STRINGSTRING
NOD1 NOD1 ENSANAP00000000124 ENSANAP00000000124 IL1A IL1A IL1B IL1B TAB2 TAB2 ENSANAP00000000667 ENSANAP00000000667 LOC105707274 LOC105707274 ENSANAP00000001198 ENSANAP00000001198 ENSANAP00000001227 ENSANAP00000001227 PSMA7 PSMA7 ENSANAP00000001338 ENSANAP00000001338 TAB3 TAB3 LOC105728767 LOC105728767 LOC105717768 LOC105717768 PSMD2 PSMD2 PSMB9 PSMB9 NLRC5 NLRC5 ENSANAP00000002683 ENSANAP00000002683 PSMF1 PSMF1 LOC105716995 LOC105716995 PSMD1 PSMD1 LOC105706260 LOC105706260 S100B S100B ENSANAP00000003669 ENSANAP00000003669 NLRP9 NLRP9 LOC105726466 LOC105726466 LOC105719658 LOC105719658 PSMD13 PSMD13 PSMA6 PSMA6 SKP1 SKP1 MAP3K8 MAP3K8 PSMD9 PSMD9 MAP2K6 MAP2K6 IRAK4 IRAK4 LOC105720202 LOC105720202 LRRC34 LRRC34 PSMA8 PSMA8 LOC105720203 LOC105720203 APP APP ENSANAP00000006464 ENSANAP00000006464 LRRC45 LRRC45 MAP3K20 MAP3K20 PSMD11 PSMD11 ENSANAP00000007597 ENSANAP00000007597 LOC105706650 LOC105706650 PSMD10 PSMD10 NKIRAS1 NKIRAS1 TONSL TONSL PELI2 PELI2 PSMB8 PSMB8 LOC105721445 LOC105721445 N4BP1 N4BP1 PSME3 PSME3 MAP2K1 MAP2K1 VWC2 VWC2 KHNYN KHNYN MYD88 MYD88 PSMD4 PSMD4 ENSANAP00000012193 ENSANAP00000012193 ENSANAP00000012253 ENSANAP00000012253 LOC105723059 LOC105723059 MAP3K2 MAP3K2 MFSD1 MFSD1 PSMA1 PSMA1 PSME1 PSME1 PSMD12 PSMD12 TOLLIP TOLLIP IL1R1 IL1R1 USP14 USP14 LOC105721341 LOC105721341 PSMC1 PSMC1 IRAK3 IRAK3 MAP3K3 MAP3K3 ENSANAP00000016151 ENSANAP00000016151 LOC105715975 LOC105715975 S100A12 S100A12 ENSANAP00000017252 ENSANAP00000017252 IL1R2 IL1R2 IL1RN IL1RN MAP3K7 MAP3K7 LRRC71 LRRC71 LOC105713290 LOC105713290 ENSANAP00000019537 ENSANAP00000019537 PSMD14 PSMD14 TRAF6 TRAF6 CUL1 CUL1 RBX1 RBX1 CASP8 CASP8 NKIRAS2 NKIRAS2 PELI1 PELI1 PSMB5 PSMB5 ENSANAP00000025026 ENSANAP00000025026 PSMC5 PSMC5 RIPK2 RIPK2 NFKBIA NFKBIA NLRP13 NLRP13 LRRC74A LRRC74A PSMB7 PSMB7 IRAK1 IRAK1 PSMD3 PSMD3 IKBKB IKBKB LOC110568879 LOC110568879 LOC105732229 LOC105732229 LOC105713378 LOC105713378 LOC105731662 LOC105731662 ALPK1 ALPK1 CCDC71L CCDC71L IRAK2 IRAK2 TAB1 TAB1 LRRC31 LRRC31 IKBKG IKBKG NFKBIB NFKBIB PSMC4 PSMC4 LRRC14 LRRC14 PSMB3 PSMB3 PELI3 PELI3 PSMB6 PSMB6 TNIP2 TNIP2 PSMC2 PSMC2 PSMA5 PSMA5 ENSANAP00000031356 ENSANAP00000031356 AGER AGER NFKB1 NFKB1 PSMB10 PSMB10 ENSANAP00000031797 ENSANAP00000031797 PSMC6 PSMC6 ENSANAP00000032311 ENSANAP00000032311 HMGB1 HMGB1 PSMB4 PSMB4 PSMA3 PSMA3 PSMD7 PSMD7 ENSANAP00000033417 ENSANAP00000033417 TRAF2 TRAF2 ENSANAP00000034137 ENSANAP00000034137 PSMB2 PSMB2 ENSANAP00000034576 ENSANAP00000034576 PSME2 PSME2 PSMD8 PSMD8 ENSANAP00000035706 ENSANAP00000035706 ENSANAP00000036022 ENSANAP00000036022 PSMD6 PSMD6 BTRC BTRC PSMB1 PSMB1 IL1RAP IL1RAP RELA RELA ENSANAP00000037220 ENSANAP00000037220 PSME4 PSME4 SQSTM1 SQSTM1 MAP2K4 MAP2K4 NLRX1 NLRX1 LOC105721624 LOC105721624 LOC105709894 LOC105709894 ENSANAP00000038542 ENSANAP00000038542 PSMD5 PSMD5 ENSANAP00000038840 ENSANAP00000038840 FBXW11 FBXW11 UBE2N UBE2N ENSANAP00000039113 ENSANAP00000039113 PSMC3 PSMC3 UBA52 UBA52 ENSANAP00000041359 ENSANAP00000041359 NLRP6 NLRP6 CHUK CHUK NFKB2 NFKB2 RPS27A RPS27A ENSANAP00000041846 ENSANAP00000041846 PSMA2 PSMA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
ENSANAP00000000124AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (231 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSANAP00000000667Proteasome endopeptidase complex. (261 aa)
LOC105707274AAA domain-containing protein. (352 aa)
ENSANAP00000001198Uncharacterized protein; Belongs to the SKP1 family. (158 aa)
ENSANAP00000001227Uncharacterized protein. (99 aa)
PSMA7Proteasome subunit alpha type. (252 aa)
