STRINGSTRING
JAK1 JAK1 TYK2 TYK2 SOCS3 SOCS3 IL6 IL6 IL6ST IL6ST JAK2 JAK2 IL6R IL6R PTPN11 PTPN11 STAT1 STAT1 CBL CBL STAT3 STAT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAK1Tyrosine-protein kinase. (1153 aa)
TYK2Tyrosine-protein kinase. (1226 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
IL6Interleukin 6. (213 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
IL6RInterleukin 6 receptor. (378 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
STAT1Signal transducer and activator of transcription. (781 aa)
CBLCbl proto-oncogene. (908 aa)
STAT3Signal transducer and activator of transcription. (805 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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