STRINGSTRING
TTC6 TTC6 TNFRSF10A TNFRSF10A BIRC7 BIRC7 IRF1 IRF1 BIRC3 BIRC3 TP63 TP63 ENSANAP00000036022 ENSANAP00000036022 GSDME GSDME ENSANAP00000035706 ENSANAP00000035706 NPVF NPVF PDCD6IP PDCD6IP HMGB1 HMGB1 TRAF2 TRAF2 ENSANAP00000003669 ENSANAP00000003669 ENSANAP00000003726 ENSANAP00000003726 GSDMD GSDMD CHMP7 CHMP7 LOC105719658 LOC105719658 FLOT1 FLOT1 LOC105709072 LOC105709072 LOC105706650 LOC105706650 ELANE ELANE OGT OGT CHMP4B CHMP4B CHMP2B CHMP2B FLOT2 FLOT2 TNFRSF10D TNFRSF10D CFLAR CFLAR CDC37 CDC37 FASLG FASLG CASP3 CASP3 CHMP4C CHMP4C LOC105721341 LOC105721341 XIAP XIAP LOC105709175 LOC105709175 BAK1 BAK1 LOC105728613 LOC105728613 BAX BAX CHMP2A CHMP2A CHMP6 CHMP6 ENSANAP00000019048 ENSANAP00000019048 STUB1 STUB1 CASP4 CASP4 ITCH ITCH MDP1 MDP1 CARD18 CARD18 ENSANAP00000021346 ENSANAP00000021346 IL1A IL1A IL1B IL1B ENSANAP00000000642 ENSANAP00000000642 ENSANAP00000000902 ENSANAP00000000902 ENSANAP00000001338 ENSANAP00000001338 ENSANAP00000002308 ENSANAP00000002308 LOC105706260 LOC105706260 LOC110568101 LOC110568101 CASP8 CASP8 MLKL MLKL PELI1 PELI1 ENSANAP00000003370 ENSANAP00000003370 IRF2 IRF2 ENSANAP00000003515 ENSANAP00000003515 SDCBP SDCBP TNFSF10 TNFSF10 ENSANAP00000025464 ENSANAP00000025464 FADD FADD LOC105732229 LOC105732229 LOC105713378 LOC105713378 LOC105732154 LOC105732154 LOC105712346 LOC105712346 IL18 IL18 TNFRSF10B TNFRSF10B PRKN PRKN LOC105719329 LOC105719329 GZMB GZMB RIPK1 RIPK1 LOC105731242 LOC105731242 RIPK3 RIPK3 ENSANAP00000031715 ENSANAP00000031715 ENSANAP00000041846 ENSANAP00000041846 RPS27A RPS27A FAS FAS TRADD TRADD UBA52 UBA52 BIRC2 BIRC2 HSP90AA1 HSP90AA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTC6TPR_REGION domain-containing protein. (1882 aa)
TNFRSF10ATNF receptor superfamily member 10a. (431 aa)
BIRC7Baculoviral IAP repeat containing 7. (290 aa)
IRF1Interferon regulatory factor. (325 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ENSANAP00000036022Uncharacterized protein. (113 aa)
GSDMEGasdermin E. (496 aa)
ENSANAP00000035706Ubiquitin-like domain-containing protein. (101 aa)
NPVFNeuropeptide VF precursor. (196 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (868 aa)
HMGB1High mobility group box 1. (215 aa)
TRAF2TNF receptor-associated factor. (493 aa)
ENSANAP00000003669Uncharacterized protein. (190 aa)
ENSANAP00000003726Uncharacterized protein. (212 aa)
GSDMDGasdermin D. (481 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
LOC105719658Ubiquitin-like domain-containing protein. (156 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
LOC105709072HATPase_c domain-containing protein. (329 aa)
LOC105706650Uncharacterized protein. (190 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
CHMP2BCharged multivesicular body protein 2B. (215 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (483 aa)
TNFRSF10DTNF receptor superfamily member 10d. (383 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
CDC37Cell division cycle 37. (378 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (279 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
LOC105721341Uncharacterized protein. (397 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
LOC105709175Caspase recruitment domain family member 17. (110 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
LOC105728613UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
BAXBCL2 associated X, apoptosis regulator. (193 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
CHMP6Charged multivesicular body protein 6. (214 aa)
ENSANAP00000019048Uncharacterized protein. (213 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (377 aa)
ITCHE3 ubiquitin-protein ligase. (860 aa)
MDP1Magnesium dependent phosphatase 1. (167 aa)
CARD18Caspase recruitment domain family member 18. (91 aa)
ENSANAP00000021346CARD domain-containing protein. (110 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (231 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
ENSANAP00000000642Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSANAP00000000902Uncharacterized protein. (221 aa)
ENSANAP00000001338Uncharacterized protein. (192 aa)
ENSANAP00000002308Uncharacterized protein. (221 aa)
LOC105706260Ubiquitin-like domain-containing protein. (154 aa)
LOC110568101Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (525 aa)
MLKLMixed lineage kinase domain like pseudokinase. (471 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
ENSANAP00000003370Uncharacterized protein. (119 aa)
IRF2Interferon regulatory factor. (349 aa)
ENSANAP00000003515HATPase_c domain-containing protein. (532 aa)
SDCBPSyndecan binding protein. (316 aa)
TNFSF10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (373 aa)
ENSANAP00000025464CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (249 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (207 aa)
LOC105732229Ubiquitin-like domain-containing protein. (77 aa)
LOC105713378Ubiquitin-like domain-containing protein. (77 aa)
LOC105732154Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC105712346Uncharacterized protein. (213 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
TNFRSF10BTNF receptor superfamily member 10b. (385 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
LOC105719329Uncharacterized protein; Belongs to the peptidase C14A family. (404 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (304 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
LOC105731242Uncharacterized protein. (221 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (494 aa)
ENSANAP00000031715Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
ENSANAP00000041846Ubiquitin-like domain-containing protein. (144 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FASFas cell surface death receptor. (329 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (790 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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