ENSANAP00000001338Uncharacterized protein. (192 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
LOC105728767Proteasome subunit alpha type. (263 aa)
LOC105717768Proteasome subunit alpha type. (234 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB9Proteasome subunit beta. (219 aa)
NLRC5NLR family CARD domain containing 5. (1815 aa)
ENSANAP00000002683Uncharacterized protein. (204 aa)
PSMF1Proteasome inhibitor subunit 1. (267 aa)
LOC105716995RING-type domain-containing protein. (108 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
LOC105706260Ubiquitin-like domain-containing protein. (154 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
ENSANAP00000003669Uncharacterized protein. (190 aa)
NLRP9NLR family pyrin domain containing 9. (934 aa)
LOC105726466Proteasome endopeptidase complex. (242 aa)
LOC105719658Ubiquitin-like domain-containing protein. (156 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (378 aa)
PSMA6Proteasome subunit alpha type. (253 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (451 aa)
PSMD9Uncharacterized protein. (250 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
LOC105720202Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (142 aa)
LRRC34Leucine rich repeat containing 34. (464 aa)
PSMA8Proteasome subunit alpha type. (256 aa)
LOC105720203Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa)
APPAmyloid beta precursor protein. (741 aa)
ENSANAP00000006464UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
LRRC45Leucine rich repeat containing 45. (674 aa)
MAP3K20Protein kinase domain-containing protein. (461 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ENSANAP00000007597ANK_REP_REGION domain-containing protein. (190 aa)
LOC105706650Uncharacterized protein. (190 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
TONSLTonsoku like, DNA repair protein. (1371 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
PSMB8Proteasome subunit beta 8. (250 aa)
LOC105721445Uncharacterized protein. (244 aa)
N4BP1NEDD4 binding protein 1. (810 aa)
PSME3Proteasome activator subunit 3. (267 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
KHNYNKH and NYN domain containing. (642 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (353 aa)
ENSANAP00000012193UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
ENSANAP00000012253Proteasome endopeptidase complex. (205 aa)
LOC105723059Uncharacterized protein. (220 aa)
MAP3K2Uncharacterized protein. (619 aa)
MFSD1Major facilitator superfamily domain containing 1. (475 aa)
PSMA1Proteasome subunit alpha type. (283 aa)
PSME1Proteasome activator subunit 1. (250 aa)
PSMD12PCI domain-containing protein. (456 aa)
TOLLIPToll interacting protein. (274 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa)
LOC105721341Uncharacterized protein. (397 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (589 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (705 aa)
ENSANAP00000016151Uncharacterized protein. (202 aa)
LOC105715975Uncharacterized protein. (596 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (80 aa)
ENSANAP00000017252Uncharacterized protein. (107 aa)
IL1R2Interleukin 1 receptor type 2. (404 aa)
IL1RNInterleukin-1. (179 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LRRC71Leucine rich repeat containing 71. (552 aa)
LOC105713290AAA domain-containing protein; Belongs to the AAA ATPase family. (352 aa)
ENSANAP00000019537Zf-rbx1 domain-containing protein. (116 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (312 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
