STRINGSTRING
PLA2G4B PLA2G4B WASF3 WASF3 RAF1 RAF1 SPHK1 SPHK1 AKT3 AKT3 PIK3CD PIK3CD ENSANAP00000026903 ENSANAP00000026903 ENSANAP00000026737 ENSANAP00000026737 PLA2G4D PLA2G4D LOC105707475 LOC105707475 CRK CRK ENSANAP00000024583 ENSANAP00000024583 LOC105715307 LOC105715307 RPS6KB2 RPS6KB2 SCIN SCIN ASAP1 ASAP1 WASF2 WASF2 CFL1 CFL1 ASAP3 ASAP3 VAV3 VAV3 INPPL1 INPPL1 PRKCB PRKCB AKT1 AKT1 PIK3CA PIK3CA PLD1 PLD1 CRKL CRKL RPS6KB1 RPS6KB1 LOC105709925 LOC105709925 ENSANAP00000016068 ENSANAP00000016068 JMJD7 JMJD7 PIP5K1B PIP5K1B PLPP3 PLPP3 MAPK1 MAPK1 ENSANAP00000014481 ENSANAP00000014481 PLCG2 PLCG2 GSN GSN VAV2 VAV2 PRKCE PRKCE PLPP2 PLPP2 BIN1 BIN1 ENSANAP00000012488 ENSANAP00000012488 ASAP2 ASAP2 ARPC1B ARPC1B MARCKS MARCKS PRKCG PRKCG ARPC3 ARPC3 MAP2K1 MAP2K1 AMPH AMPH SYK SYK ARPC2 ARPC2 LAT LAT PLD2 PLD2 LOC105705722 LOC105705722 PRKCD PRKCD PIK3CB PIK3CB ARPC5L ARPC5L AKT2 AKT2 LYN LYN LOC105709929 LOC105709929 GOLGA2 GOLGA2 PLA2G4F PLA2G4F ARPC5 ARPC5 PIK3R2 PIK3R2 CFL2 CFL2 ENSANAP00000000391 ENSANAP00000000391 PLCG1 PLCG1 WAS WAS LOC105719430 LOC105719430 ENSANAP00000001107 ENSANAP00000001107 ENSANAP00000001524 ENSANAP00000001524 ENSANAP00000001555 ENSANAP00000001555 WASF1 WASF1 CCDC125 CCDC125 ARF6 ARF6 LIMK2 LIMK2 ENSANAP00000002846 ENSANAP00000002846 LOC105731627 LOC105731627 ENSANAP00000003167 ENSANAP00000003167 LOC105732437 LOC105732437 PAK1 PAK1 ENSANAP00000003753 ENSANAP00000003753 LOC105707993 LOC105707993 PTPRC PTPRC VAV1 VAV1 ARPC1A ARPC1A PLA2G6 PLA2G6 PLA2G4E PLA2G4E MAPK3 MAPK3 PIK3R3 PIK3R3 DNM2 DNM2 ARPC4 ARPC4 HCK HCK ENSANAP00000039407 ENSANAP00000039407 INPP5D INPP5D PIP5K1C PIP5K1C MYO10 MYO10 LIMK1 LIMK1 LOC105710938 LOC105710938 LOC105713523 LOC105713523 NCF1 NCF1 LOC105729816 LOC105729816 PLA2G4A PLA2G4A CDC42 CDC42 VASP VASP FCGR2A FCGR2A MARCKSL1 MARCKSL1 PRKCA PRKCA DOCK1 DOCK1 PIK3R1 PIK3R1 GAB2 GAB2 SPHK2 SPHK2 ENSANAP00000030418 ENSANAP00000030418 PLPP1 PLPP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4BPhospholipase A2. (781 aa)
WASF3WASP family member 3. (502 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
SPHK1Sphingosine kinase 1. (469 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1055 aa)
ENSANAP00000026903Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ENSANAP00000026737ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (142 aa)
PLA2G4DPhospholipase A2. (812 aa)
LOC105707475Uncharacterized protein. (348 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ENSANAP00000024583Uncharacterized protein. (176 aa)
LOC105715307Uncharacterized protein. (254 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (483 aa)
SCINScinderin. (715 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1129 aa)
WASF2WASP family member 2. (498 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (190 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (886 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1254 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLD1Phospholipase. (1091 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC105709925Uncharacterized protein. (422 aa)
ENSANAP00000016068Uncharacterized protein. (289 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (625 aa)
PLPP3acidPPc domain-containing protein. (311 aa)
MAPK1Mitogen-activated protein kinase. (376 aa)
ENSANAP00000014481Ig-like domain-containing protein. (184 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
GSNGelsolin. (764 aa)
VAV2Vav guanine nucleotide exchange factor 2. (866 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PLPP2Phospholipid phosphatase 2. (296 aa)
BIN1Bridging integrator 1. (611 aa)
ENSANAP00000012488Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (161 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1006 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (377 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (339 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (162 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
AMPHAmphiphysin. (695 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (302 aa)
LATLinker for activation of T cells. (268 aa)
PLD2Phospholipase. (933 aa)
LOC105705722Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (367 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (161 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LYNLYN proto-oncogene, Src family tyrosine kinase. (498 aa)
LOC105709929ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (161 aa)
GOLGA2Golgin A2. (1026 aa)
PLA2G4FPhospholipase A2. (849 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
PIK3R2Uncharacterized protein. (640 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
ENSANAP00000000391Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
WASWASP actin nucleation promoting factor. (544 aa)
LOC105719430ADF-H domain-containing protein. (212 aa)
ENSANAP00000001107Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (279 aa)
ENSANAP00000001524Uncharacterized protein. (166 aa)
ENSANAP00000001555Uncharacterized protein. (66 aa)
WASF1WASP family member 1. (559 aa)
CCDC125Coiled-coil domain containing 125. (511 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
LIMK2LIM domain kinase 2. (638 aa)
ENSANAP00000002846ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (144 aa)
LOC105731627WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (373 aa)
ENSANAP00000003167Uncharacterized protein. (190 aa)
LOC105732437Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
ENSANAP00000003753Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (160 aa)
LOC105707993Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (451 aa)
PTPRCUncharacterized protein. (1299 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
PLA2G4EPhospholipase A2. (863 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
PIK3R3Uncharacterized protein. (478 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (868 aa)
ARPC4Uncharacterized protein. (219 aa)
HCKTyrosine-protein kinase. (505 aa)
ENSANAP00000039407PIPK domain-containing protein. (574 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1108 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (828 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa)
LIMK1LIM domain kinase 1. (593 aa)
LOC105710938Uncharacterized protein. (179 aa)
LOC105713523ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (214 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
LOC105729816Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (166 aa)
PLA2G4APhospholipase A2. (750 aa)
CDC42Uncharacterized protein. (191 aa)
VASPWH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
FCGR2AUncharacterized protein. (317 aa)
MARCKSL1MARCKS like 1. (197 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1865 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)
GAB2GRB2 associated binding protein 2. (666 aa)
SPHK2Sphingosine kinase 2. (657 aa)
ENSANAP00000030418Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (160 aa)
PLPP1Phospholipid phosphatase 1. (285 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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