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NCEH1 NCEH1 MYLIP MYLIP ANGPTL3 ANGPTL3 LOC105706260 LOC105706260 PDIA2 PDIA2 AP2B1 AP2B1 LOC105719658 LOC105719658 ENSANAP00000005262 ENSANAP00000005262 LIPG LIPG HDLBP HDLBP VLDLR VLDLR GPIHBP1 GPIHBP1 LCAT LCAT MTTP MTTP LOC105710091 LOC105710091 LMF2 LMF2 FGF21 FGF21 MBTPS2 MBTPS2 AP2A2 AP2A2 LOC105716460 LOC105716460 A2ML1 A2ML1 LDLRAP1 LDLRAP1 CETP CETP LOC105732456 LOC105732456 PRKACA PRKACA NPC1 NPC1 PCSK9 PCSK9 CIDEC CIDEC AP2A1 AP2A1 PCSK4 PCSK4 SOAT2 SOAT2 PRKACB PRKACB AP2S1 AP2S1 PLEKHD1 PLEKHD1 ENSANAP00000014288 ENSANAP00000014288 ZDHHC19 ZDHHC19 ABCG1 ABCG1 LPL LPL APOF APOF AMN AMN PCSK6 PCSK6 FURIN FURIN APOC2 APOC2 ENSANAP00000019172 ENSANAP00000019172 APOC4 APOC4 SOAT1 SOAT1 PLTP PLTP APOE APOE CREB3L3 CREB3L3 ALB ALB P4HB P4HB ENSANAP00000023918 ENSANAP00000023918 PTCHD4 PTCHD4 PTCHD3 PTCHD3 CDCP2 CDCP2 PLG PLG SAR1A SAR1A ENSANAP00000025391 ENSANAP00000025391 LMF1 LMF1 APOA5 APOA5 LOC105731947 LOC105731947 LOC105732229 LOC105732229 LOC105713378 LOC105713378 SMPDL3A SMPDL3A CUBN CUBN APOA2 APOA2 APOB APOB ZDHHC8 ZDHHC8 A2M A2M LOC105718653 LOC105718653 LIPC LIPC ENSANAP00000029929 ENSANAP00000029929 SAR1B SAR1B AADACL3 AADACL3 LOC105732592 LOC105732592 APOC3 APOC3 ABCA1 ABCA1 ANGPTL4 ANGPTL4 APOA4 APOA4 ILDR2 ILDR2 APOA1 APOA1 SCARB1 SCARB1 NR1H2 NR1H2 NPC2 NPC2 BMP1 BMP1 LSR LSR AP2M1 AP2M1 ENSANAP00000035706 ENSANAP00000035706 ENSANAP00000036022 ENSANAP00000036022 PTCHD1 PTCHD1 LDLR LDLR APOBR APOBR CLHC1 CLHC1 UBA52 UBA52 MBTPS1 MBTPS1 CLTC CLTC CLTA CLTA LOC105725485 LOC105725485 NR1H3 NR1H3 RPS27A RPS27A ENSANAP00000041846 ENSANAP00000041846 LIPA LIPA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCEH1Neutral cholesterol ester hydrolase 1. (444 aa)
MYLIPMyosin regulatory light chain interacting protein. (445 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
LOC105706260Ubiquitin-like domain-containing protein. (154 aa)
PDIA2Protein disulfide isomerase family A member 2. (526 aa)
AP2B1Uncharacterized protein. (928 aa)
LOC105719658Ubiquitin-like domain-containing protein. (156 aa)
ENSANAP00000005262Uncharacterized protein; Belongs to the protein kinase superfamily. (337 aa)
LIPGLipase G, endothelial type. (500 aa)
HDLBPHigh density lipoprotein binding protein. (1268 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (180 aa)
LCATLecithin-cholesterol acyltransferase. (442 aa)
MTTPMicrosomal triglyceride transfer protein. (870 aa)
LOC105710091Uncharacterized protein. (738 aa)
LMF2Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (707 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (507 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
LOC105716460Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family. (171 aa)
A2ML1Alpha-2-macroglobulin like 1. (1269 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
CETPCholesteryl ester transfer protein. (521 aa)
LOC105732456Uncharacterized protein. (983 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (690 aa)
CIDECCell death inducing DFFA like effector c. (248 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (736 aa)
SOAT2O-acyltransferase. (526 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (358 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
PLEKHD1Pleckstrin homology and coiled-coil domain containing D1. (466 aa)