RBX1Ring-box 1. (108 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (525 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (239 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSANAP00000025026Uncharacterized protein. (218 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
NFKBIANFKB inhibitor alpha. (310 aa)
NLRP13NLR family pyrin domain containing 13. (985 aa)
LRRC74ALeucine rich repeat containing 74A. (487 aa)
PSMB7Proteasome subunit beta. (277 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (711 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
LOC110568879UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
LOC105732229Ubiquitin-like domain-containing protein. (77 aa)
LOC105713378Ubiquitin-like domain-containing protein. (77 aa)
LOC105731662Ubiquitin conjugating enzyme E2 V1. (147 aa)
ALPK1Alpha kinase 1. (1262 aa)
CCDC71LUncharacterized protein. (253 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (605 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (505 aa)
LRRC31Leucine rich repeat containing 31. (590 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
PSMB3Proteasome subunit beta. (205 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
PSMB6Proteasome subunit beta. (281 aa)
TNIP2TNFAIP3 interacting protein 2. (424 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSANAP00000031356Uncharacterized protein; Belongs to the SKP1 family. (154 aa)
AGERAdvanced glycosylation end-product specific receptor. (419 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
PSMB10Proteasome subunit beta. (273 aa)
ENSANAP00000031797Uncharacterized protein. (416 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
ENSANAP00000032311AAA domain-containing protein; Belongs to the AAA ATPase family. (412 aa)
HMGB1High mobility group box 1. (215 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (244 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMD7MPN domain-containing protein. (324 aa)
ENSANAP00000033417Uncharacterized protein. (338 aa)
TRAF2TNF receptor-associated factor. (493 aa)
ENSANAP00000034137Uncharacterized protein. (369 aa)
PSMB2Proteasome subunit beta. (201 aa)
ENSANAP00000034576Uncharacterized protein. (186 aa)
PSME2Uncharacterized protein. (254 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
ENSANAP00000035706Ubiquitin-like domain-containing protein. (101 aa)
ENSANAP00000036022Uncharacterized protein. (113 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (435 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (606 aa)
PSMB1Proteasome subunit beta. (241 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
RELARELA proto-oncogene, NF-kB subunit. (540 aa)
ENSANAP00000037220Uncharacterized protein. (221 aa)
PSME4Proteasome activator subunit 4. (1840 aa)
SQSTM1Sequestosome 1. (440 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (375 aa)
NLRX1NLR family member X1. (975 aa)
LOC105721624ANK_REP_REGION domain-containing protein. (232 aa)
LOC105709894Proteasome endopeptidase complex. (222 aa)
ENSANAP00000038542Proteasome subunit alpha type. (190 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (507 aa)
ENSANAP00000038840Uncharacterized protein. (221 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSANAP00000039113UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (113 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (454 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSANAP00000041359Uncharacterized protein. (193 aa)
NLRP6NLR family pyrin domain containing 6. (883 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSANAP00000041846Ubiquitin-like domain-containing protein. (144 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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