STRINGSTRING
MAPK14 MAPK14 LAMB1 LAMB1 CHUK CHUK HLA-DPB1 HLA-DPB1 LY96 LY96 TAB2 TAB2 ENSANAP00000000642 ENSANAP00000000642 IFNG IFNG HSPA1L HSPA1L GNAO1 GNAO1 GNAI3 GNAI3 LOC105730458 LOC105730458 LOC105708942 LOC105708942 MAPK10 MAPK10 MAPK8 MAPK8 PDPK1 PDPK1 MAP2K6 MAP2K6 IRAK4 IRAK4 IL10 IL10 ENSANAP00000005921 ENSANAP00000005921 ITGA6 ITGA6 LAMA3 LAMA3 AKT2 AKT2 NOS2 NOS2 IL10RB IL10RB MAPK13 MAPK13 IFNGR1 IFNGR1 ENSANAP00000009193 ENSANAP00000009193 LAMA4 LAMA4 ITGB1 ITGB1 LOC105704663 LOC105704663 MYD88 MYD88 HLA-DOA HLA-DOA CD40LG CD40LG HLA-DQA2 HLA-DQA2 ENSANAP00000012107 ENSANAP00000012107 ENSANAP00000012173 ENSANAP00000012173 LOC105705668 LOC105705668 MAPK9 MAPK9 HLA-DMA HLA-DMA CASP3 CASP3 HLA-DQB2 HLA-DQB2 HSPA2 HSPA2 MAPK1 MAPK1 LOC105704667 LOC105704667 HLA-DPA1 HLA-DPA1 XIAP XIAP GNAI1 GNAI1 PPP1R14B PPP1R14B LAMB3 LAMB3 TLR4 TLR4 JAK2 JAK2 HLA-DRA HLA-DRA MAP3K7 MAP3K7 C7orf31 C7orf31 LOC105732281 LOC105732281 AKT1 AKT1 CD40 CD40 TRAF6 TRAF6 LAMA1 LAMA1 STAT1 STAT1 PPIF PPIF CIITA CIITA LOC110568101 LOC110568101 IL12A IL12A CASP8 CASP8 MAP2K3 MAP2K3 LOC105724646 LOC105724646 TGFB3 TGFB3 IRGM IRGM ALOX5 ALOX5 LAMA5 LAMA5 ENSANAP00000025464 ENSANAP00000025464 NFKBIA NFKBIA IRAK1 IRAK1 IKBKB IKBKB LOC105704661 LOC105704661 SOCS1 SOCS1 LOC105732154 LOC105732154 AKT3 AKT3 PIK3R6 PIK3R6 TAB1 TAB1 LAMA2 LAMA2 BAD BAD LAMC2 LAMC2 IKBKG IKBKG NFKBIB NFKBIB TGFB2 TGFB2 TNFRSF1A TNFRSF1A BCL2 BCL2 BCL2L1 BCL2L1 NFKB1 NFKB1 LAMB4 LAMB4 ENSANAP00000031715 ENSANAP00000031715 GNAI2 GNAI2 LOC105708941 LOC105708941 MAPK12 MAPK12 HSPA8 HSPA8 CASP9 CASP9 PIK3CG PIK3CG IL10RA IL10RA MAPK11 MAPK11 LAMC1 LAMC1 LAMC3 LAMC3 RELA RELA TGFB1 TGFB1 BIRC3 BIRC3 STAT3 STAT3 LDLR LDLR JAK1 JAK1 ENSANAP00000038686 ENSANAP00000038686 BIRC7 BIRC7 TYK2 TYK2 BIRC2 BIRC2 MAPK3 MAPK3 PIK3R5 PIK3R5 IFNGR2 IFNGR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK14Mitogen-activated protein kinase. (360 aa)
LAMB1Laminin subunit beta 1. (1839 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
LY96Lymphocyte antigen 96. (160 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSANAP00000000642Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
GNAO1G protein subunit alpha o1. (354 aa)
GNAI3Uncharacterized protein. (354 aa)
LOC105730458Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
LOC105708942Ig-like domain-containing protein. (318 aa)
MAPK10Mitogen-activated protein kinase. (533 aa)
MAPK8Mitogen-activated protein kinase. (387 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (572 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
IL10Interleukin 10. (178 aa)
ENSANAP00000005921Uncharacterized protein. (73 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1225 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
MAPK13Mitogen-activated protein kinase. (392 aa)
IFNGR1Interferon gamma receptor 1. (483 aa)
ENSANAP00000009193Uncharacterized protein. (290 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LOC105704663Ig-like domain-containing protein. (271 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
HLA-DQA2Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa)
ENSANAP00000012107Uncharacterized protein. (193 aa)
ENSANAP00000012173Uncharacterized protein; Belongs to the heat shock protein 70 family. (608 aa)
LOC105705668Uncharacterized protein. (441 aa)
MAPK9Mitogen-activated protein kinase 9. (442 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
HLA-DQB2Major histocompatibility complex, class II, DQ beta 2. (274 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (601 aa)
MAPK1Mitogen-activated protein kinase. (376 aa)
LOC105704667Ig-like domain-containing protein; Belongs to the MHC class II family. (262 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
GNAI1G protein subunit alpha i1. (354 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (146 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
C7orf31Chromosome 7 open reading frame 31. (589 aa)
LOC105732281Uncharacterized protein; Belongs to the heat shock protein 70 family. (636 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
CD40CD40 molecule. (274 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
LAMA1Laminin subunit alpha 1. (3020 aa)
STAT1Signal transducer and activator of transcription. (781 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
CIITAClass II major histocompatibility complex transactivator. (1287 aa)
LOC110568101Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (525 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (392 aa)
LOC105724646Uncharacterized protein. (151 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
IRGMImmunity related GTPase M. (188 aa)
ALOX5Arachidonate 5-lipoxygenase. (699 aa)
LAMA5Laminin subunit alpha 5. (3587 aa)
ENSANAP00000025464CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (249 aa)
NFKBIANFKB inhibitor alpha. (310 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (711 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
LOC105704661Ig-like domain-containing protein. (263 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
LOC105732154Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (505 aa)
LAMA2Laminin subunit alpha 2. (3140 aa)
BADBCL2 associated agonist of cell death. (167 aa)
LAMC2Laminin subunit gamma 2. (1140 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (486 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
BCL2L1BCL2 like 1. (233 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
LAMB4Laminin subunit beta 4. (1749 aa)
ENSANAP00000031715Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
GNAI2G protein subunit alpha i2. (359 aa)
LOC105708941Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (396 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
IL10RAInterleukin 10 receptor subunit alpha. (579 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
LAMC1Laminin subunit gamma 1. (1559 aa)
LAMC3Laminin subunit gamma 3. (1450 aa)
RELARELA proto-oncogene, NF-kB subunit. (540 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (378 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
STAT3Signal transducer and activator of transcription. (805 aa)
LDLRLow density lipoprotein receptor. (786 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
ENSANAP00000038686Uncharacterized protein; Belongs to the heat shock protein 70 family. (621 aa)
BIRC7Baculoviral IAP repeat containing 7. (290 aa)
TYK2Tyrosine-protein kinase. (1226 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (878 aa)
IFNGR2Interferon gamma receptor 2. (328 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
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