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ANAPC5 ANAPC5 S100A9 S100A9 IL1B IL1B TAB2 TAB2 IFNG IFNG TAB3 TAB3 FOSL1 FOSL1 ENSANAP00000003370 ENSANAP00000003370 ENSANAP00000003515 ENSANAP00000003515 MAPK10 MAPK10 CSF2 CSF2 MAPK8 MAPK8 S100A8 S100A8 SRSF1 SRSF1 IL17B IL17B MMP13 MMP13 IL6 IL6 LOC105709072 LOC105709072 IL17RC IL17RC ENSANAP00000006458 ENSANAP00000006458 LOC105714282 LOC105714282 IL4 IL4 MAPK13 MAPK13 CXCL10 CXCL10 TRAF3 TRAF3 IL17RE IL17RE CCL17 CCL17 CCL7 CCL7 CSF3 CSF3 ENSANAP00000010892 ENSANAP00000010892 PTGS2 PTGS2 HSP90B1 HSP90B1 IL25 IL25 MAPK9 MAPK9 MAPK7 MAPK7 LOC105725360 LOC105725360 LOC105726866 LOC105726866 CASP3 CASP3 CCL11 CCL11 MAPK1 MAPK1 ENSANAP00000015054 ENSANAP00000015054 TRAF3IP2 TRAF3IP2 CEBPB CEBPB GSK3B GSK3B CCL20 CCL20 TRAF5 TRAF5 MAP3K7 MAP3K7 USP25 USP25 CXCL1 CXCL1 ENSANAP00000019200 ENSANAP00000019200 IKBKE IKBKE MAPK15 MAPK15 TRAF6 TRAF6 MAPK6 MAPK6 TBK1 TBK1 CASP8 CASP8 MMP1 MMP1 ENSANAP00000022681 ENSANAP00000022681 TNFAIP3 TNFAIP3 FOS FOS MMP3 MMP3 ENSANAP00000025464 ENSANAP00000025464 NFKBIA NFKBIA LOC105707629 LOC105707629 FADD FADD MAPK4 MAPK4 IKBKB IKBKB IL17C IL17C LOC105727636 LOC105727636 IKBKG IKBKG MMP9 MMP9 IL17RA IL17RA NFKB1 NFKB1 CXCL5 CXCL5 LOC105714240 LOC105714240 CXCL8 CXCL8 MAPK12 MAPK12 TRAF2 TRAF2 CXCL6 CXCL6 LOC105705743 LOC105705743 IL17RB IL17RB MAPK11 MAPK11 FOSB FOSB RELA RELA IL17F IL17F IL17A IL17A TRAF4 TRAF4 IL13 IL13 HSP90AB1 HSP90AB1 HSP90AA1 HSP90AA1 ELAVL1 ELAVL1 IL5 IL5 MAPK3 MAPK3 CCL2 CCL2 TRADD TRADD MAPK14 MAPK14 CHUK CHUK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
S100A9Protein S100; Belongs to the S-100 family. (131 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
ENSANAP00000003370Uncharacterized protein. (119 aa)
ENSANAP00000003515HATPase_c domain-containing protein. (532 aa)
MAPK10Mitogen-activated protein kinase. (533 aa)
CSF2Colony stimulating factor 2. (144 aa)
MAPK8Mitogen-activated protein kinase. (387 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
SRSF1Uncharacterized protein. (253 aa)
IL17BInterleukin 17B. (163 aa)
MMP13Matrix metallopeptidase 13. (488 aa)
IL6Interleukin 6. (213 aa)
LOC105709072HATPase_c domain-containing protein. (329 aa)
IL17RCSEFIR domain-containing protein. (780 aa)
ENSANAP00000006458Uncharacterized protein. (307 aa)
LOC105714282HATPase_c domain-containing protein. (736 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (152 aa)
MAPK13Mitogen-activated protein kinase. (392 aa)
CXCL10C-X-C motif chemokine. (97 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (571 aa)
IL17REInterleukin 17 receptor E. (570 aa)
CCL17C-C motif chemokine. (102 aa)
CCL7C-C motif chemokine. (98 aa)
CSF3Colony stimulating factor 3. (207 aa)
ENSANAP00000010892S_100 domain-containing protein; Belongs to the S-100 family. (78 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
HSP90B1HATPase_c domain-containing protein. (818 aa)
IL25Interleukin 25. (177 aa)
MAPK9Mitogen-activated protein kinase 9. (442 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
LOC105725360C-X-C motif chemokine. (107 aa)
LOC105726866IL17_R_N domain-containing protein. (235 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
CCL11C-C motif chemokine. (107 aa)
MAPK1Mitogen-activated protein kinase. (376 aa)
ENSANAP00000015054RRM domain-containing protein. (203 aa)
TRAF3IP2TRAF3 interacting protein 2. (560 aa)
CEBPBCCAAT/enhancer-binding protein. (321 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
CCL20C-C motif chemokine. (96 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (527 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
USP25Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1125 aa)
CXCL1C-X-C motif chemokine. (107 aa)
ENSANAP00000019200Protein kinase domain-containing protein. (670 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
MAPK15Protein kinase domain-containing protein. (246 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
MAPK6Protein kinase domain-containing protein. (721 aa)
TBK1TANK binding kinase 1. (690 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (525 aa)
MMP1Matrix metallopeptidase 1. (469 aa)
ENSANAP00000022681SEFIR domain-containing protein. (735 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
ENSANAP00000025464CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (249 aa)
NFKBIANFKB inhibitor alpha. (310 aa)
LOC105707629Uncharacterized protein. (729 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (207 aa)
MAPK4Mitogen-activated protein kinase 4. (587 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IL17CInterleukin 17C. (197 aa)
LOC105727636ELAV-like protein; Belongs to the RRM elav family. (315 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
IL17RASEFIR domain-containing protein. (728 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
CXCL5C-X-C motif chemokine. (107 aa)
LOC105714240HATPase_c domain-containing protein. (712 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
TRAF2TNF receptor-associated factor. (493 aa)
CXCL6C-X-C motif chemokine. (114 aa)
LOC105705743HATPase_c domain-containing protein. (629 aa)
IL17RBInterleukin 17 receptor B. (501 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (337 aa)
RELARELA proto-oncogene, NF-kB subunit. (540 aa)
IL17FInterleukin 17F. (163 aa)
IL17AInterleukin 17A. (153 aa)
TRAF4TNF receptor-associated factor. (470 aa)
IL13Interleukin 13. (146 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (703 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (790 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (328 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
CCL2C-C motif chemokine. (99 aa)
TRADDTNFRSF1A associated via death domain. (312 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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