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H2AC20 | Histone H2A; Belongs to the histone H2A family. (129 aa) | ||||
H2BC15 | Histone H2B; Belongs to the histone H2B family. (170 aa) | ||||
LOC105726425 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
TEN1 | Uncharacterized protein. (123 aa) | ||||
POLR2C | RNA polymerase II subunit C. (275 aa) | ||||
LOC105713881 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
H2AC6 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
ENSANAP00000000978 | annotation not available (103 aa) | ||||
LOC110568754 | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
H2AJ | Histone H2A; Belongs to the histone H2A family. (129 aa) | ||||
ENSANAP00000001222 | annotation not available (103 aa) | ||||
H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
H2AC7 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
LOC105728434 | Histone domain-containing protein. (165 aa) | ||||
CENPI | Centromere protein I. (755 aa) | ||||
ENSANAP00000002458 | annotation not available (103 aa) | ||||
ENSANAP00000002499 | annotation not available (103 aa) | ||||
ENSANAP00000002743 | Uncharacterized protein. (232 aa) | ||||
RFC5 | Replication factor C subunit 5. (340 aa) | ||||
LOC105721506 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
ENSANAP00000003293 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (419 aa) | ||||
SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa) | ||||
RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1325 aa) | ||||
H2BC8 | Histone H2B; Belongs to the histone H2B family. (130 aa) | ||||
LOC105721512 | Histone H4. (103 aa) | ||||
MIS18BP1 | MIS18 binding protein 1. (1073 aa) | ||||
LOC105716903 | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) | ||||
POLR2D | RNA polymerase II subunit D. (142 aa) | ||||
H2BC21 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
CENPC | Centromere protein C. (910 aa) | ||||
LOC105721457 | Histone H2B; Belongs to the histone H2B family. (127 aa) | ||||
ENSANAP00000004291 | annotation not available (103 aa) | ||||
ENSANAP00000004318 | Histone domain-containing protein. (106 aa) | ||||
POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa) | ||||
H2BC5 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa) | ||||
POLR2J | RNA_pol_L_2 domain-containing protein. (153 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
POLR2F | RNA polymerase II subunit F. (145 aa) | ||||
RPA3 | Replication protein A3. (134 aa) | ||||
CENPA | Centromere protein A. (138 aa) | ||||
TINF2 | TERF1 interacting nuclear factor 2. (449 aa) | ||||
ENSANAP00000006932 | Histone H2A; Belongs to the histone H2A family. (131 aa) | ||||
PPP6R3 | Protein phosphatase 6 regulatory subunit 3. (879 aa) | ||||
GAR1 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (248 aa) | ||||
H2AZ2 | Histone H2A; Belongs to the histone H2A family. (128 aa) | ||||
LOC105722322 | Histone H3.3. (136 aa) | ||||
ENSANAP00000008710 | Uncharacterized protein. (273 aa) | ||||
ENSANAP00000008925 | Uncharacterized protein. (111 aa) | ||||
DKC1 | Dyskerin pseudouridine synthase 1. (514 aa) | ||||
TRUB1 | TruB pseudouridine synthase family member 1. (351 aa) | ||||
ANKRD66 | Ankyrin repeat domain 66. (233 aa) | ||||
POLR2L | RNA polymerase II subunit L. (67 aa) | ||||
RCBTB2 | RCC1 and BTB domain containing protein 2. (551 aa) | ||||
CENPX | Centromere protein X. (127 aa) | ||||
NHP2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa) | ||||
SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1039 aa) | ||||
H2AZ1 | Histone H2A; Belongs to the histone H2A family. (128 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa) | ||||
CENPW | Centromere protein W. (102 aa) | ||||
EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) | ||||
RECQL4 | RecQ like helicase 4. (1208 aa) | ||||
RFC2 | Replication factor C subunit 2. (352 aa) | ||||
OIP5 | Opa interacting protein 5. (253 aa) | ||||
POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) | ||||
CENPP | Centromere protein P. (288 aa) | ||||
RSF1 | Remodeling and spacing factor 1. (1436 aa) | ||||
POLD1 | DNA polymerase delta 1, catalytic subunit. (1066 aa) | ||||
ENSANAP00000014871 | Uncharacterized protein. (107 aa) | ||||
ENSANAP00000015243 | Histone H2A; Belongs to the histone H2A family. (105 aa) | ||||
LOC105715770 | WD_REPEATS_REGION domain-containing protein. (426 aa) | ||||
RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) | ||||
LIG1 | DNA ligase. (881 aa) | ||||
H2BW1 | H2B histone family member W, testis specific; Belongs to the histone H2B family. (181 aa) | ||||
PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (678 aa) | ||||
LOC110567669 | Uncharacterized protein. (292 aa) | ||||
RFC1 | Replication factor C subunit 1. (1136 aa) | ||||
WRAP53 | WD repeat containing antisense to TP53. (549 aa) | ||||
TERF2IP | TERF2 interacting protein. (399 aa) | ||||
HJURP | Holliday junction recognition protein. (737 aa) | ||||
CTC1 | CST telomere replication complex component 1. (1214 aa) | ||||
LOC105726422 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
NOP10 | Uncharacterized protein. (64 aa) | ||||
ENSANAP00000019155 | WD_REPEATS_REGION domain-containing protein. (365 aa) | ||||
CDK2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa) | ||||
PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (419 aa) | ||||
POLD2 | DNA polymerase delta 2, accessory subunit. (504 aa) | ||||
POT1 | Protection of telomeres 1. (648 aa) | ||||
ITGB3BP | Integrin subunit beta 3 binding protein. (190 aa) | ||||
PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (507 aa) | ||||
ENSANAP00000022525 | Histone H2A; Belongs to the histone H2A family. (89 aa) | ||||
SHQ1 | CS domain-containing protein. (574 aa) | ||||
KNL1 | Kinetochore scaffold 1. (2118 aa) | ||||
CCNA2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (432 aa) | ||||
DAXX | Death domain associated protein. (740 aa) | ||||
CCNA1 | Cyclin A1; Belongs to the cyclin family. (444 aa) | ||||
POLR2K | Uncharacterized protein. (67 aa) | ||||
ENSANAP00000024880 | Uncharacterized protein. (57 aa) | ||||
POLD3 | DNA polymerase delta 3, accessory subunit. (466 aa) | ||||
ENSANAP00000025287 | Uncharacterized protein. (256 aa) | ||||
MIS18A | MIS18 kinetochore protein A. (232 aa) | ||||
LOC105727589 | SHQ1 domain-containing protein. (500 aa) | ||||
POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) | ||||
CENPH | Centromere protein H. (247 aa) | ||||
LOC105727318 | H/ACA ribonucleoprotein complex subunit 3. (64 aa) | ||||
LOC105709928 | Histone H4. (103 aa) | ||||
ENSANAP00000026983 | annotation not available (103 aa) | ||||
ENSANAP00000027055 | WD_REPEATS_REGION domain-containing protein. (320 aa) | ||||
LOC105726426 | Histone H4. (103 aa) | ||||
LOC105726427 | Histone H4. (103 aa) | ||||
PPP6R2 | Uncharacterized protein. (965 aa) | ||||
LOC110567286 | Uncharacterized protein. (58 aa) | ||||
ENSANAP00000027418 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa) | ||||
LOC105726406 | Histone H2B type 1-H. (126 aa) | ||||
LOC105726424 | Histone H2B type 1-H. (126 aa) | ||||
ENSANAP00000027620 | annotation not available (103 aa) | ||||
LOC105726785 | Histone H4. (103 aa) | ||||
H2AW | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
LOC105731119 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
POLA1 | DNA polymerase. (1475 aa) | ||||
ANKRD28 | Ankyrin repeat domain 28. (1063 aa) | ||||
TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1095 aa) | ||||
CENPM | Centromere protein M. (180 aa) | ||||
ENSANAP00000029155 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (90 aa) | ||||
ATRX | ATRX chromatin remodeler. (2480 aa) | ||||
ENSANAP00000029549 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa) | ||||
RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) | ||||
WRN | WRN RecQ like helicase. (1386 aa) | ||||
LOC105721603 | Uncharacterized protein. (891 aa) | ||||
LOC105721511 | Uncharacterized protein; Belongs to the histone H2B family. (89 aa) | ||||
CENPT | Centromere protein T. (563 aa) | ||||
ACD | ACD shelterin complex subunit and telomerase recruitment factor. (502 aa) | ||||
ENSANAP00000031039 | Histone H2B; Belongs to the histone H2B family. (129 aa) | ||||
LOC105723511 | Uncharacterized protein. (273 aa) | ||||
PPP6C | Serine/threonine-protein phosphatase. (341 aa) | ||||
ENSANAP00000032143 | Histone H2A; Belongs to the histone H2A family. (152 aa) | ||||
ENSANAP00000032176 | CAF1C_H4-bd domain-containing protein. (80 aa) | ||||
MEIOB | Meiosis specific with OB-fold. (447 aa) | ||||
LOC105712089 | WD_REPEATS_REGION domain-containing protein. (250 aa) | ||||
RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) | ||||
POLD4 | Uncharacterized protein. (107 aa) | ||||
RFC4 | Replication factor C subunit 4. (363 aa) | ||||
ENSANAP00000033472 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (248 aa) | ||||
ENSANAP00000034099 | Histone H2B; Belongs to the histone H2B family. (138 aa) | ||||
TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (434 aa) | ||||
NPM1 | Uncharacterized protein. (263 aa) | ||||
CENPU | Centromere protein U. (420 aa) | ||||
CENPO | Centromere protein O. (300 aa) | ||||
POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) | ||||
DSCC1 | DNA replication and sister chromatid cohesion 1. (393 aa) | ||||
CENPQ | Uncharacterized protein. (268 aa) | ||||
ANKRD44 | Ankyrin repeat domain 44. (1056 aa) | ||||
CHTF18 | Chromosome transmission fidelity factor 18. (1159 aa) | ||||
ENSANAP00000036628 | Uncharacterized protein. (218 aa) | ||||
CHTF8 | Chromosome transmission fidelity factor 8. (121 aa) | ||||
RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (477 aa) | ||||
CENPL | Centromere protein L. (390 aa) | ||||
ENSANAP00000038694 | WD_REPEATS_REGION domain-containing protein. (358 aa) | ||||
TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (534 aa) | ||||
POLR2G | RNA polymerase II subunit G. (172 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
DNA2 | DNA replication helicase/nuclease 2. (936 aa) | ||||
RBBP7 | RB binding protein 7, chromatin remodeling factor. (468 aa) | ||||
LOC105725006 | Uncharacterized protein. (292 aa) | ||||
CENPK | Centromere protein K. (269 aa) | ||||
CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (303 aa) | ||||
ENSANAP00000041321 | Uncharacterized protein. (303 aa) | ||||
STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa) | ||||
BLM | BLM RecQ like helicase. (1415 aa) | ||||
POLR2E | RNA polymerase II subunit E. (210 aa) |