STRINGSTRING
POLR2L POLR2L HDAC1 HDAC1 ZNRD1 ZNRD1 MTA1 MTA1 ERCC2 ERCC2 CBX3 CBX3 CD3EAP CD3EAP ENSANAP00000008309 ENSANAP00000008309 POLR2K POLR2K MBD2 MBD2 ENSANAP00000024880 ENSANAP00000024880 MTA3 MTA3 DMTF1 DMTF1 AIRE AIRE CHD3 CHD3 CAVIN1 CAVIN1 POLR1A POLR1A LOC105712089 LOC105712089 ENSANAP00000032176 ENSANAP00000032176 ENSANAP00000032143 ENSANAP00000032143 TBPL1 TBPL1 ENSANAP00000031039 ENSANAP00000031039 ENSANAP00000002458 ENSANAP00000002458 ENSANAP00000002499 ENSANAP00000002499 ENSANAP00000003064 ENSANAP00000003064 LOC105721506 LOC105721506 H2BC8 H2BC8 LOC105721512 LOC105721512 LOC105716903 LOC105716903 ENSANAP00000003960 ENSANAP00000003960 H2BC21 H2BC21 ENSANAP00000004003 ENSANAP00000004003 LOC105721457 LOC105721457 ENSANAP00000004261 ENSANAP00000004261 ENSANAP00000004291 ENSANAP00000004291 ENSANAP00000004318 ENSANAP00000004318 POLR2H POLR2H H2BC5 H2BC5 TAF1A TAF1A POLR2F POLR2F MNAT1 MNAT1 H2AZ2 H2AZ2 MTA2 MTA2 TAF1D TAF1D LOC105722322 LOC105722322 LOC105719961 LOC105719961 ENSANAP00000027055 ENSANAP00000027055 ENSANAP00000026983 ENSANAP00000026983 LOC105709928 LOC105709928 ERCC3 ERCC3 KAT2B KAT2B C11orf88 C11orf88 LOC105726422 LOC105726422 KAT2A KAT2A TWISTNB TWISTNB GTF2H4 GTF2H4 POLR1B POLR1B MBD3 MBD3 H2BW1 H2BW1 POLR1C POLR1C ENSANAP00000001222 ENSANAP00000001222 H2AJ H2AJ H2BC3 H2BC3 ENSANAP00000000978 ENSANAP00000000978 UBN2 UBN2 H2AC6 H2AC6 LOC105719964 LOC105719964 LOC105713881 LOC105713881 GCNA GCNA LOC105726425 LOC105726425 ENSANAP00000000291 ENSANAP00000000291 CHD5 CHD5 H2BC15 H2BC15 LOC105726417 LOC105726417 LOC110567286 LOC110567286 LOC105726427 LOC105726427 LOC105726426 LOC105726426 LOC105726406 LOC105726406 GTF2H5 GTF2H5 LOC105726424 LOC105726424 LOC105721499 LOC105721499 LOC105721488 LOC105721488 LOC105728434 LOC105728434 H2AC7 H2AC7 H2BU1 H2BU1 H2AC20 H2AC20 ENSANAP00000027620 ENSANAP00000027620 TAF1B TAF1B LOC105726785 LOC105726785 LOC105731119 LOC105731119 ENSANAP00000029155 ENSANAP00000029155 LOC105721511 LOC105721511 GTF2H2 GTF2H2 ENSANAP00000022525 ENSANAP00000022525 RRN3 RRN3 CDK7 CDK7 UBTF UBTF ERCC6 ERCC6 ENSANAP00000019155 ENSANAP00000019155 POLR2E POLR2E GATAD2A GATAD2A POLR1E POLR1E MAPK3 MAPK3 RBBP7 RBBP7 TAF1C TAF1C CCNH CCNH TTF1 TTF1 ENSANAP00000039038 ENSANAP00000039038 TBP TBP ENSANAP00000038694 ENSANAP00000038694 CHD4 CHD4 GATAD2B GATAD2B ENSANAP00000036175 ENSANAP00000036175 GTF2H3 GTF2H3 HDAC2 HDAC2 LOC105714949 LOC105714949 RBBP4 RBBP4 LOC105715770 LOC105715770 ENSANAP00000015243 ENSANAP00000015243 EHMT2 EHMT2 GTF2H1 GTF2H1 H2AZ1 H2AZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2LRNA polymerase II subunit L. (67 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ZNRD1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
MTA1Metastasis associated 1. (725 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (823 aa)
CBX3Chromobox 3. (183 aa)
CD3EAPCD3e molecule associated protein. (513 aa)
ENSANAP00000008309Chromo domain-containing protein. (97 aa)
POLR2KUncharacterized protein. (67 aa)
MBD2Methyl-CpG binding domain protein 2. (373 aa)
ENSANAP00000024880Uncharacterized protein. (57 aa)
MTA3Metastasis associated 1 family member 3. (586 aa)
DMTF1Cyclin D binding myb like transcription factor 1. (762 aa)
AIREAutoimmune regulator. (540 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2020 aa)
CAVIN1Caveolae associated protein 1. (390 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1719 aa)
LOC105712089WD_REPEATS_REGION domain-containing protein. (250 aa)
ENSANAP00000032176CAF1C_H4-bd domain-containing protein. (80 aa)
ENSANAP00000032143Histone H2A; Belongs to the histone H2A family. (152 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
ENSANAP00000031039Histone H2B; Belongs to the histone H2B family. (129 aa)
ENSANAP00000002458annotation not available (103 aa)
ENSANAP00000002499annotation not available (103 aa)
ENSANAP00000003064annotation not available (136 aa)
LOC105721506Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC8Histone H2B; Belongs to the histone H2B family. (130 aa)
LOC105721512Histone H4. (103 aa)
LOC105716903Histone H3; Belongs to the histone H3 family. (136 aa)
ENSANAP00000003960annotation not available (136 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSANAP00000004003Chromo domain-containing protein. (75 aa)
LOC105721457Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSANAP00000004261annotation not available (136 aa)
