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| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | ENSANAP00000008119 | Uncharacterized protein. (157 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | LOC105718467 | USP domain-containing protein; Belongs to the peptidase C19 family. (841 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1325 aa) |
| | NPEPL1 | Aminopeptidase like 1. (523 aa) |
| | USP22 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa) |
| | WDR20 | WD repeat domain 20. (612 aa) |
| | ADRM1 | RPN13_C domain-containing protein. (407 aa) |
| | KLHL18 | Kelch like family member 18. (430 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (624 aa) |
| | PSMB8 | Proteasome subunit beta 8. (250 aa) |
| | LOC105721445 | Uncharacterized protein. (244 aa) |
| | PSME3 | Proteasome activator subunit 3. (267 aa) |
| | USP26 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (915 aa) |
| | SKP2 | F-box domain-containing protein. (435 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (353 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (963 aa) |
| | USP28 | Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1117 aa) |
| | ENSANAP00000012253 | Proteasome endopeptidase complex. (205 aa) |
| | LOC105723059 | Uncharacterized protein. (220 aa) |
| | USP33 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (922 aa) |
| | USP5 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa) |
| | PSMA1 | Proteasome subunit alpha type. (283 aa) |
| | PSME1 | Proteasome activator subunit 1. (250 aa) |
| | PSMD12 | PCI domain-containing protein. (456 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (463 aa) |
| | ENSANAP00000013599 | Uncharacterized protein. (57 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | USP10 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa) |
| | ENSANAP00000014529 | USP7_C2 domain-containing protein. (291 aa) |
| | USP16 | Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (826 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa) |
| | ENSANAP00000014796 | PX domain-containing protein. (143 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | ADRB2 | Adrenoceptor beta 2. (426 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (311 aa) |
| | USP48 | Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (1052 aa) |
| | ENSANAP00000015747 | Uncharacterized protein. (416 aa) |
| | ENSANAP00000015998 | Uncharacterized protein. (120 aa) |
| | ENSANAP00000016151 | Uncharacterized protein. (202 aa) |
| | UBFD1 | Ubiquitin family domain containing 1. (364 aa) |
| | H2BW1 | H2B histone family member W, testis specific; Belongs to the histone H2B family. (181 aa) |
| | USP13 | Ubiquitin carboxyl-terminal hydrolase. (829 aa) |
| | LAP3 | Leucine aminopeptidase 3. (519 aa) |
| | ENSANAP00000017252 | Uncharacterized protein. (107 aa) |
| | KAT2A | Lysine acetyltransferase 2A. (844 aa) |
| | H2BC18 | Histone H2B; Belongs to the histone H2B family. (134 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | USP25 | Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1125 aa) |
| | LOC105711962 | MDM2 proto-oncogene. (418 aa) |
| | LOC105713290 | AAA domain-containing protein; Belongs to the AAA ATPase family. (352 aa) |
| | USP4 | Ubiquitin specific peptidase 4; Belongs to the peptidase C19 family. (963 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (312 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa) |
| | ENSANAP00000020209 | USP domain-containing protein. (402 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (489 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1025 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa) |
| | USP34 | Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3458 aa) |
| | ATXN7L1 | Ataxin 7 like 1. (965 aa) |
| | SNX3 | Sorting nexin 3. (162 aa) |
| | RNF146 | Uncharacterized protein. (359 aa) |
| | KIAA2012 | KIAA2012. (1179 aa) |
| | CCNA2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (432 aa) |
| | CDC25A | Cell division cycle 25A. (510 aa) |
| | ENSANAP00000024339 | Uncharacterized protein. (168 aa) |
| | RHOT1 | Ras homolog family member T1. (752 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (444 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | USP36 | Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1126 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (352 aa) |
| | ENSANAP00000024867 | Rab-GAP TBC domain-containing protein. (81 aa) |
| | ENSANAP00000024924 | Ubiquitinyl hydrolase 1. (495 aa) |
| | ENSANAP00000025026 | Uncharacterized protein. (218 aa) |
| | AXIN2 | Axin 2. (843 aa) |
| | DMWD | DM1 locus, WD repeat containing. (668 aa) |
| | ENSANAP00000025528 | Uncharacterized protein. (225 aa) |
| | LOC105709634 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (337 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | NFKBIA | NFKB inhibitor alpha. (310 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | ENSANAP00000026489 | Uncharacterized protein. (270 aa) |
| | LOC105732229 | Ubiquitin-like domain-containing protein. (77 aa) |
| | GATA3 | GATA binding protein 3. (409 aa) |
| | LOC105713378 | Ubiquitin-like domain-containing protein. (77 aa) |
