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LOC105714684 | Uncharacterized protein. (591 aa) | ||||
SOCS1 | Suppressor of cytokine signaling 1. (211 aa) | ||||
EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (194 aa) | ||||
IFNAR1 | Interferon alpha and beta receptor subunit 1. (511 aa) | ||||
IL2RA | Interleukin 2 receptor subunit alpha. (272 aa) | ||||
IL5RA | Interleukin 5 receptor subunit alpha. (420 aa) | ||||
EPOR | Erythropoietin receptor; Receptor for erythropoietin. (509 aa) | ||||
LOC105729323 | Uncharacterized protein. (216 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) | ||||
IL27RA | Interleukin 27 receptor subunit alpha. (549 aa) | ||||
ENSANAP00000022162 | Uncharacterized protein. (163 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) | ||||
LOC105711369 | Uncharacterized protein. (221 aa) | ||||
SOCS7 | Suppressor of cytokine signaling 7. (579 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (781 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) | ||||
IFNE | Interferon epsilon. (179 aa) | ||||
IL22RA1 | Interleukin 22 receptor subunit alpha 1. (573 aa) | ||||
STAM | Signal transducing adaptor molecule. (536 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa) | ||||
IL6R | Interleukin 6 receptor. (378 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) | ||||
IL22 | Interleukin 22. (179 aa) | ||||
STAT6 | Signal transducer and activator of transcription. (847 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1132 aa) | ||||
OSM | Oncostatin M. (249 aa) | ||||
PTPN2 | Tyrosine-protein phosphatase non-receptor type. (415 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
GHR | Growth hormone receptor. (638 aa) | ||||
IL9 | Interleukin 9. (144 aa) | ||||
ENSANAP00000015746 | SH2 domain-containing protein. (503 aa) | ||||
EP300 | E1A binding protein p300. (2401 aa) | ||||
IL11 | Interleukin 11. (199 aa) | ||||
TSLP | Thymic stromal lymphopoietin. (158 aa) | ||||
PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (402 aa) | ||||
AOX1 | Aldehyde oxidase 1. (1338 aa) | ||||
IL20RB | Interleukin 20 receptor subunit beta. (311 aa) | ||||
ENSANAP00000013875 | Uncharacterized protein. (317 aa) | ||||
STAT4 | Signal transducer and activator of transcription. (748 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (463 aa) | ||||
IFNL3 | Uncharacterized protein. (199 aa) | ||||
IFNLR1 | Interferon lambda receptor 1. (519 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) | ||||
LOC105731455 | FAD-binding PCMH-type domain-containing protein. (1332 aa) | ||||
PIAS1 | Protein inhibitor of activated STAT 1. (654 aa) | ||||
CNTFR | Ciliary neurotrophic factor receptor. (372 aa) | ||||
CREBBP | CREB binding protein. (2445 aa) | ||||
PIAS4 | Protein inhibitor of activated STAT 4. (546 aa) | ||||
CSF3 | Colony stimulating factor 3. (207 aa) | ||||
IFNGR1 | Interferon gamma receptor 1. (483 aa) | ||||
IL19 | Interleukin 19. (214 aa) | ||||
IL10RB | Interleukin 10 receptor subunit beta. (325 aa) | ||||
IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
ENSANAP00000008016 | Uncharacterized protein. (215 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (152 aa) | ||||
IL20 | Interleukin 20. (176 aa) | ||||
MCL1 | MCL1 apoptosis regulator, BCL2 family member. (352 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
IFNAR2 | Uncharacterized protein. (603 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
IL6ST | Interleukin 6 signal transducer. (922 aa) | ||||
ENSANAP00000006063 | SH2 domain-containing protein. (230 aa) | ||||
IL6 | Interleukin 6. (213 aa) | ||||
IL12RB1 | Interleukin 12 receptor subunit beta 1. (649 aa) | ||||
IL23A | Interleukin 23 subunit alpha. (189 aa) | ||||
IL10 | Interleukin 10. (178 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
IL24 | Interleukin 24. (205 aa) | ||||
LOC105729267 | Uncharacterized protein. (238 aa) | ||||
CSF2 | Colony stimulating factor 2. (144 aa) | ||||
IL2RB | Interleukin 2 receptor subunit beta. (551 aa) | ||||
