STRINGSTRING
S100A9 S100A9 LY96 LY96 RPS6KA1 RPS6KA1 TAB2 TAB2 RELCH RELCH ENSANAP00000001198 ENSANAP00000001198 ENSANAP00000001338 ENSANAP00000001338 CREB5 CREB5 TAB3 TAB3 NLRC5 NLRC5 CD36 CD36 DUSP7 DUSP7 LOC105706260 LOC105706260 S100B S100B ENSANAP00000003669 ENSANAP00000003669 NLRP9 NLRP9 LOC105719658 LOC105719658 MAPK10 MAPK10 MAPK8 MAPK8 SKP1 SKP1 S100A8 S100A8 MAP3K8 MAP3K8 MAP2K6 MAP2K6 IRAK4 IRAK4 LOC105720202 LOC105720202 LRRC34 LRRC34 LOC105720203 LOC105720203 APP APP DUSP4 DUSP4 TIRAP TIRAP ENSANAP00000006464 ENSANAP00000006464 LRRC45 LRRC45 MAP3K20 MAP3K20 LOC105706650 LOC105706650 NKIRAS1 NKIRAS1 TONSL TONSL ENSANAP00000009508 ENSANAP00000009508 PELI2 PELI2 N4BP1 N4BP1 MEF2A MEF2A MAP2K1 MAP2K1 VWC2 VWC2 KHNYN KHNYN MYD88 MYD88 ENSANAP00000011604 ENSANAP00000011604 LOC110567995 LOC110567995 ENSANAP00000012193 ENSANAP00000012193 FOSL2 FOSL2 RPS6KA5 RPS6KA5 MAPK9 MAPK9 MAPK7 MAPK7 ENSANAP00000013693 ENSANAP00000013693 ELK1 ELK1 USP14 USP14 LOC105721341 LOC105721341 MAPK1 MAPK1 IRAK3 IRAK3 PPP4R1 PPP4R1 CREB1 CREB1 S100A12 S100A12 TLR4 TLR4 MAPKAPK2 MAPKAPK2 RPS6KA3 RPS6KA3 MAP3K7 MAP3K7 LRRC71 LRRC71 FNBP4 FNBP4 MAPK15 MAPK15 TRAF6 TRAF6 MAP3K1 MAP3K1 SIGIRR SIGIRR CUL1 CUL1 CASP8 CASP8 MAP2K3 MAP2K3 NKIRAS2 NKIRAS2 FOS FOS PELI1 PELI1 FGG FGG RIPK2 RIPK2 NFKBIA NFKBIA NLRP13 NLRP13 LRRC74A LRRC74A IRAK1 IRAK1 IKBKB IKBKB LOC110568879 LOC110568879 LOC105732229 LOC105732229 LOC105713378 LOC105713378 LOC105731662 LOC105731662 SOCS1 SOCS1 ALPK1 ALPK1 PPP2R1A PPP2R1A CCDC71L CCDC71L TLR6 TLR6 IRAK2 IRAK2 TAB1 TAB1 LRRC31 LRRC31 IKBKG IKBKG NFKBIB NFKBIB NOD1 NOD1 LRRC14 LRRC14 ATF7 ATF7 PELI3 PELI3 LOC105727559 LOC105727559 TNIP2 TNIP2 MAP2K7 MAP2K7 FGB FGB ENSANAP00000031356 ENSANAP00000031356 AGER AGER ATF1 ATF1 NFKB1 NFKB1 HMGB1 HMGB1 TRAF2 TRAF2 CD14 CD14 MAPK11 MAPK11 ENSANAP00000035706 ENSANAP00000035706 ENSANAP00000036022 ENSANAP00000036022 BTRC BTRC BTK BTK RELA RELA PPP2R1B PPP2R1B S100A1 S100A1 PPP2CB PPP2CB MAP2K4 MAP2K4 NLRX1 NLRX1 RPS6KA2 RPS6KA2 VRK3 VRK3 FBXW11 FBXW11 PPP2R5D PPP2R5D CREM CREM UBE2N UBE2N ENSANAP00000039113 ENSANAP00000039113 ENSANAP00000039594 ENSANAP00000039594 MAPKAPK3 MAPKAPK3 UBA52 UBA52 ATF2 ATF2 MEF2C MEF2C MAPK3 MAPK3 ECSIT ECSIT DUSP6 DUSP6 PPP2CA PPP2CA NLRP6 NLRP6 MAPK14 MAPK14 DUSP3 DUSP3 CHUK CHUK NFKB2 NFKB2 RPS27A RPS27A ENSANAP00000041846 ENSANAP00000041846 PPP4R4 PPP4R4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
S100A9Protein S100; Belongs to the S-100 family. (131 aa)
LY96Lymphocyte antigen 96. (160 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
ENSANAP00000001198Uncharacterized protein; Belongs to the SKP1 family. (158 aa)
ENSANAP00000001338Uncharacterized protein. (192 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
NLRC5NLR family CARD domain containing 5. (1815 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
LOC105706260Ubiquitin-like domain-containing protein. (154 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
ENSANAP00000003669Uncharacterized protein. (190 aa)
NLRP9NLR family pyrin domain containing 9. (934 aa)
LOC105719658Ubiquitin-like domain-containing protein. (156 aa)
MAPK10Mitogen-activated protein kinase. (533 aa)
MAPK8Mitogen-activated protein kinase. (387 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (451 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
LOC105720202Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (142 aa)
LRRC34Leucine rich repeat containing 34. (464 aa)
LOC105720203Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa)
APPAmyloid beta precursor protein. (741 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
ENSANAP00000006464UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
LRRC45Leucine rich repeat containing 45. (674 aa)
MAP3K20Protein kinase domain-containing protein. (461 aa)
LOC105706650Uncharacterized protein. (190 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
TONSLTonsoku like, DNA repair protein. (1371 aa)
ENSANAP00000009508Fib_alpha domain-containing protein. (287 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
N4BP1NEDD4 binding protein 1. (810 aa)
MEF2AMyocyte enhancer factor 2A. (506 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
KHNYNKH and NYN domain containing. (642 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
ENSANAP00000011604SER_THR_PHOSPHATASE domain-containing protein. (251 aa)