| | TADA3 | Transcriptional adaptor 3. (397 aa) |
| | LOC105731676 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (234 aa) |
| | USP51 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (710 aa) |
| | LOC105719962 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | TADA2B | Transcriptional adapter. (420 aa) |
| | LOC105728210 | RPN13_C domain-containing protein. (407 aa) |
| | LOC105726406 | Histone H2B type 1-H. (126 aa) |
| | UFD1 | Ubiquitin recognition factor in ER associated degradation 1. (307 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | LOC105726424 | Histone H2B type 1-H. (126 aa) |
| | H2AC12 | H2A clustered histone 12. (128 aa) |
| | LOC105731119 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa) |
| | NRDC | Nardilysin convertase. (1229 aa) |
| | DDX58 | DExD/H-box helicase 58. (855 aa) |
| | USP37 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (980 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3860 aa) |
| | FOXO4 | Forkhead box O4. (505 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (505 aa) |
| | USP12 | Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family. (374 aa) |
| | RNF13 | Ring finger protein 13. (381 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa) |
| | LOC105710430 | Uncharacterized protein. (345 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | SNX12 | Sorting nexin 12. (172 aa) |
| | RCE1 | Ras converting CAAX endopeptidase 1. (329 aa) |
| | USP11 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (968 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | AR | Androgen receptor. (887 aa) |
| | PSMB6 | Proteasome subunit beta. (281 aa) |
| | LOC105721511 | Uncharacterized protein; Belongs to the histone H2B family. (89 aa) |
| | USP44 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (712 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | ENSANAP00000031039 | Histone H2B; Belongs to the histone H2B family. (129 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | RNF123 | Ring finger protein 123. (1314 aa) |
| | ATXN7 | SCA7 domain-containing protein. (907 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (292 aa) |
| | ENSANAP00000031797 | Uncharacterized protein. (416 aa) |
| | TOMM20 | Translocase of outer mitochondrial membrane 20. (146 aa) |
| | LOC105713215 | Uncharacterized protein. (277 aa) |
| | USP42 | Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family. (1319 aa) |
| | PSMC6 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) |
| | ENSANAP00000032311 | AAA domain-containing protein; Belongs to the AAA ATPase family. (412 aa) |
| | USP20 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (915 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (244 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMD7 | MPN domain-containing protein. (324 aa) |
| | ENSANAP00000033417 | Uncharacterized protein. (338 aa) |
| | TRAF2 | TNF receptor-associated factor. (493 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (736 aa) |
| | SUDS3 | SDS3 homolog, SIN3A corepressor complex component. (328 aa) |
| | USP24 | Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2625 aa) |
| | LOC105707470 | F-box domain-containing protein. (414 aa) |
| | ENSANAP00000034137 | Uncharacterized protein. (369 aa) |
| | RNF167 | Ring finger protein 167. (352 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSANAP00000034576 | Uncharacterized protein. (186 aa) |
| | PSME2 | Uncharacterized protein. (254 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (287 aa) |
| | ENSANAP00000035706 | Ubiquitin-like domain-containing protein. (101 aa) |
| | ENSANAP00000036022 | Uncharacterized protein. (113 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (435 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | LOC105717376 | Uncharacterized protein. (273 aa) |
| | LOC105734258 | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (279 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | ZFYVE19 | Zinc finger FYVE-type containing 19. (462 aa) |
| | ENSANAP00000037220 | Uncharacterized protein. (221 aa) |
| | LOC105723668 | Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (612 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (293 aa) |
| | PSME4 | Proteasome activator subunit 4. (1840 aa) |
| | ARRB2 | Arrestin beta 2. (460 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | CDC20 | Cell division cycle 20. (519 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | BECN1 | Beclin 1. (453 aa) |
| | USP21 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (573 aa) |
| | LOC105709408 | RING-type domain-containing protein. (162 aa) |
| | ENSANAP00000041846 | Ubiquitin-like domain-containing protein. (144 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | USP3 | Ubiquitinyl hydrolase 1. (501 aa) |
| | LOC105706974 | USP domain-containing protein; Belongs to the peptidase C19 family. (473 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (606 aa) |
| | MAT2B | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (334 aa) |
| | ENSANAP00000041359 | Uncharacterized protein. (193 aa) |
| | USP8 | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1117 aa) |
| | LOC105730695 | Rab-GAP TBC domain-containing protein. (161 aa) |
