STRINGSTRING
POLI POLI PCNA PCNA CUL4B CUL4B RPS27A RPS27A ENSANAP00000041846 ENSANAP00000041846 ATAD5 ATAD5 POLE2 POLE2 RPA1 RPA1 RCBTB2 RCBTB2 SPATA5L1 SPATA5L1 USP31 USP31 DDB1 DDB1 ENSANAP00000007102 ENSANAP00000007102 RPA3 RPA3 TRIM65 TRIM65 RFC3 RFC3 LOC105719658 LOC105719658 LOC105706260 LOC105706260 LOC105716995 LOC105716995 RFC5 RFC5 POLE4 POLE4 WDR48 WDR48 ENSANAP00000000126 ENSANAP00000000126 SPATA5 SPATA5 LOC105720458 LOC105720458 ENSANAP00000014372 ENSANAP00000014372 POLD1 POLD1 USP10 USP10 ENSANAP00000014871 ENSANAP00000014871 ENSANAP00000016653 ENSANAP00000016653 RFC1 RFC1 REV3L REV3L CUL4A CUL4A ENSANAP00000019537 ENSANAP00000019537 POLD2 POLD2 POLE3 POLE3 REV1 REV1 RBX1 RBX1 MAD2L2 MAD2L2 POLD3 POLD3 LOC105732229 LOC105732229 LOC105713378 LOC105713378 TRIM25 TRIM25 UFD1 UFD1 ISG15 ISG15 RCHY1 RCHY1 UBE2L6 UBE2L6 PCLAF PCLAF RAD18 RAD18 TRIM47 TRIM47 VCP VCP POLK POLK MEIOB MEIOB RCBTB1 RCBTB1 POLD4 POLD4 RFC4 RFC4 ENSANAP00000033460 ENSANAP00000033460 USP43 USP43 DTL DTL SPRTN SPRTN USP1 USP1 ENSANAP00000035706 ENSANAP00000035706 ENSANAP00000036022 ENSANAP00000036022 NPLOC4 NPLOC4 RFC2 RFC2 POLH POLH UBA52 UBA52 UBA7 UBA7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLIDNA polymerase iota. (860 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
CUL4BCullin 4B; Belongs to the cullin family. (937 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSANAP00000041846Ubiquitin-like domain-containing protein. (144 aa)
ATAD5ATPase family AAA domain containing 5. (1835 aa)
POLE2DNA polymerase epsilon 2, accessory subunit. (467 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (753 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1334 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
ENSANAP00000007102DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (370 aa)
RPA3Replication protein A3. (134 aa)
TRIM65Tripartite motif containing 65. (515 aa)
RFC3Replication factor C subunit 3. (356 aa)
LOC105719658Ubiquitin-like domain-containing protein. (156 aa)
LOC105706260Ubiquitin-like domain-containing protein. (154 aa)
LOC105716995RING-type domain-containing protein. (108 aa)
RFC5Replication factor C subunit 5. (340 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (119 aa)
WDR48WD repeat domain 48. (677 aa)
ENSANAP00000000126DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (284 aa)
SPATA5Spermatogenesis associated 5. (891 aa)
LOC105720458CULLIN_2 domain-containing protein; Belongs to the cullin family. (307 aa)
ENSANAP00000014372DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (276 aa)
POLD1DNA polymerase delta 1, catalytic subunit. (1066 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa)
ENSANAP00000014871Uncharacterized protein. (107 aa)
ENSANAP00000016653DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (714 aa)
RFC1Replication factor C subunit 1. (1136 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3134 aa)
CUL4ACULLIN_2 domain-containing protein; Belongs to the cullin family. (739 aa)
ENSANAP00000019537Zf-rbx1 domain-containing protein. (116 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (176 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1253 aa)
RBX1Ring-box 1. (108 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (224 aa)
POLD3DNA polymerase delta 3, accessory subunit. (466 aa)
LOC105732229Ubiquitin-like domain-containing protein. (77 aa)
LOC105713378Ubiquitin-like domain-containing protein. (77 aa)
TRIM25Tripartite motif containing 25. (620 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
ISG15ISG15 ubiquitin like modifier. (166 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
PCLAFPAF domain-containing protein. (115 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (495 aa)
TRIM47Tripartite motif containing 47. (605 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (815 aa)
POLKDNA polymerase kappa. (862 aa)
MEIOBMeiosis specific with OB-fold. (447 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
POLD4Uncharacterized protein. (107 aa)
RFC4Replication factor C subunit 4. (363 aa)
ENSANAP00000033460CULLIN_2 domain-containing protein; Belongs to the cullin family. (275 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1123 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
SPRTNSprT-like N-terminal domain. (487 aa)
USP1Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (783 aa)
ENSANAP00000035706Ubiquitin-like domain-containing protein. (101 aa)
ENSANAP00000036022Uncharacterized protein. (113 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (585 aa)
RFC2Replication factor C subunit 2. (352 aa)
POLHDNA polymerase eta. (710 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1012 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.