LOC110567995SER_THR_PHOSPHATASE domain-containing protein. (265 aa)
ENSANAP00000012193UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
MAPK9Mitogen-activated protein kinase 9. (442 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
ENSANAP00000013693Uncharacterized protein. (110 aa)
ELK1ETS transcription factor ELK1. (428 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa)
LOC105721341Uncharacterized protein. (397 aa)
MAPK1Mitogen-activated protein kinase. (376 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (589 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (951 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (80 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (392 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LRRC71Leucine rich repeat containing 71. (552 aa)
FNBP4Formin binding protein 4. (1020 aa)
MAPK15Protein kinase domain-containing protein. (246 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1508 aa)
SIGIRRSingle Ig and TIR domain containing. (488 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (525 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (392 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (239 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
FGGFibrinogen gamma chain. (453 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
NFKBIANFKB inhibitor alpha. (310 aa)
NLRP13NLR family pyrin domain containing 13. (985 aa)
LRRC74ALeucine rich repeat containing 74A. (487 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (711 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
LOC110568879UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
LOC105732229Ubiquitin-like domain-containing protein. (77 aa)
LOC105713378Ubiquitin-like domain-containing protein. (77 aa)
LOC105731662Ubiquitin conjugating enzyme E2 V1. (147 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
ALPK1Alpha kinase 1. (1262 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
CCDC71LUncharacterized protein. (253 aa)
TLR6Toll-like receptor. (766 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (605 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (505 aa)
LRRC31Leucine rich repeat containing 31. (590 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
LOC105727559Uncharacterized protein. (958 aa)
TNIP2TNFAIP3 interacting protein 2. (424 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (436 aa)
FGBFibrinogen beta chain. (488 aa)
ENSANAP00000031356Uncharacterized protein; Belongs to the SKP1 family. (154 aa)
AGERAdvanced glycosylation end-product specific receptor. (419 aa)
ATF1Activating transcription factor 1. (270 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
HMGB1High mobility group box 1. (215 aa)
TRAF2TNF receptor-associated factor. (493 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
ENSANAP00000035706Ubiquitin-like domain-containing protein. (101 aa)
ENSANAP00000036022Uncharacterized protein. (113 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (606 aa)
BTKTyrosine-protein kinase. (659 aa)
RELARELA proto-oncogene, NF-kB subunit. (540 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (749 aa)
S100A1Protein S100; Belongs to the S-100 family. (147 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (375 aa)
NLRX1NLR family member X1. (975 aa)
RPS6KA2Ribosomal protein S6 kinase. (756 aa)
VRK3VRK serine/threonine kinase 3. (424 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (600 aa)
CREMcAMP responsive element modulator. (332 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSANAP00000039113UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (113 aa)
ENSANAP00000039594SER_THR_PHOSPHATASE domain-containing protein. (268 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ATF2Activating transcription factor 2. (287 aa)
MEF2CMyocyte enhancer factor 2C. (490 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
ECSITECSIT signalling integrator. (430 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
PPP2CASerine/threonine-protein phosphatase. (219 aa)
NLRP6NLR family pyrin domain containing 6. (883 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSANAP00000041846Ubiquitin-like domain-containing protein. (144 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (873 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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