| | TNKS2 | Poly [ADP-ribose] polymerase. (1178 aa) |
| | ATXN7L2 | Ataxin 7 like 2. (705 aa) |
| | LOC105713293 | Uncharacterized protein. (328 aa) |
| | USP46 | Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family. (366 aa) |
| | CLSPN | Claspin. (1353 aa) |
| | USP19 | Ubiquitin specific peptidase 19. (1421 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2576 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (454 aa) |
| | ARRB1 | Arrestin beta 1. (418 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | ENSANAP00000039203 | Uncharacterized protein. (102 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (492 aa) |
| | ENSANAP00000038876 | Uncharacterized protein. (266 aa) |
| | ENSANAP00000038840 | Uncharacterized protein. (221 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (290 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (507 aa) |
| | ENSANAP00000038542 | Proteasome subunit alpha type. (190 aa) |
| | LOC105709894 | Proteasome endopeptidase complex. (222 aa) |
| | LOC105721624 | ANK_REP_REGION domain-containing protein. (232 aa) |
| | H2AC20 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | STAM2 | Signal transducing adaptor molecule 2. (525 aa) |
| | H2BC15 | Histone H2B; Belongs to the histone H2B family. (170 aa) |
| | ENSANAP00000000124 | AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | RNF128 | Ring finger protein 128. (428 aa) |
| | LOC105726425 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC105726419 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | ENSANAP00000000667 | Proteasome endopeptidase complex. (261 aa) |
| | WDR48 | WD repeat domain 48. (677 aa) |
| | LOC105707274 | AAA domain-containing protein. (352 aa) |
| | H2AC6 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | WDR76 | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (622 aa) |
| | GPR52 | G protein-coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | PSMA7 | Proteasome subunit alpha type. (252 aa) |
| | H2AC7 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | UBLCP1 | Ubiquitin like domain containing CTD phosphatase 1. (318 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | ZNRF4 | Zinc and ring finger 4. (423 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (842 aa) |
| | LOC105728767 | Proteasome subunit alpha type. (263 aa) |
| | LOC105726420 | Histone H2A type 1. (130 aa) |
| | LOC105717768 | Proteasome subunit alpha type. (234 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | H2AC21 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | LOC105717114 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (210 aa) |
| | MTFP1 | Mitochondrial fission process 1. (166 aa) |
| | ENSANAP00000002683 | Uncharacterized protein. (204 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1226 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (267 aa) |
| | FKBP8 | Peptidylprolyl isomerase. (444 aa) |
| | USP27X | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (793 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | ENSANAP00000003122 | Uncharacterized protein. (207 aa) |
| | LOC105721506 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC105706260 | Ubiquitin-like domain-containing protein. (154 aa) |
| | ENSANAP00000003293 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (419 aa) |
| | H2BC8 | Histone H2B; Belongs to the histone H2B family. (130 aa) |
| | IL33 | Interleukin 33. (247 aa) |
| | LOC105726466 | Proteasome endopeptidase complex. (242 aa) |
| | LOC105719658 | Ubiquitin-like domain-containing protein. (156 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (378 aa) |
| | H2BC21 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC105721457 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | USP7 | Uncharacterized protein; Belongs to the peptidase C19 family. (1101 aa) |
| | PSMA6 | Proteasome subunit alpha type. (253 aa) |
| | H2BC5 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | CCP110 | Centriolar coiled-coil protein 110. (1012 aa) |
| | PSMD9 | Uncharacterized protein. (250 aa) |
| | USP30 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (534 aa) |
| | OTUB1 | Ubiquitin thioesterase. (280 aa) |
| | TOMM70 | Translocase of outer mitochondrial membrane 70. (608 aa) |
| | LOC105710021 | Ubiquitinyl hydrolase 1. (695 aa) |
| | PSMA8 | Proteasome subunit alpha type. (256 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | USP32 | Uncharacterized protein; Belongs to the peptidase C19 family. (1603 aa) |
| | CDC20B | Cell division cycle 20B. (519 aa) |
| | USP49 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (688 aa) |
| | ENSANAP00000006479 | F-box domain-containing protein. (371 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa) |
| | MAP3K20 | Protein kinase domain-containing protein. (461 aa) |
| | PTRH2 | Peptidyl-tRNA hydrolase 2. (180 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | LOC105719963 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | ENSANAP00000007597 | ANK_REP_REGION domain-containing protein. (190 aa) |
| | TOMM20L | Translocase of outer mitochondrial membrane 20 like. (151 aa) |
| | LOC105734262 | WD_REPEATS_REGION domain-containing protein. (550 aa) |
