919 aa)
FLT3Fms related tyrosine kinase 3. (918 aa)
ZAP70Tyrosine-protein kinase. (605 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
BLKTyrosine-protein kinase. (500 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (899 aa)
PTK6Tyrosine-protein kinase. (451 aa)
NPR2Guanylate cyclase. (1048 aa)
SCYL3SCY1 like pseudokinase 3. (741 aa)
KSR1Kinase suppressor of ras 1. (858 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
CSKTyrosine-protein kinase. (450 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1391 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1144 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (879 aa)
FGFR4Fibroblast growth factor receptor. (691 aa)
INSRTyrosine-protein kinase receptor. (1302 aa)
LOC105730226Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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