ENSANAP00000004291annotation not available (103 aa)
ENSANAP00000004318Histone domain-containing protein. (106 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
TAF1ATATA-box binding protein associated factor, RNA polymerase I subunit A. (450 aa)
POLR2FRNA polymerase II subunit F. (145 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (283 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
MTA2Metastasis associated 1 family member 2. (668 aa)
TAF1DTATA-box binding protein associated factor, RNA polymerase I subunit D. (325 aa)
LOC105722322Histone H3.3. (136 aa)
LOC105719961Histone H3. (136 aa)
ENSANAP00000027055WD_REPEATS_REGION domain-containing protein. (320 aa)
ENSANAP00000026983annotation not available (103 aa)
LOC105709928Histone H4. (103 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (813 aa)
C11orf88Chromosome 11 open reading frame 88. (195 aa)
LOC105726422Histone H2B; Belongs to the histone H2B family. (126 aa)
KAT2ALysine acetyltransferase 2A. (844 aa)
TWISTNBTWIST neighbor. (338 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1163 aa)
MBD3Methyl-CpG binding domain protein 3. (291 aa)
H2BW1H2B histone family member W, testis specific; Belongs to the histone H2B family. (181 aa)
POLR1CRNA polymerase I and III subunit C. (388 aa)
ENSANAP00000001222annotation not available (103 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSANAP00000000978annotation not available (103 aa)
UBN2Ubinuclein 2. (1347 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC105719964Histone H3; Belongs to the histone H3 family. (136 aa)
LOC105713881Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
GCNASprT-like domain-containing protein. (562 aa)
LOC105726425Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSANAP00000000291Histone H3; Belongs to the histone H3 family. (136 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1866 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (170 aa)
LOC105726417Histone H3.1. (136 aa)
LOC110567286Uncharacterized protein. (58 aa)
LOC105726427Histone H4. (103 aa)
LOC105726426Histone H4. (103 aa)
LOC105726406Histone H2B type 1-H. (126 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
LOC105726424Histone H2B type 1-H. (126 aa)
LOC105721499Histone H3.1. (136 aa)
LOC105721488Histone H3.1. (136 aa)
LOC105728434Histone domain-containing protein. (165 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
ENSANAP00000027620annotation not available (103 aa)
TAF1BTATA-box binding protein associated factor, RNA polymerase I subunit B. (587 aa)
LOC105726785Histone H4. (103 aa)
LOC105731119Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSANAP00000029155Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (90 aa)
LOC105721511Uncharacterized protein; Belongs to the histone H2B family. (89 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
ENSANAP00000022525Histone H2A; Belongs to the histone H2A family. (89 aa)
RRN3Uncharacterized protein. (651 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
UBTFUpstream binding transcription factor. (838 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1495 aa)
ENSANAP00000019155WD_REPEATS_REGION domain-containing protein. (365 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
GATAD2AGATA zinc finger domain containing 2A. (654 aa)
POLR1ERNA polymerase I subunit E. (470 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (468 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (844 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
TTF1Uncharacterized protein. (325 aa)
ENSANAP00000039038Uncharacterized protein. (274 aa)
TBPTATA-box binding protein. (325 aa)
ENSANAP00000038694WD_REPEATS_REGION domain-containing protein. (358 aa)
CHD4Uncharacterized protein. (1937 aa)
GATAD2BGATA zinc finger domain containing 2B. (593 aa)
ENSANAP00000036175Uncharacterized protein. (85 aa)
GTF2H3General transcription factor IIH subunit 3. (330 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (465 aa)
LOC105714949Uncharacterized protein. (649 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (425 aa)
LOC105715770WD_REPEATS_REGION domain-containing protein. (426 aa)
ENSANAP00000015243Histone H2A; Belongs to the histone H2A family. (105 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1245 aa)
GTF2H1General transcription factor IIH subunit 1. (556 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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