24 items (Aotus nancymaae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RFC3	Replication factor C subunit 3. (356 aa)
	RFC5	Replication factor C subunit 5. (340 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	RPA3	Replication protein A3. (134 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	POLD1	DNA polymerase delta 1, catalytic subunit. (1066 aa)
	ENSANAP00000014871	Uncharacterized protein. (107 aa)
	LIG1	DNA ligase. (881 aa)
	RFC1	Replication factor C subunit 1. (1136 aa)
	PRIM1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (504 aa)
	PRIM2	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (507 aa)
	POLD3	DNA polymerase delta 3, accessory subunit. (466 aa)
	POLA2	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
	POLA1	DNA polymerase. (1475 aa)
	MEIOB	Meiosis specific with OB-fold. (447 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	POLD4	Uncharacterized protein. (107 aa)
	RFC4	Replication factor C subunit 4. (363 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	DNA2	DNA replication helicase/nuclease 2. (936 aa)
	ATAD5	ATPase family AAA domain containing 5. (1835 aa)

Your Current Organism:

Aotus nancymaae

NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	DNA2	ENSANAP00000042030	ENSANAP00000040319	ATPase family AAA domain containing 5.	DNA replication helicase/nuclease 2.	0.928
ATAD5	ENSANAP00000014871	ENSANAP00000042030	ENSANAP00000014871	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.961
ATAD5	FEN1	ENSANAP00000042030	ENSANAP00000003878	ATPase family AAA domain containing 5.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.954
ATAD5	LIG1	ENSANAP00000042030	ENSANAP00000015982	ATPase family AAA domain containing 5.	DNA ligase.	0.845
ATAD5	MEIOB	ENSANAP00000042030	ENSANAP00000032272	ATPase family AAA domain containing 5.	Meiosis specific with OB-fold.	0.800
ATAD5	PCNA	ENSANAP00000042030	ENSANAP00000040255	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.974
ATAD5	POLA1	ENSANAP00000042030	ENSANAP00000027767	ATPase family AAA domain containing 5.	DNA polymerase.	0.876
ATAD5	POLA2	ENSANAP00000042030	ENSANAP00000025941	ATPase family AAA domain containing 5.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.877
ATAD5	POLD1	ENSANAP00000042030	ENSANAP00000014467	ATPase family AAA domain containing 5.	DNA polymerase delta 1, catalytic subunit.	0.813
ATAD5	POLD2	ENSANAP00000042030	ENSANAP00000019787	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.672
ATAD5	PRIM1	ENSANAP00000042030	ENSANAP00000019739	ATPase family AAA domain containing 5.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.804
ATAD5	PRIM2	ENSANAP00000042030	ENSANAP00000021875	ATPase family AAA domain containing 5.	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	0.870
ATAD5	RFC1	ENSANAP00000042030	ENSANAP00000017228	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.730
ATAD5	RFC2	ENSANAP00000042030	ENSANAP00000013195	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.966
ATAD5	RFC3	ENSANAP00000042030	ENSANAP00000004817	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.987
ATAD5	RFC4	ENSANAP00000042030	ENSANAP00000033150	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.990
ATAD5	RFC5	ENSANAP00000042030	ENSANAP00000002939	ATPase family AAA domain containing 5.	Replication factor C subunit 5.	0.980
ATAD5	RPA1	ENSANAP00000042030	ENSANAP00000010977	ATPase family AAA domain containing 5.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.800
ATAD5	RPA3	ENSANAP00000042030	ENSANAP00000005953	ATPase family AAA domain containing 5.	Replication protein A3.	0.595
DNA2	ATAD5	ENSANAP00000040319	ENSANAP00000042030	DNA replication helicase/nuclease 2.	ATPase family AAA domain containing 5.	0.928