STRINGSTRING
MSH2 MSH2 EXO1 EXO1 POLD1 POLD1 RPA1 RPA1 LOC105723072 LOC105723072 LIG1 LIG1 MEIOB MEIOB POLD4 POLD4 PCNA PCNA PMS2 PMS2 POLD3 POLD3 MLH1 MLH1 POLD2 POLD2 MSH3 MSH3 RPA3 RPA3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (866 aa)
EXO1Exonuclease 1. (848 aa)
POLD1DNA polymerase delta 1, catalytic subunit. (1066 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
LOC105723072DNA_mis_repair domain-containing protein. (626 aa)
LIG1DNA ligase. (881 aa)
MEIOBMeiosis specific with OB-fold. (447 aa)
POLD4Uncharacterized protein. (107 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PMS2PMS1 homolog 2, mismatch repair system component. (862 aa)
POLD3DNA polymerase delta 3, accessory subunit. (466 aa)
MLH1DNA_mis_repair domain-containing protein. (757 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
MSH3MutS homolog 3. (879 aa)
RPA3Replication protein A3. (134 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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