ATPase family AAA domain containing 5.

Cell division cycle 45.

ATPase family AAA domain containing 5.

DNA replication helicase/nuclease 2.

ATPase family AAA domain containing 5.

Uncharacterized protein.

ATPase family AAA domain containing 5.

Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]

ATPase family AAA domain containing 5.

DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.

ATPase family AAA domain containing 5.

DNA ligase.

ATPase family AAA domain containing 5.

DNA helicase; Belongs to the MCM family.

ATPase family AAA domain containing 5.

DNA helicase; Belongs to the MCM family.

ATPase family AAA domain containing 5.

DNA helicase; Belongs to the MCM family.

ATPase family AAA domain containing 5.

DNA helicase; Belongs to the MCM family.

ATPase family AAA domain containing 5.

DNA helicase; Belongs to the MCM family.

ATPase family AAA domain containing 5.

DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

ATPase family AAA domain containing 5.

Meiosis specific with OB-fold.

ATPase family AAA domain containing 5.

Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.

ATPase family AAA domain containing 5.

DNA polymerase.

ATPase family AAA domain containing 5.

DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.

ATPase family AAA domain containing 5.

DNA polymerase delta 1, catalytic subunit.

ATPase family AAA domain containing 5.

DNA polymerase delta 2, accessory subunit.

ATPase family AAA domain containing 5.

DNA primase; Belongs to the eukaryotic-type primase small subunit family.

ATPase family AAA domain containing 5.

DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.