PIAS3 | Uncharacterized protein. (628 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) | ||||
IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa) | ||||
THPO | Thrombopoietin. (307 aa) | ||||
CSF2RA | Uncharacterized protein. (412 aa) | ||||
IL2RG | Fibronectin type-III domain-containing protein. (345 aa) | ||||
SOCS6 | Suppressor of cytokine signaling 6. (534 aa) | ||||
JAK3 | Tyrosine-protein kinase. (1119 aa) | ||||
SOCS3 | Suppressor of cytokine signaling 3. (225 aa) | ||||
LIFR | LIF receptor subunit alpha. (1141 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) | ||||
SOCS4 | Suppressor of cytokine signaling 4. (440 aa) | ||||
LEPR | Leptin receptor. (1165 aa) | ||||
IL4R | Interleukin 4 receptor. (830 aa) | ||||
IFNK | Interferon kappa. (167 aa) | ||||
IL13RA1 | Interleukin 13 receptor subunit alpha 1. (425 aa) | ||||
PIK3R2 | Uncharacterized protein. (640 aa) | ||||
STAM2 | Signal transducing adaptor molecule 2. (525 aa) | ||||
CNTF | Ciliary neurotrophic factor. (200 aa) | ||||
GALT | Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (772 aa) | ||||
IL23R | Interleukin 23 receptor. (575 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1110 aa) | ||||
IL13 | Interleukin 13. (146 aa) | ||||
OSMR | Oncostatin M receptor. (977 aa) | ||||
MPL | MPL proto-oncogene, thrombopoietin receptor. (689 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1153 aa) | ||||
TYK2 | Tyrosine-protein kinase. (1226 aa) | ||||
IL3 | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (143 aa) | ||||
IRF9 | Interferon regulatory factor 9. (394 aa) | ||||
ENSANAP00000039717 | SOCS box domain-containing protein. (462 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (158 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (768 aa) | ||||
PIK3R3 | Uncharacterized protein. (478 aa) | ||||
IL5 | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa) | ||||
PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (621 aa) | ||||
LOC105711370 | Uncharacterized protein. (159 aa) | ||||
IFNGR2 | Interferon gamma receptor 2. (328 aa) | ||||
IL13RA2 | Interleukin 13 receptor subunit alpha 2. (386 aa) | ||||
IFNL1 | Uncharacterized protein. (201 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1055 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (600 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
CTF1 | Cardiotrophin 1. (201 aa) | ||||
CSF3R | Colony stimulating factor 3 receptor. (834 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (503 aa) | ||||
CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) | ||||
FHL1 | Four and a half LIM domains 1. (323 aa) | ||||
STAT2 | Signal transducer and activator of transcription. (849 aa) | ||||
IL21R | Interleukin 21 receptor. (538 aa) | ||||
CISH | Cytokine inducible SH2 containing protein. (274 aa) | ||||
IL20RA | Interleukin 20 receptor subunit alpha. (552 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (240 aa) | ||||
BCL2L1 | BCL2 like 1. (233 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (723 aa) | ||||
IL12RB2 | Interleukin 12 receptor subunit beta 2. (860 aa) | ||||
IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
LIF | LIF interleukin 6 family cytokine. (202 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (897 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (230 aa) | ||||
IL22RA2 | Interleukin 22 receptor subunit alpha 2. (251 aa) | ||||
IL15RA | Interleukin 15 receptor subunit alpha. (240 aa) | ||||
ENSANAP00000035262 | Uncharacterized protein. (134 aa) | ||||
IL10RA | Interleukin 10 receptor subunit alpha. (579 aa) | ||||
IL7R | Interleukin 7 receptor. (459 aa) | ||||
PRL | Prolactin. (228 aa) | ||||
SOCS2 | Suppressor of cytokine signaling 2. (198 aa) | ||||
EGFR | Epidermal growth factor receptor. (705 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (805 aa) | ||||
PIAS2 | Protein inhibitor of activated STAT 2. (621 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
SOCS5 | Uncharacterized protein. (536 aa) |