ENSANAP00000014288Uncharacterized protein. (331 aa)
ZDHHC19Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (305 aa)
ABCG1ATP binding cassette subfamily G member 1. (603 aa)
LPLLipoprotein lipase. (453 aa)
APOFApolipoprotein F. (326 aa)
AMNAmnion associated transmembrane protein. (452 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (933 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (861 aa)
APOC2Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (101 aa)
ENSANAP00000019172Uncharacterized protein. (3145 aa)
APOC4Apolipoprotein C-IV; May participate in lipoprotein metabolism; Belongs to the apolipoprotein C4 family. (127 aa)
SOAT1O-acyltransferase. (519 aa)
PLTPPhospholipid transfer protein. (548 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (281 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (501 aa)
ALBAlbumin. (608 aa)
P4HBUncharacterized protein; Belongs to the protein disulfide isomerase family. (529 aa)
ENSANAP00000023918Uncharacterized protein; Belongs to the protein kinase superfamily. (318 aa)
PTCHD4Patched domain containing 4. (846 aa)
PTCHD3Patched domain containing 3. (675 aa)
CDCP2CUB domain containing protein 2. (540 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
ENSANAP00000025391Uncharacterized protein. (99 aa)
LMF1Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (541 aa)
APOA5Apolipoprotein A5. (366 aa)
LOC105731947Uncharacterized protein. (348 aa)
LOC105732229Ubiquitin-like domain-containing protein. (77 aa)
LOC105713378Ubiquitin-like domain-containing protein. (77 aa)
SMPDL3AAcid sphingomyelinase-like phosphodiesterase. (453 aa)
CUBNCubilin. (3655 aa)
APOA2Apolipoprotein A2. (132 aa)
APOBApolipoprotein B. (3824 aa)
ZDHHC8Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (750 aa)
A2MAlpha-2-macroglobulin. (1475 aa)
LOC105718653Uncharacterized protein; Belongs to the peptidase S8 family. (913 aa)
LIPCLipase C, hepatic type. (499 aa)
ENSANAP00000029929Uncharacterized protein. (890 aa)
SAR1BSecretion associated Ras related GTPase 1B. (165 aa)
AADACL3Arylacetamide deacetylase like 3. (406 aa)
LOC105732592Uncharacterized protein. (1275 aa)
APOC3Apolipoprotein C3. (117 aa)
ABCA1ATP binding cassette subfamily A member 1. (2220 aa)
ANGPTL4Angiopoietin like 4. (373 aa)
APOA4Apolipoprotein A4. (396 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (637 aa)
APOA1Apolipoprotein A1. (265 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (551 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (459 aa)
NPC2NPC intracellular cholesterol transporter 2. (203 aa)
BMP1Metalloendopeptidase. (986 aa)
LSRLipolysis stimulated lipoprotein receptor. (603 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
ENSANAP00000035706Ubiquitin-like domain-containing protein. (101 aa)
ENSANAP00000036022Uncharacterized protein. (113 aa)
PTCHD1Patched domain containing 1. (888 aa)
LDLRLow density lipoprotein receptor. (786 aa)
APOBRApolipoprotein B receptor. (1056 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (587 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
LOC105725485AP complex subunit beta. (903 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (452 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSANAP00000041846Ubiquitin-like domain-containing protein. (144 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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